X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025)

X4 Pharmaceuticals (XFOR) posted Research & Development of $18.5 million for Q4 2025, up 6.83% on a QoQ basis from $17.3 million in Q3 2025, and down 14.66% year-over-year from $21.7 million in Q4 2024.

X4 Pharmaceuticals (XFOR) Research & Development (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals' Research & Development history runs 9 years deep, the most recent figure standing at $18.5 million for Q4 2025.

  • Quarterly Research & Development fell 14.66% year-over-year to $18.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $72.7 million (down 10.93% YoY) and the FY2025 annual result came in at $72.7 million, down 10.93% from the prior year.
  • Research & Development was $18.5 million for Q4 2025 at X4 Pharmaceuticals, up from $17.3 million in the prior quarter.
  • Across five years, Research & Development topped out at $22.1 million in Q1 2023 and bottomed at $12.1 million in Q1 2021.
  • A 5-year average of $16.9 million and a median of $17.8 million in 2025 frame the typical range for Research & Development.
  • Annual changes were most pronounced in 2022 — Research & Development soared 56.34% — and 2023, when it decreased 19.68%.
  • X4 Pharmaceuticals' Research & Development stood at $12.2 million in 2021, then jumped by 56.34% to $19.0 million in 2022, then dropped by 19.68% to $15.3 million in 2023, then soared by 42.1% to $21.7 million in 2024, then decreased by 14.66% to $18.5 million in 2025.
  • Business Quant data shows XFOR's Research & Development at $18.5 million in Q4 2025, $17.3 million in Q3 2025, and $18.4 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 66,741.39 Bn 66,741.11 Bn - -17.94 Mn
2 Nanobiotix 1,913.26 Bn 1,913.20 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 1.46 Mn
4 BeOne Medicines 471.02 Bn 466.23 Bn 1.35 Bn 541.22 Mn
5 Vertex Pharmaceuticals 122.17 Bn 114.92 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 69.85 Bn 61.10 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 62.72 Bn 62.72 Bn - 15.66 Mn
8 Argenx Se 55.60 Bn 50.42 Bn 1.41 Bn 1.37 Bn
9 Alnylam Pharmaceuticals 37.39 Bn 34.38 Bn 959.66 Mn 364.87 Mn
10 X4 Pharmaceuticals 167.27 Mn -49.78 Mn 2.20 Mn 18.52 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 18.52 Mn
Sep 30, 2025 17.34 Mn
Jun 30, 2025 18.35 Mn
Mar 31, 2025 18.51 Mn
Dec 31, 2024 21.70 Mn
Sep 30, 2024 19.17 Mn
Jun 30, 2024 20.91 Mn
Mar 31, 2024 19.85 Mn
Dec 31, 2023 15.27 Mn
Sep 30, 2023 19.08 Mn
Jun 30, 2023 15.60 Mn
Mar 31, 2023 22.06 Mn
Dec 31, 2022 19.01 Mn
Sep 30, 2022 14.11 Mn
Jun 30, 2022 13.82 Mn
Mar 31, 2022 14.11 Mn
Dec 31, 2021 12.16 Mn
Sep 30, 2021 13.19 Mn
Jun 30, 2021 13.19 Mn
Mar 31, 2021 12.10 Mn