X4 Pharmaceuticals (XFOR) Enterprise Value (2017 - 2025)

X4 Pharmaceuticals (XFOR) posted Enterprise Value of -$217.0 million for Q4 2025, down 211.71% on a QoQ basis from -$69.6 million in Q3 2025, and down 289.68% year-over-year from $114.4 million in Q4 2024.

X4 Pharmaceuticals (XFOR) Enterprise Value (2017 - 2025) Analysis & Trends

X4 Pharmaceuticals' Enterprise Value history runs 9 years deep, the most recent figure standing at -$217.0 million for Q4 2025.

  • Quarterly Enterprise Value fell 289.68% year-over-year to -$217.0 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$217.0 million (down 289.68% YoY) and the FY2025 annual result came in at -$217.0 million, down 289.68% from the prior year.
  • Enterprise Value was -$217.0 million for Q4 2025 at X4 Pharmaceuticals, down from -$69.6 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$39.2 million in Q2 2025 and bottomed at -$217.0 million in Q4 2025.
  • A 5-year average of -$93.6 million and a median of -$87.6 million in 2021 frame the typical range for Enterprise Value.
  • Peak annual rise in Enterprise Value reached 73.36% in 2025, while the deepest fall reached 289.68% in 2025.
  • X4 Pharmaceuticals' Enterprise Value stood at -$81.8 million in 2021, then sank by 48.82% to -$121.7 million in 2022, then increased by 18.49% to -$99.2 million in 2023, then surged by 43.86% to -$55.7 million in 2024, then sank by 289.68% to -$217.0 million in 2025.
  • Business Quant data shows XFOR's Enterprise Value at -$217.0 million in Q4 2025, -$69.6 million in Q3 2025, and -$39.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -283.54 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -61.40 Mn
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.83 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn -4.79 Bn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.35 Bn 37.35 Bn - -1.91 Bn
10 X4 Pharmaceuticals 167.90 Mn -49.15 Mn 2.20 Mn -217.05 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -217.05 Mn
Sep 30, 2025 -69.63 Mn
Jun 30, 2025 -39.22 Mn
Mar 31, 2025 -40.26 Mn
Dec 31, 2024 -55.70 Mn
Sep 30, 2024 -97.41 Mn
Jun 30, 2024 -147.22 Mn
Mar 31, 2024 -60.49 Mn
Dec 31, 2023 -99.22 Mn
Sep 30, 2023 -131.58 Mn
Jun 30, 2023 -136.43 Mn
Mar 31, 2023 -93.40 Mn
Dec 31, 2022 -121.72 Mn
Sep 30, 2022 -79.86 Mn
Jun 30, 2022 -47.38 Mn
Mar 31, 2022 -66.40 Mn
Dec 31, 2021 -81.79 Mn
Sep 30, 2021 -76.40 Mn
Jun 30, 2021 -95.20 Mn
Mar 31, 2021 -114.90 Mn