Zenas BioPharma (ZBIO) Return on Sales (2023 - 2026)

Zenas BioPharma (ZBIO) posted quarterly Return on Sales of 0.39% for Q4 2025, down 28.0% year-over-year from 0.54% in Q4 2024, and down 207.51% quarter-over-quarter from 0.13% in Q3 2025.

Zenas BioPharma (ZBIO) Return on Sales (2023 - 2026) Analysis & Trends

Zenas BioPharma's Return on Sales history runs 3 years deep, the most recent figure standing at 0.39% for Q4 2025.

  • In Q4 2025, Return on Sales fell 28.0% year-over-year to 0.39%; the TTM figure through Dec 2025 stood at 0.39% (down 8.0% YoY), while the FY2025 annual figure was 0.39%, down 7.0% from the prior year.
  • Return on Sales for Q4 2025 stood at 0.39%, down from 0.13% in the prior quarter.
  • The five-year high for Return on Sales was 0.01% in Q3 2023, with the low at 0.39% in Q4 2025.
  • The 3-year median for Return on Sales is 0.1% (2024), against an average of 0.11%.
  • The sharpest annual moves came in 2024 and 2025: Return on Sales declined 3 bps in 2024, then declined 28 bps in 2025.
  • Zenas BioPharma's Return on Sales stood at 0.01% in 2023, then slumped by 1565 bps to 0.1% in 2024, then tumbled by 272 bps to 0.39% in 2025.
  • Business Quant data shows ZBIO's Return on Sales at 0.39% in Q4 2025, 0.13% in Q3 2025, and 0.12% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Zenas BioPharma 1.87 Bn 748.44 Mn - -1.11%

Historic Data

Download Data
DateValue
Jun 30, 2026 -1.11%
Dec 31, 2025 -0.39%
Sep 30, 2025 -0.13%
Jun 30, 2025 -0.12%
Mar 31, 2025 -0.03%
Dec 31, 2024 -0.10%
Sep 30, 2024 -0.03%
Sep 30, 2023 0.01%