X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025)

X4 Pharmaceuticals' (XFOR) quarterly Net Cash Flow came in at $147.4 million in Q4 2025, up 455.4% YoY from $26.5 million in Q4 2024, and up 384.37% on a QoQ basis from $30.4 million in Q3 2025.

X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals (XFOR) has 9 years of Net Cash Flow data on file, last reported at $147.4 million in Q4 2025.

  • Quarterly Net Cash Flow rose 455.4% year-over-year to $147.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $161.2 million (up 308.65% YoY) and the FY2025 annual result came in at $161.2 million, up 469.5% from the prior year.
  • Net Cash Flow climbed to $147.4 million in Q4 2025, from $30.4 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $147.4 million in Q4 2025 to a low of -$52.8 million in Q3 2023.
  • A 5-year average of $1.5 million and a median of -$15.4 million in 2022 frame the typical range for Net Cash Flow.
  • Annual changes were most pronounced in 2022 — Net Cash Flow soared 654.31% — and 2023, when it plunged 261.51%.
  • Tracing XFOR's Net Cash Flow over 5 years: stood at $5.5 million in 2021, then soared by 654.31% to $41.5 million in 2022, then slumped by 178.24% to -$32.5 million in 2023, then declined by 27.7% to -$41.5 million in 2024, then surged by 455.4% to $147.4 million in 2025.
  • The last three Net Cash Flow figures came in at $147.4 million (Q4 2025), $30.4 million (Q3 2025), and -$1.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 X4 Pharmaceuticals 533.17 Mn 338.08 Mn 7.19 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 147.42 Mn
Dec 31, 2025 147.42 Mn
Sep 30, 2025 30.44 Mn
Sep 30, 2025 30.44 Mn
Jun 30, 2025 -1.19 Mn
Jun 30, 2025 -1.19 Mn
Mar 31, 2025 -15.51 Mn
Mar 31, 2025 -15.51 Mn
Dec 31, 2024 -41.48 Mn
Dec 31, 2024 -41.48 Mn
Sep 30, 2024 -49.96 Mn
Sep 30, 2024 -49.96 Mn
Jun 30, 2024 53.12 Mn
Jun 30, 2024 53.12 Mn
Mar 31, 2024 -38.92 Mn
Mar 31, 2024 -38.92 Mn
Dec 31, 2023 -32.48 Mn
Dec 31, 2023 -32.48 Mn
Sep 30, 2023 -52.75 Mn
Sep 30, 2023 -52.75 Mn