X4 Pharmaceuticals (XFOR) EBITDA Margin (2018 - 2025)

X4 Pharmaceuticals posted quarterly EBITDA Margin of 922.86% for Q4 2025, up 156773.0% year-on-year from N/an in Q4 2024, and up 40.79% on a QoQ basis from 1558.58% in Q3 2025.

X4 Pharmaceuticals (XFOR) has 4 years of EBITDA Margin data on file, last reported at 922.86% in Q4 2025.

  • For the quarter ending Q4 2025, EBITDA Margin rose 156773.0% year-over-year to 922.86%; the trailing twelve-month figure through Dec 2025 stood at 247.44% (up 117614.0% YoY), and the FY2025 full-year result was 247.44%, up 121729.0% from the prior year.
  • EBITDA Margin for Q4 2025 stood at 922.86%, up from 1558.58% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 12629.31% in Q2 2024 and bottomed at 6160.71% in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 X4 Pharmaceuticals 182.28 Mn 182.28 Mn 2.20 Mn -922.86%

Historic Data

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DateValue
Dec 31, 2025 -922.86%
Sep 30, 2025 -1,558.58%
Jun 30, 2025 -1,329.55%
Mar 31, 2025 -32.78%
Dec 31, 2024 -2,490.59%
Sep 30, 2024 -6,160.71%
Jun 30, 2024 12,629.31%
Mar 31, 2020 -371.27%
Dec 31, 2018 -230.11%