X4 Pharmaceuticals (XFOR) EBITDA Margin (2018 - 2025)

X4 Pharmaceuticals (XFOR) posted EBITDA Margin of 922.86% for Q4 2025, up 40.79% on a QoQ basis from 1558.58% in Q3 2025, and up 156773.0% year-over-year from N/an in Q4 2024.

X4 Pharmaceuticals (XFOR) EBITDA Margin (2018 - 2025) Analysis & Trends

X4 Pharmaceuticals' EBITDA Margin history runs 4 years deep, the most recent figure standing at 922.86% for Q4 2025.

  • Quarterly EBITDA Margin rose 156773.0% year-over-year to 922.86% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 247.44% (up 117614.0% YoY) and the FY2025 annual result came in at 247.44%, up 117614.0% from the prior year.
  • EBITDA Margin was 922.86% for Q4 2025 at X4 Pharmaceuticals, up from 1558.58% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 12629.31% in Q2 2024 and bottomed at 6160.71% in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 17.83%
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.35 Bn 37.35 Bn - -
10 X4 Pharmaceuticals 167.90 Mn -49.15 Mn 2.20 Mn -922.86%

Historic Data

Download Data
DateValue
Dec 31, 2025 -922.86%
Sep 30, 2025 -1,558.58%
Jun 30, 2025 -1,329.55%
Mar 31, 2025 -32.78%
Dec 31, 2024 -2,490.59%
Sep 30, 2024 -6,160.71%
Jun 30, 2024 12,629.31%
Mar 31, 2020 -352.70%
Dec 31, 2018 -230.11%