X4 Pharmaceuticals (XFOR) Change in Cash (2017 - 2025)
X4 Pharmaceuticals (XFOR) posted Change in Cash of $147.4 million for Q4 2025, up 384.72% on a QoQ basis from $30.4 million in Q3 2025, and up 453.31% year-over-year from $26.6 million in Q4 2024.
X4 Pharmaceuticals (XFOR) Change in Cash (2017 - 2025) Analysis & Trends
X4 Pharmaceuticals' Change in Cash history runs 9 years deep, the most recent figure standing at $147.4 million for Q4 2025.
- Quarterly Change in Cash rose 453.31% year-over-year to $147.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was $161.4 million (up 468.67% YoY) and the FY2025 annual result came in at $161.4 million, up 468.67% from the prior year.
- Change in Cash was $147.4 million for Q4 2025 at X4 Pharmaceuticals, up from $30.4 million in the prior quarter.
- Across five years, Change in Cash topped out at $147.4 million in Q4 2025 and bottomed at -$49.8 million in Q3 2024.
- A 5-year average of $6.9 million and a median of -$10.1 million in 2022 frame the typical range for Change in Cash.
- Annual changes were most pronounced in 2022 — Change in Cash jumped 677.28% — and 2024, when it plunged 926.3%.
- X4 Pharmaceuticals' Change in Cash stood at $5.4 million in 2021, then soared by 677.28% to $41.9 million in 2022, then tumbled by 177.26% to -$32.4 million in 2023, then fell by 28.96% to -$41.7 million in 2024, then soared by 453.31% to $147.4 million in 2025.
- Business Quant data shows XFOR's Change in Cash at $147.4 million in Q4 2025, $30.4 million in Q3 2025, and -$1.0 million in Q2 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 66,621.14 Bn | 66,620.85 Bn | - | -22.03 Mn |
| 2 | Nanobiotix | 1,915.18 Bn | 1,915.11 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -2.44 Mn |
| 4 | BeOne Medicines | 471.27 Bn | 466.48 Bn | 1.35 Bn | 243.78 Mn |
| 5 | Vertex Pharmaceuticals | 121.81 Bn | 114.57 Bn | 2.59 Bn | 417.10 Mn |
| 6 | Regeneron Pharmaceuticals | 69.58 Bn | 60.82 Bn | 3.31 Bn | -153.10 Mn |
| 7 | Belite Bio | 62.72 Bn | 62.72 Bn | - | - |
| 8 | Argenx Se | 55.51 Bn | 50.33 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.35 Bn | 37.35 Bn | - | 57.19 Mn |
| 10 | X4 Pharmaceuticals | 167.90 Mn | -49.15 Mn | 2.20 Mn | 147.42 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 147.42 Mn |
| Sep 30, 2025 | 30.41 Mn |
| Jun 30, 2025 | -1.02 Mn |
| Mar 31, 2025 | -15.43 Mn |
| Dec 31, 2024 | -41.73 Mn |
| Sep 30, 2024 | -49.80 Mn |
| Jun 30, 2024 | 86.73 Mn |
| Mar 31, 2024 | -38.98 Mn |
| Dec 31, 2023 | -32.36 Mn |
| Sep 30, 2023 | -4.85 Mn |
| Jun 30, 2023 | 43.02 Mn |
| Mar 31, 2023 | -28.60 Mn |
| Dec 31, 2022 | 41.88 Mn |
| Sep 30, 2022 | 32.47 Mn |
| Jun 30, 2022 | -19.06 Mn |
| Mar 31, 2022 | -15.36 Mn |
| Dec 31, 2021 | 5.39 Mn |
| Sep 30, 2021 | -18.77 Mn |
| Jun 30, 2021 | -20.17 Mn |
| Mar 31, 2021 | 35.96 Mn |