Zenas BioPharma (ZBIO) Return on Sales (2023 - 2025)
Zenas BioPharma's (ZBIO) quarterly Return on Sales came in at 0.39% in Q4 2025, down 28.0% year-on-year from 0.54% in Q4 2024, and down 207.51% quarter-over-quarter from 0.13% in Q3 2025.
Zenas BioPharma (ZBIO) Return on Sales (2023 - 2025) Analysis & Trends
Zenas BioPharma's Return on Sales history runs 3 years deep, the most recent figure standing at 0.39% for Q4 2025.
- On a quarterly basis, Return on Sales fell 28.0% year-over-year to 0.39% in Q4 2025; TTM through Dec 2025 was 0.39%, a 8.0% decrease from a year earlier, with the FY2025 full-year figure at 0.39%, down 7.0% from the prior year.
- Return on Sales retreated to 0.39% in Q4 2025 per ZBIO's latest filing, from 0.13% in the prior quarter.
- Across five years, Return on Sales topped out at 0.01% in Q3 2023 and bottomed at 0.39% in Q4 2025.
- The 3-year median for Return on Sales is 0.1% (2024), against an average of 0.11%.
- Across the five-year window, Return on Sales decreased 3 bps in 2024 and decreased 28 bps in 2025, its largest moves.
- Year by year, Return on Sales stood at 0.01% in 2023, then sank by 1565 bps to 0.1% in 2024, then slumped by 272 bps to 0.39% in 2025.
- Per Business Quant, the three latest ZBIO Return on Sales figures stand at 0.39% (Q4 2025), 0.13% (Q3 2025), and 0.12% (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 0.00% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 0.00% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 0.00% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 0.00% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Zenas BioPharma | 1.72 Bn | 1.72 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -0.39% |
| Sep 30, 2025 | -0.13% |
| Jun 30, 2025 | -0.12% |
| Mar 31, 2025 | -0.03% |
| Dec 31, 2024 | -0.10% |
| Sep 30, 2024 | -0.03% |
| Sep 30, 2023 | 0.01% |