Zenas BioPharma (ZBIO) Return on Sales (2023 - 2025)

Zenas BioPharma's (ZBIO) quarterly Return on Sales came in at 0.39% in Q4 2025, down 28.0% year-on-year from 0.54% in Q4 2024, and down 207.51% quarter-over-quarter from 0.13% in Q3 2025.

Zenas BioPharma (ZBIO) Return on Sales (2023 - 2025) Analysis & Trends

Zenas BioPharma's Return on Sales history runs 3 years deep, the most recent figure standing at 0.39% for Q4 2025.

  • On a quarterly basis, Return on Sales fell 28.0% year-over-year to 0.39% in Q4 2025; TTM through Dec 2025 was 0.39%, a 8.0% decrease from a year earlier, with the FY2025 full-year figure at 0.39%, down 7.0% from the prior year.
  • Return on Sales retreated to 0.39% in Q4 2025 per ZBIO's latest filing, from 0.13% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.01% in Q3 2023 and bottomed at 0.39% in Q4 2025.
  • The 3-year median for Return on Sales is 0.1% (2024), against an average of 0.11%.
  • Across the five-year window, Return on Sales decreased 3 bps in 2024 and decreased 28 bps in 2025, its largest moves.
  • Year by year, Return on Sales stood at 0.01% in 2023, then sank by 1565 bps to 0.1% in 2024, then slumped by 272 bps to 0.39% in 2025.
  • Per Business Quant, the three latest ZBIO Return on Sales figures stand at 0.39% (Q4 2025), 0.13% (Q3 2025), and 0.12% (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Zenas BioPharma 1.72 Bn 1.72 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -0.39%
Sep 30, 2025 -0.13%
Jun 30, 2025 -0.12%
Mar 31, 2025 -0.03%
Dec 31, 2024 -0.10%
Sep 30, 2024 -0.03%
Sep 30, 2023 0.01%