X4 Pharmaceuticals (XFOR) Change in Cash (2017 - 2025)
X4 Pharmaceuticals posted quarterly Change in Cash of $147.4 million for Q4 2025, up 453.31% year-on-year from $26.6 million in Q4 2024, and up 384.72% on a QoQ basis from $30.4 million in Q3 2025.
X4 Pharmaceuticals (XFOR) has 9 years of Change in Cash data on file, last reported at $147.4 million in Q4 2025.
- For the quarter ending Q4 2025, Change in Cash rose 453.31% year-over-year to $147.4 million; the trailing twelve-month figure through Dec 2025 stood at $161.4 million (up 468.67% YoY), and the FY2025 full-year result was $161.4 million, up 468.67% from the prior year.
- Change in Cash for Q4 2025 stood at $147.4 million, up from $30.4 million in the prior quarter.
- Across five years, Change in Cash topped out at $147.4 million in Q4 2025 and bottomed at -$49.8 million in Q3 2024.
- The 5-year median for Change in Cash is -$10.1 million (2022), against an average of $6.9 million.
- The widest annual swing landed in 2022, when Change in Cash jumped 677.28%; it then tumbled 926.3% in 2024.
- A 5-year view of Change in Cash shows it stood at $5.4 million in 2021, then surged by 677.28% to $41.9 million in 2022, then plunged by 177.26% to -$32.4 million in 2023, then declined by 28.96% to -$41.7 million in 2024, then surged by 453.31% to $147.4 million in 2025.
- The last three Change in Cash figures came in at $147.4 million (Q4 2025), $30.4 million (Q3 2025), and -$1.0 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 623.00 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 417.10 Mn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | -153.10 Mn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 53.61 Mn |
| 10 | X4 Pharmaceuticals | 182.28 Mn | 182.28 Mn | 2.20 Mn | 147.42 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 147.42 Mn |
| Sep 30, 2025 | 30.41 Mn |
| Jun 30, 2025 | -1.02 Mn |
| Mar 31, 2025 | -15.43 Mn |
| Dec 31, 2024 | -41.73 Mn |
| Sep 30, 2024 | -49.80 Mn |
| Jun 30, 2024 | 86.73 Mn |
| Mar 31, 2024 | -38.98 Mn |
| Dec 31, 2023 | -32.36 Mn |
| Sep 30, 2023 | -4.85 Mn |
| Jun 30, 2023 | 43.02 Mn |
| Mar 31, 2023 | -28.60 Mn |
| Dec 31, 2022 | 41.88 Mn |
| Sep 30, 2022 | 32.47 Mn |
| Jun 30, 2022 | -19.06 Mn |
| Mar 31, 2022 | -15.36 Mn |
| Dec 31, 2021 | 5.39 Mn |
| Sep 30, 2021 | -18.77 Mn |
| Jun 30, 2021 | -20.17 Mn |
| Mar 31, 2021 | 35.96 Mn |
| Dec 31, 2020 | -10.02 Mn |
| Sep 30, 2020 | -14.93 Mn |
| Jun 30, 2020 | -11.31 Mn |
| Mar 31, 2020 | -11.13 Mn |
| Dec 31, 2019 | 51.08 Mn |
| Sep 30, 2019 | -18.64 Mn |
| Jun 30, 2019 | 72.40 Mn |
| Mar 31, 2019 | 14.75 Mn |
| Dec 31, 2018 | -1.71 Mn |
| Sep 30, 2018 | -2.73 Mn |
| Jun 30, 2018 | -6.28 Mn |
| Mar 31, 2018 | -7.84 Mn |
| Dec 31, 2017 | -16.56 Mn |
| Sep 30, 2017 | -1.12 Mn |
| Jun 30, 2017 | 28.60 Mn |
| Mar 31, 2017 | 820,000.00 |