X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025)

X4 Pharmaceuticals posted quarterly Research & Development of $18.5 million for Q4 2025, down 14.66% year-on-year from $21.7 million in Q4 2024, and up 6.83% on a QoQ basis from $17.3 million in Q3 2025.

X4 Pharmaceuticals (XFOR) has 9 years of Research & Development data on file, last reported at $18.5 million in Q4 2025.

  • For the quarter ending Q4 2025, Research & Development fell 14.66% year-over-year to $18.5 million; the trailing twelve-month figure through Dec 2025 stood at $72.7 million (down 10.93% YoY), and the FY2025 full-year result was $72.7 million, down 10.93% from the prior year.
  • Research & Development for Q4 2025 stood at $18.5 million, up from $17.3 million in the prior quarter.
  • Across five years, Research & Development topped out at $22.1 million in Q1 2023 and bottomed at $12.1 million in Q1 2021.
  • The 5-year median for Research & Development is $17.8 million (2025), against an average of $16.9 million.
  • The widest annual swing landed in 2022, when Research & Development soared 56.34%; it then declined 19.68% in 2023.
  • A 5-year view of Research & Development shows it stood at $12.2 million in 2021, then soared by 56.34% to $19.0 million in 2022, then slipped by 19.68% to $15.3 million in 2023, then surged by 42.1% to $21.7 million in 2024, then retreated by 14.66% to $18.5 million in 2025.
  • The last three Research & Development figures came in at $18.5 million (Q4 2025), $17.3 million (Q3 2025), and $18.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 626,092.00
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - 4.32 Mn
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -101.30 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - 1.46 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 961.60 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -2.30 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 1.54 Bn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 364.87 Mn
10 X4 Pharmaceuticals 182.28 Mn 182.28 Mn 2.20 Mn 18.52 Mn

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 18.52 Mn
Sep 30, 2025 17.34 Mn
Jun 30, 2025 18.35 Mn
Mar 31, 2025 18.51 Mn
Dec 31, 2024 21.70 Mn
Sep 30, 2024 19.17 Mn
Jun 30, 2024 20.91 Mn
Mar 31, 2024 19.85 Mn
Dec 31, 2023 15.27 Mn
Sep 30, 2023 19.08 Mn
Jun 30, 2023 15.60 Mn
Mar 31, 2023 22.06 Mn
Dec 31, 2022 19.01 Mn
Sep 30, 2022 14.11 Mn
Jun 30, 2022 13.82 Mn
Mar 31, 2022 14.11 Mn
Dec 31, 2021 12.16 Mn
Sep 30, 2021 13.19 Mn
Jun 30, 2021 13.19 Mn
Mar 31, 2021 12.10 Mn
Dec 31, 2020 12.30 Mn
Sep 30, 2020 11.38 Mn
Jun 30, 2020 9.34 Mn
Mar 31, 2020 8.91 Mn
Dec 31, 2019 7.07 Mn
Sep 30, 2019 8.59 Mn
Jun 30, 2019 8.85 Mn
Mar 31, 2019 5.66 Mn
Dec 31, 2018 4.69 Mn
Sep 30, 2018 6.16 Mn
Jun 30, 2018 4.76 Mn
Mar 31, 2018 4.74 Mn
Dec 31, 2017 -1.83 Mn
Sep 30, 2017 10.60 Mn
Jun 30, 2017 3.91 Mn
Mar 31, 2017 4.39 Mn