Zenas BioPharma (ZBIO) Return on Sales (2023 - 2025)

Zenas BioPharma's Return on Sales history runs 3 years deep, the most recent figure standing at 0.39% for Q4 2025.

• In Q4 2025, Return on Sales fell 28.0% year-over-year to 0.39%; the TTM figure through Dec 2025 stood at 0.39% (down 7.0% YoY), while the FY2025 annual figure was 0.39%, down 7.0% from the prior year.
• Return on Sales was 0.39% for Q4 2025 at Zenas BioPharma, down from 0.13% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 0.01% in Q3 2023 to a low of 0.39% in Q4 2025.
• Historically, Return on Sales has averaged 0.11% across 3 years, with a median of 0.11% in 2024.
• The sharpest annual moves came in 2024 and 2025: Return on Sales fell 3 bps in 2024, then fell 28 bps in 2025.
• A 3-year view of Return on Sales shows it stood at 0.01% in 2023, then tumbled by 1687 bps to 0.11% in 2024, then tumbled by 244 bps to 0.39% in 2025.
• The last three Return on Sales figures came in at 0.39% (Q4 2025), 0.13% (Q3 2025), and 0.12% (Q2 2025), per Business Quant data.