Xilio Therapeutics (XLO) Return on Sales [ROS] (2024 - 2026)
Xilio Therapeutics (XLO) recorded Return on Sales [ROS] of -18.68% in Q2 2026, up 159.03 percentage points from -177.71% a year earlier and up 92.90 percentage points from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) Return on Sales [ROS] (2024 - 2026) Analysis & Trends
On a TTM basis, Xilio Therapeutics' Return on Sales [ROS] came in at -48.94% as of Jun 30, 2026, up 328.42 percentage points year-over-year; for FY2025, it came in at -95.92%, up 859.03 percentage points from FY2024.
- Across earlier years, Return on Sales [ROS] came in at -954.95% in FY2024.
- Quarterly Return on Sales [ROS] has ranged from -790.55% in Q4 2024 to -10.12% in Q3 2025 over the past five years.
- On a year-over-year basis, Return on Sales [ROS] has increased for five consecutive quarters, with an average year-over-year change of +462.52 percentage points over the last five quarters.
- Per Business Quant, the preceding three quarters came in at -111.57% (Q1 2026), -86.48% (Q4 2025) and -10.12% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,142.35 Bn | 1,110.94 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 635.52 Bn | 555.38 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 501.09 Bn | 474.20 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 356.35 Bn | 310.72 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 300.53 Bn | 264.52 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 263.02 Bn | 236.71 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 238.00 Bn | 193.40 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 194.35 Bn | 168.55 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 170.37 Bn | 117.02 Bn | 10.94 Bn | 28.37% |
| 10 | Xilio Therapeutics | 156.60 Mn | -371.07 Mn | - | -18.68% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -18.68% |
| Mar 31, 2026 | -111.57% |
| Dec 31, 2025 | -86.48% |
| Sep 30, 2025 | -10.12% |
| Jun 30, 2025 | -177.71% |
| Mar 31, 2025 | -472.73% |
| Dec 31, 2024 | -790.55% |
| Sep 30, 2024 | -652.32% |
| Jun 30, 2024 | -623.84% |
API Access
Xilio Therapeutics Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();