Zenas BioPharma, Inc. (ZBIO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

15,333,097Shares held by institutions

$279,752,355Value of institutional holdings

80.50%Institutional ownership %

3.92%Shares Changed QoQ

70No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Zenas BioPharma, Inc. (NASDAQ:ZBIO) showed up in the 13F filings of 114 institutional investors as of December 2025.

These investors collectively held 97.7% of Zenas BioPharma's outstanding shares in December 2025, up from 82.7% in September 2025.
Their total shares held in ZBIO increased 26.2% quarter over quarter, and separately, investors owning Zenas BioPharma increased 75.38% from a year ago.
Among the 114 funds, 81 bought more Zenas BioPharma shares, 23 sold down, and 10 held their ground.
Institutional investors collectively held 41.19Mn shares in Zenas BioPharma as of December 2025, up by 8.55Mn shares quarter on quarter, and up 10.89Mn shares year over year.
FMR LLC leads ownership in ZBIO with 7.7Mn shares as of December 31, 2025, equal to 18.27% of outstanding shares.
Leading buyers of Zenas BioPharma shares for the quarter ending December 2025 were FMR LLC (2.88Mn), Polar Capital Holdings Plc (1.06Mn), Federated Hermes, Inc. (853.74K), NEA Management Company, LLC (789.5K), EcoR1 Capital, LLC (789.5K).
Top sellers of ZBIO stock for the quarter ending December 2025 included Novo Holdings A/S (550.0K), Vivo Capital, LLC (329.76K), Pivotal bioVenture Partners Investment Advisor LLC (187.05K), Rock Springs Capital Management LP (78.6K), ArrowMark Colorado Holdings LLC (73.51K).
Per Business Quant, the top 10 investors in ZBIO for the quarter ending December 2025 include FMR LLC (7.7Mn), SR ONE CAPITAL MANAGEMENT, LP (5.04Mn), Enavate Sciences GP, LLC (3.92Mn), NEA Management Company, LLC (3.52Mn), Federated Hermes, Inc. (2.72Mn), Fairmount Funds Management LLC (2.21Mn), NVP Associates, LLC (1.84Mn), BlackRock, Inc. (1.77Mn), VANGUARD GROUP INC (1.45Mn), Novo Holdings A/S (1.45Mn).

114 Institutional Holders

15,333,097 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	538,877	43.86%	$0.00
FMR LLC	31 Dec, 2025	2,883,885	59.83%	$0.00
SR ONE CAPITAL MANAGEMENT, LP	31 Dec, 2025	126,315	2.57%	$0.00
Barclays Plc	31 Dec, 2025	-3,999	-10.42%	$0.00
NEA Management Company, LLC	31 Dec, 2025	789,500	28.88%	$0.00
Enavate Sciences GP, LLC	31 Dec, 2025	157,800	4.20%	$0.00
Federated Hermes, Inc.	31 Dec, 2025	853,740	45.85%	$0.00
Fairmount Funds Management LLC	31 Dec, 2025	316,219	16.71%	$0.00
NVP Associates, LLC	31 Dec, 2025	0	0.00%	$0.00
Polar Capital Holdings Plc	31 Dec, 2025	1,057,609	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	290,307	24.97%	$0.00
Vivo Capital, LLC	31 Dec, 2025	-329,765	-27.87%	$0.00
Novo Holdings A/S	31 Dec, 2025	-550,000	-27.50%	$0.00
Pivotal bioVenture Partners Investment Advisor LLC	31 Dec, 2025	-187,054	-24.01%	$0.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	-2,190	-0.26%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	368,400	0.00%	$0.00
EcoR1 Capital, LLC	31 Dec, 2025	789,500	0.00%	$0.00
NEXTBio Capital Management LP	31 Dec, 2025	321,983	0.00%	$0.00
ArrowMark Colorado Holdings LLC	31 Dec, 2025	-73,507	-8.91%	$0.00
Eversept Partners, LP	31 Dec, 2025	-37,726	-23.77%	$0.00

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