Zentalis Pharmaceuticals (ZNTL) EBIT (2019 - 2026)

Zentalis Pharmaceuticals' (ZNTL) quarterly EBIT came in at -$37.9 million in Q1 2026, up 17.03% year-on-year from -$32.3 million in Q1 2025, and down 1.24% quarter-over-quarter from -$37.4 million in Q4 2025.

Zentalis Pharmaceuticals (ZNTL) EBIT (2019 - 2026) Analysis & Trends

Zentalis Pharmaceuticals' EBIT history runs 8 years deep, the most recent figure standing at -$37.9 million for Q1 2026.

  • On a quarterly basis, EBIT rose 17.03% year-over-year to -$37.9 million in Q1 2026; TTM through Mar 2026 was -$145.0 million, a 31.6% increase from a year earlier, with the FY2025 full-year figure at -$152.8 million, up 20.08% from the prior year.
  • EBIT eased to -$37.9 million in Q1 2026 per ZNTL's latest filing, from -$37.4 million in the prior quarter.
  • Across five years, EBIT topped out at -$24.8 million in Q1 2024 and bottomed at -$103.9 million in Q2 2023.
  • The 5-year median for EBIT is -$51.8 million (2022), against an average of -$53.5 million.
  • Across the five-year window, EBIT soared 61.87% in 2024 and plunged 84.22% in 2025, its largest moves.
  • Year by year, EBIT stood at -$51.8 million in 2022, then slumped by 31.24% to -$67.9 million in 2023, then rose by 26.61% to -$49.8 million in 2024, then rose by 24.99% to -$37.4 million in 2025, then decreased by 1.24% to -$37.9 million in 2026.
  • Per Business Quant, the three latest ZNTL EBIT figures stand at -$37.9 million (Q1 2026), -$37.4 million (Q4 2025), and -$33.7 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Zentalis Pharmaceuticals 302.14 Mn 302.14 Mn - -37.86 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -37.86 Mn
Dec 31, 2025 -37.39 Mn
Sep 30, 2025 -33.73 Mn
Jun 30, 2025 -36.06 Mn
Mar 31, 2025 -45.62 Mn
Dec 31, 2024 -49.85 Mn
Sep 30, 2024 -51.43 Mn
Jun 30, 2024 -65.15 Mn
Mar 31, 2024 -24.77 Mn
Dec 31, 2023 -67.92 Mn
Sep 30, 2023 -62.72 Mn
Jun 30, 2023 -103.92 Mn
Mar 31, 2023 -64.95 Mn
Dec 31, 2022 -51.75 Mn
Sep 30, 2022 -54.19 Mn
Jun 30, 2022 -63.46 Mn
Mar 31, 2022 -57.88 Mn
Dec 31, 2021 -48.19 Mn
Sep 30, 2021 -62.87 Mn
Jun 30, 2021 -55.13 Mn