X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025)

X4 Pharmaceuticals (XFOR) reported Net Cash Flow of $147.4 million for Q4 2025, up 455.42% on a YoY basis from $26.5 million in Q4 2024, and up 384.26% quarter-over-quarter from $30.4 million in Q3 2025.

X4 Pharmaceuticals (XFOR) Net Cash Flow (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals has reported Net Cash Flow for 9 years, with the latest figure at $147.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Net Cash Flow rose 455.42% year-over-year to $147.4 million; the trailing twelve-month figure through Dec 2025 stood at $161.2 million (up 308.68% YoY), and the FY2025 full-year result was $161.2 million, up 469.54% from the prior year.
  • Net Cash Flow for Q4 2025 stood at $147.4 million, up from $30.4 million in the prior quarter.
  • The five-year high for Net Cash Flow was $147.4 million in Q4 2025, with the low at -$52.8 million in Q3 2023.
  • Historically, Net Cash Flow has averaged $1.5 million across 5 years, with a median of -$15.4 million in 2022.
  • Annual changes were most pronounced in 2022 — Net Cash Flow soared 654.31% — and 2023, when it plunged 261.51%.
  • X4 Pharmaceuticals' Net Cash Flow stood at $5.5 million in 2021, then soared by 654.31% to $41.5 million in 2022, then slumped by 178.24% to -$32.5 million in 2023, then declined by 27.7% to -$41.5 million in 2024, then surged by 455.42% to $147.4 million in 2025.
  • The last three Net Cash Flow figures came in at $147.4 million (Q4 2025), $30.4 million (Q3 2025), and -$1.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) NCF (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - 2.44 Mn
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn 625.70 Mn
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -2.44 Mn
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 457.40 Mn
9 Abivax 94.37 Bn 94.37 Bn - 664,983.53
10 X4 Pharmaceuticals 156.06 Mn 156.06 Mn 2.20 Mn 147.43 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 147.43 Mn
Dec 31, 2025 147.43 Mn
Sep 30, 2025 30.45 Mn
Sep 30, 2025 30.45 Mn
Jun 30, 2025 -1.16 Mn
Jun 30, 2025 -1.16 Mn
Mar 31, 2025 -15.54 Mn
Mar 31, 2025 -15.54 Mn
Dec 31, 2024 -41.48 Mn
Dec 31, 2024 -41.48 Mn
Sep 30, 2024 -49.96 Mn
Sep 30, 2024 -49.96 Mn
Jun 30, 2024 53.12 Mn
Jun 30, 2024 53.12 Mn
Mar 31, 2024 -38.92 Mn
Mar 31, 2024 -38.92 Mn
Dec 31, 2023 -32.48 Mn
Dec 31, 2023 -32.48 Mn
Sep 30, 2023 -52.75 Mn
Sep 30, 2023 -52.75 Mn