X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025)

X4 Pharmaceuticals (XFOR) posted Net Cash Flow of $147.4 million for Q4 2025, up 384.37% on a QoQ basis from $30.4 million in Q3 2025, and up 455.4% year-over-year from $26.5 million in Q4 2024.

X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals' Net Cash Flow history runs 9 years deep, the most recent figure standing at $147.4 million for Q4 2025.

  • Quarterly Net Cash Flow rose 455.4% year-over-year to $147.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $161.2 million (up 308.65% YoY) and the FY2025 annual result came in at $161.2 million, up 469.5% from the prior year.
  • Net Cash Flow was $147.4 million for Q4 2025 at X4 Pharmaceuticals, up from $30.4 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $147.4 million in Q4 2025 and bottomed at -$52.8 million in Q3 2023.
  • A 5-year average of $1.5 million and a median of -$15.4 million in 2022 frame the typical range for Net Cash Flow.
  • Annual changes were most pronounced in 2022 — Net Cash Flow soared 654.31% — and 2023, when it tumbled 261.51%.
  • X4 Pharmaceuticals' Net Cash Flow stood at $5.5 million in 2021, then surged by 654.31% to $41.5 million in 2022, then plunged by 178.24% to -$32.5 million in 2023, then retreated by 27.7% to -$41.5 million in 2024, then jumped by 455.4% to $147.4 million in 2025.
  • Business Quant data shows XFOR's Net Cash Flow at $147.4 million in Q4 2025, $30.4 million in Q3 2025, and -$1.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Oculis Holding AG 65,899.61 Bn 65,899.33 Bn - 10.56 Mn
2 Nanobiotix 1,933.82 Bn 1,933.76 Bn - -
3 Akari Therapeutics 1,022.34 Bn 1,022.34 Bn - -2.44 Mn
4 BeOne Medicines 472.68 Bn 467.89 Bn 1.35 Bn 224.46 Mn
5 Vertex Pharmaceuticals 122.24 Bn 114.99 Bn 2.59 Bn 457.40 Mn
6 Regeneron Pharmaceuticals 70.08 Bn 61.33 Bn 3.31 Bn -152.20 Mn
7 Belite Bio 62.46 Bn 62.46 Bn - -
8 Argenx Se 55.93 Bn 50.75 Bn 1.41 Bn -
9 Alnylam Pharmaceuticals 37.59 Bn 34.58 Bn 959.66 Mn 60.68 Mn
10 X4 Pharmaceuticals 165.58 Mn -51.47 Mn 2.20 Mn 147.42 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 147.42 Mn
Dec 31, 2025 147.42 Mn
Sep 30, 2025 30.44 Mn
Sep 30, 2025 30.44 Mn
Jun 30, 2025 -1.19 Mn
Jun 30, 2025 -1.19 Mn
Mar 31, 2025 -15.51 Mn
Mar 31, 2025 -15.51 Mn
Dec 31, 2024 -41.48 Mn
Dec 31, 2024 -41.48 Mn
Sep 30, 2024 -49.96 Mn
Sep 30, 2024 -49.96 Mn
Jun 30, 2024 53.12 Mn
Jun 30, 2024 53.12 Mn
Mar 31, 2024 -38.92 Mn
Mar 31, 2024 -38.92 Mn
Dec 31, 2023 -32.48 Mn
Dec 31, 2023 -32.48 Mn
Sep 30, 2023 -52.75 Mn
Sep 30, 2023 -52.75 Mn