X4 Pharmaceuticals (XFOR) Free Cash Flow (2017 - 2025)

X4 Pharmaceuticals (XFOR) posted Free Cash Flow of -$15.5 million for Q4 2025, up 44.18% on a QoQ basis from -$27.8 million in Q3 2025, and up 53.03% year-over-year from -$10.1 million in Q4 2024.

X4 Pharmaceuticals (XFOR) Free Cash Flow (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals' Free Cash Flow history runs 9 years deep, the most recent figure standing at -$15.5 million for Q4 2025.

  • Quarterly Free Cash Flow rose 53.03% year-over-year to -$15.5 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$85.6 million (up 48.06% YoY) and the FY2025 annual result came in at -$85.6 million, up 34.76% from the prior year.
  • Free Cash Flow was -$15.5 million for Q4 2025 at X4 Pharmaceuticals, up from -$27.8 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$12.4 million in Q1 2025 and bottomed at -$68.8 million in Q3 2023.
  • A 5-year average of -$28.5 million and a median of -$23.4 million in 2022 frame the typical range for Free Cash Flow.
  • Annual changes were most pronounced in 2023 — Free Cash Flow sank 256.2% — and 2025, when it soared 63.25%.
  • X4 Pharmaceuticals' Free Cash Flow stood at -$19.1 million in 2021, then declined by 0.32% to -$19.1 million in 2022, then slumped by 45.07% to -$27.7 million in 2023, then declined by 19.06% to -$33.0 million in 2024, then jumped by 53.03% to -$15.5 million in 2025.
  • Business Quant data shows XFOR's Free Cash Flow at -$15.5 million in Q4 2025, -$27.8 million in Q3 2025, and -$29.9 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -19.58 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.49 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 158.09 Mn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -
9 Revolution Medicines 37.35 Bn 37.35 Bn - -354.95 Mn
10 X4 Pharmaceuticals 167.90 Mn -49.15 Mn 2.20 Mn -15.52 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -15.52 Mn
Dec 31, 2025 -15.52 Mn
Sep 30, 2025 -27.80 Mn
Sep 30, 2025 -27.80 Mn
Jun 30, 2025 -29.93 Mn
Jun 30, 2025 -29.93 Mn
Mar 31, 2025 -12.37 Mn
Mar 31, 2025 -12.37 Mn
Dec 31, 2024 -33.04 Mn
Dec 31, 2024 -33.04 Mn
Sep 30, 2024 -34.12 Mn
Sep 30, 2024 -34.12 Mn
Jun 30, 2024 -64.03 Mn
Jun 30, 2024 -64.03 Mn
Mar 31, 2024 -33.66 Mn
Mar 31, 2024 -33.66 Mn
Dec 31, 2023 -27.75 Mn
Dec 31, 2023 -27.75 Mn
Sep 30, 2023 -68.80 Mn
Sep 30, 2023 -68.80 Mn