X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025)
X4 Pharmaceuticals posted quarterly Research & Development of $18.5 million for Q4 2025, down 14.66% year-on-year from $21.7 million in Q4 2024, and up 6.83% on a QoQ basis from $17.3 million in Q3 2025.
X4 Pharmaceuticals (XFOR) has 9 years of Research & Development data on file, last reported at $18.5 million in Q4 2025.
- For the quarter ending Q4 2025, Research & Development fell 14.66% year-over-year to $18.5 million; the trailing twelve-month figure through Dec 2025 stood at $72.7 million (down 10.93% YoY), and the FY2025 full-year result was $72.7 million, down 10.93% from the prior year.
- Research & Development for Q4 2025 stood at $18.5 million, up from $17.3 million in the prior quarter.
- Across five years, Research & Development topped out at $22.1 million in Q1 2023 and bottomed at $12.1 million in Q1 2021.
- The 5-year median for Research & Development is $17.8 million (2025), against an average of $16.9 million.
- The widest annual swing landed in 2022, when Research & Development soared 56.34%; it then declined 19.68% in 2023.
- A 5-year view of Research & Development shows it stood at $12.2 million in 2021, then soared by 56.34% to $19.0 million in 2022, then slipped by 19.68% to $15.3 million in 2023, then surged by 42.1% to $21.7 million in 2024, then retreated by 14.66% to $18.5 million in 2025.
- The last three Research & Development figures came in at $18.5 million (Q4 2025), $17.3 million (Q3 2025), and $18.4 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | 626,092.00 |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | 4.32 Mn |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | -101.30 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | 1.46 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 961.60 Mn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | -2.30 Mn |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 1.54 Bn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 364.87 Mn |
| 10 | X4 Pharmaceuticals | 182.28 Mn | 182.28 Mn | 2.20 Mn | 18.52 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 18.52 Mn |
| Sep 30, 2025 | 17.34 Mn |
| Jun 30, 2025 | 18.35 Mn |
| Mar 31, 2025 | 18.51 Mn |
| Dec 31, 2024 | 21.70 Mn |
| Sep 30, 2024 | 19.17 Mn |
| Jun 30, 2024 | 20.91 Mn |
| Mar 31, 2024 | 19.85 Mn |
| Dec 31, 2023 | 15.27 Mn |
| Sep 30, 2023 | 19.08 Mn |
| Jun 30, 2023 | 15.60 Mn |
| Mar 31, 2023 | 22.06 Mn |
| Dec 31, 2022 | 19.01 Mn |
| Sep 30, 2022 | 14.11 Mn |
| Jun 30, 2022 | 13.82 Mn |
| Mar 31, 2022 | 14.11 Mn |
| Dec 31, 2021 | 12.16 Mn |
| Sep 30, 2021 | 13.19 Mn |
| Jun 30, 2021 | 13.19 Mn |
| Mar 31, 2021 | 12.10 Mn |
| Dec 31, 2020 | 12.30 Mn |
| Sep 30, 2020 | 11.38 Mn |
| Jun 30, 2020 | 9.34 Mn |
| Mar 31, 2020 | 8.91 Mn |
| Dec 31, 2019 | 7.07 Mn |
| Sep 30, 2019 | 8.59 Mn |
| Jun 30, 2019 | 8.85 Mn |
| Mar 31, 2019 | 5.66 Mn |
| Dec 31, 2018 | 4.69 Mn |
| Sep 30, 2018 | 6.16 Mn |
| Jun 30, 2018 | 4.76 Mn |
| Mar 31, 2018 | 4.74 Mn |
| Dec 31, 2017 | -1.83 Mn |
| Sep 30, 2017 | 10.60 Mn |
| Jun 30, 2017 | 3.91 Mn |
| Mar 31, 2017 | 4.39 Mn |