X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025)
X4 Pharmaceuticals (XFOR) posted Research & Development of $18.5 million for Q4 2025, up 6.83% on a QoQ basis from $17.3 million in Q3 2025, and down 14.66% year-over-year from $21.7 million in Q4 2024.
X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025) Analysis & Trends
X4 Pharmaceuticals' Research & Development history runs 9 years deep, the most recent figure standing at $18.5 million for Q4 2025.
- Quarterly Research & Development fell 14.66% year-over-year to $18.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $72.7 million (down 10.93% YoY) and the FY2025 annual result came in at $72.7 million, down 10.93% from the prior year.
- Research & Development was $18.5 million for Q4 2025 at X4 Pharmaceuticals, up from $17.3 million in the prior quarter.
- Across five years, Research & Development topped out at $22.1 million in Q1 2023 and bottomed at $12.1 million in Q1 2021.
- A 5-year average of $16.9 million and a median of $17.8 million in 2025 frame the typical range for Research & Development.
- Annual changes were most pronounced in 2022 — Research & Development soared 56.34% — and 2023, when it decreased 19.68%.
- X4 Pharmaceuticals' Research & Development stood at $12.2 million in 2021, then jumped by 56.34% to $19.0 million in 2022, then dropped by 19.68% to $15.3 million in 2023, then soared by 42.1% to $21.7 million in 2024, then decreased by 14.66% to $18.5 million in 2025.
- Business Quant data shows XFOR's Research & Development at $18.5 million in Q4 2025, $17.3 million in Q3 2025, and $18.4 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,741.39 Bn | 66,741.11 Bn | - | -17.94 Mn |
| 2 | Nanobiotix | 1,913.26 Bn | 1,913.20 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 1.46 Mn |
| 4 | BeOne Medicines | 471.02 Bn | 466.23 Bn | 1.35 Bn | 541.22 Mn |
| 5 | Vertex Pharmaceuticals | 122.17 Bn | 114.92 Bn | 2.59 Bn | 961.60 Mn |
| 6 | Regeneron Pharmaceuticals | 69.85 Bn | 61.10 Bn | 3.31 Bn | 1.54 Bn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | 15.66 Mn |
| 8 | Argenx Se | 55.60 Bn | 50.42 Bn | 1.41 Bn | 1.37 Bn |
| 9 | Alnylam Pharmaceuticals | 37.39 Bn | 34.38 Bn | 959.66 Mn | 364.87 Mn |
| 10 | X4 Pharmaceuticals | 167.27 Mn | -49.78 Mn | 2.20 Mn | 18.52 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 18.52 Mn |
| Sep 30, 2025 | 17.34 Mn |
| Jun 30, 2025 | 18.35 Mn |
| Mar 31, 2025 | 18.51 Mn |
| Dec 31, 2024 | 21.70 Mn |
| Sep 30, 2024 | 19.17 Mn |
| Jun 30, 2024 | 20.91 Mn |
| Mar 31, 2024 | 19.85 Mn |
| Dec 31, 2023 | 15.27 Mn |
| Sep 30, 2023 | 19.08 Mn |
| Jun 30, 2023 | 15.60 Mn |
| Mar 31, 2023 | 22.06 Mn |
| Dec 31, 2022 | 19.01 Mn |
| Sep 30, 2022 | 14.11 Mn |
| Jun 30, 2022 | 13.82 Mn |
| Mar 31, 2022 | 14.11 Mn |
| Dec 31, 2021 | 12.16 Mn |
| Sep 30, 2021 | 13.19 Mn |
| Jun 30, 2021 | 13.19 Mn |
| Mar 31, 2021 | 12.10 Mn |