Xilio Therapeutics (XLO) Profit After Tax (2020 - 2026)

Xilio Therapeutics' (XLO) quarterly Profit After Tax came in at -$14.1 million in Q1 2026, down 6.39% year-on-year from -$15.1 million in Q1 2025, and down 19.23% quarter-over-quarter from -$11.8 million in Q4 2025.

Xilio Therapeutics (XLO) Profit After Tax (2020 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed Profit After Tax across 7 years of filings, most recently posting -$14.1 million for Q1 2026.

  • Profit After Tax for Q1 2026 came in at -$14.1 million, down 6.39% year-over-year; the trailing twelve-month figure through Mar 2026 was -$42.2 million (up 22.28% YoY), and the FY2025 annual result was -$42.0 million, up 27.92% from the prior year.
  • Profit After Tax came in at -$14.1 million for Q1 2026 at Xilio Therapeutics, down from -$11.8 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$1.9 million in Q3 2025 to a low of -$24.6 million in Q2 2022.
  • The 5-year median for Profit After Tax is -$16.7 million (2023), against an average of -$16.4 million.
  • Across the five-year window, Profit After Tax declined 28.12% in 2022 and jumped 86.24% in 2025, its largest moves.
  • Xilio Therapeutics' Profit After Tax stood at -$22.4 million in 2022, then rose by 20.98% to -$17.7 million in 2023, then gained by 25.76% to -$13.1 million in 2024, then gained by 9.93% to -$11.8 million in 2025, then slipped by 19.23% to -$14.1 million in 2026.
  • The last three Profit After Tax figures came in at -$14.1 million (Q1 2026), -$11.8 million (Q4 2025), and -$1.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 30.90 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.63 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -753,254.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.96 Bn 91.96 Bn - -56.74 Mn
10 Xilio Therapeutics 144.35 Mn -5.95 Mn - -14.11 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -14.11 Mn
Dec 31, 2025 -11.84 Mn
Sep 30, 2025 -1.93 Mn
Jun 30, 2025 -14.37 Mn
Mar 31, 2025 -13.27 Mn
Dec 31, 2024 -13.14 Mn
Sep 30, 2024 -14.02 Mn
Jun 30, 2024 -13.93 Mn
Mar 31, 2024 -17.20 Mn
Dec 31, 2023 -17.70 Mn
Sep 30, 2023 -16.75 Mn
Jun 30, 2023 -19.36 Mn
Mar 31, 2023 -22.60 Mn
Dec 31, 2022 -22.40 Mn
Sep 30, 2022 -19.79 Mn
Jun 30, 2022 -24.61 Mn
Mar 31, 2022 -21.35 Mn
Dec 31, 2021 -19.70 Mn
Sep 30, 2021 -16.25 Mn
Jun 30, 2021 -23.18 Mn