Xilio Therapeutics (XLO) Return on Equity [ROE] (2021 - 2026)
Xilio Therapeutics' Return on Equity [ROE] was -43.32% in Q2 2026, up 593.83 percentage points from -637.15% a year earlier and up 35.04 percentage points from the prior quarter.
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Analysis
Xilio Therapeutics (XLO) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Xilio Therapeutics came in at -158.81%, up 63.82 percentage points from FY2024.
- Return on Equity [ROE] shows a four-year change of -11.87 percentage points (FY2021 to FY2025).
- In earlier years, Return on Equity [ROE] was -222.63% in FY2024 (-111.54 pp), -111.08% in FY2023 (-49.83 pp), -61.25% in FY2022 (+85.69 pp) and -146.94% in FY2021.
- The Q2 2026 figure marks the highest quarterly Return on Equity [ROE] in data going back to Q4 2021.
- Compared with a year earlier, Return on Equity [ROE] has increased for three straight quarters, with an average year-over-year change of +15.71 percentage points over the last seven quarters.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q2 2026 (a gain of 593.83 percentage points); the worst was Q2 2025 (a drop of 408.43 percentage points).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,124.59 Bn | 1,093.18 Bn | 19.71 Bn | 82.09% |
| 2 | Johnson & Johnson | 634.91 Bn | 554.77 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 505.42 Bn | 478.53 Bn | 12.70 Bn | - |
| 4 | Merck | 357.53 Bn | 311.91 Bn | 12.21 Bn | 7.21% |
| 5 | Novartis Ag | 289.90 Bn | 253.89 Bn | 11.24 Bn | 31.52% |
| 6 | Astrazeneca | 264.89 Bn | 238.58 Bn | 12.86 Bn | 21.39% |
| 7 | Amgen | 237.79 Bn | 193.19 Bn | 7.24 Bn | 83.75% |
| 8 | Gilead Sciences | 194.74 Bn | 168.94 Bn | 6.22 Bn | -18.38% |
| 9 | Pfizer | 171.08 Bn | 117.73 Bn | 10.94 Bn | 4.97% |
| 10 | Xilio Therapeutics | 153.30 Mn | -374.37 Mn | - | -43.32% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -43.32% |
| Mar 31, 2026 | -78.36% |
| Dec 31, 2025 | -308.94% |
| Jun 30, 2025 | -637.15% |
| Mar 31, 2025 | -402.47% |
| Dec 31, 2024 | -314.12% |
| Sep 30, 2024 | -239.32% |
| Jun 30, 2024 | -228.73% |
| Mar 31, 2024 | -233.56% |
| Dec 31, 2023 | -177.18% |
| Sep 30, 2023 | -140.43% |
| Jun 30, 2023 | -114.37% |
| Mar 31, 2023 | -96.04% |
| Dec 31, 2022 | -76.87% |
| Sep 30, 2022 | -63.24% |
| Jun 30, 2022 | -52.39% |
| Mar 31, 2022 | -45.37% |
| Dec 31, 2021 | -306.46% |
API Access
Xilio Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XLO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XLO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XLO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();