Xeris Biopharma Holdings (XERS) Net Margin (2020 - 2026)

Xeris Biopharma Holdings (XERS) reported Net Margin of 2.69% for Q1 2026, up 1802.0% on a YoY basis from 0.14% in Q1 2025, and down 79.19% quarter-over-quarter from 12.91% in Q4 2025.

Xeris Biopharma Holdings (XERS) Net Margin (2020 - 2026) Analysis & Trends

Xeris Biopharma Holdings has reported Net Margin for 7 years, with the latest figure at 2.69% in Q1 2026.

  • For the quarter ending Q1 2026, Net Margin rose 1802.0% year-over-year to 2.69%; the trailing twelve-month figure through Mar 2026 stood at 3.81% (up 2407.0% YoY), and the FY2025 full-year result was 0.19%, up 2719.0% from the prior year.
  • Net Margin for Q1 2026 stood at 2.69%, down from 12.91% in the prior quarter.
  • The five-year high for Net Margin was 12.91% in Q4 2025, with the low at 152.74% in Q1 2022.
  • Historically, Net Margin has averaged 37.88% across 5 years, with a median of 30.16% in 2023.
  • Annual changes were most pronounced in 2022 — Net Margin surged 20548 bps — and 2024, when it sank 377 bps.
  • Xeris Biopharma Holdings' Net Margin stood at 39.01% in 2022, then rose by 23 bps to 30.16% in 2023, then jumped by 72 bps to 8.51% in 2024, then jumped by 252 bps to 12.91% in 2025, then slumped by 79 bps to 2.69% in 2026.
  • The last three Net Margin figures came in at 2.69% (Q1 2026), 12.91% (Q4 2025), and 0.83% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn 9.19%
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn 26.57%
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn 35.18%
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn 2.94%
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn 24.30%
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn 4.16%
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn -168.42%
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -15.15%
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn 31.38%
10 Xeris Biopharma Holdings 1.11 Bn 994.95 Mn 72.55 Mn 2.69%

Historic Data

Download Data
DateValue
Mar 31, 2026 2.69%
Dec 31, 2025 12.91%
Sep 30, 2025 0.83%
Jun 30, 2025 -2.70%
Mar 31, 2025 -15.34%
Dec 31, 2024 -8.51%
Sep 30, 2024 -29.00%
Jun 30, 2024 -31.22%
Mar 31, 2024 -46.71%
Dec 31, 2023 -30.16%
Sep 30, 2023 -25.23%
Jun 30, 2023 -52.20%
Mar 31, 2023 -50.71%
Dec 31, 2022 -39.01%
Sep 30, 2022 -73.44%
Jun 30, 2022 -103.47%
Mar 31, 2022 -152.74%
Dec 31, 2021 -237.02%
Sep 30, 2021 -235.16%
Jun 30, 2021 -308.95%