Xeris Biopharma Holdings (XERS) Net Margin (2020 - 2026)
Xeris Biopharma Holdings (XERS) posted Net Margin of -33.77% for Q2 2026, down 31.07 percentage points from -2.70% a year earlier and down 36.46 percentage points from the prior quarter.
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Analysis
Xeris Biopharma Holdings (XERS) Net Margin (2020 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at Xeris Biopharma Holdings was -5.12%, up 7.89 percentage points year-over-year; for FY2025, it came in at 0.19%, up 27.19 percentage points from FY2024.
- Annual Net Margin has increased for five consecutive years, with a five-year change of +446.19 percentage points (FY2020 to FY2025).
- In prior years, Xeris Biopharma Holdings' Net Margin was -27.00% in FY2024 (+10.98 pp), -37.98% in FY2023 (+47.88 pp), -85.86% in FY2022 (+161.62 pp) and -247.48% in FY2021 (+198.52 pp).
- The Q2 2026 figure stands as the lowest quarterly Net Margin since Q1 2024.
- On a year-over-year basis, Net Margin increased in six of the last eight quarters, with an average year-over-year change of +14.50 percentage points.
- The strongest year-over-year quarter for Net Margin in the past five years was Q2 2022, with a gain of 205.48 percentage points; the weakest was Q3 2021, with a drop of 65.02 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was 2.69% (Q1 2026), 12.91% (Q4 2025) and 0.83% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Xeris Biopharma Holdings | 1.71 Bn | 1.27 Bn | 79.59 Mn | -33.77% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -33.77% |
| Mar 31, 2026 | 2.69% |
| Dec 31, 2025 | 12.91% |
| Sep 30, 2025 | 0.83% |
| Jun 30, 2025 | -2.70% |
| Mar 31, 2025 | -15.34% |
| Dec 31, 2024 | -8.51% |
| Sep 30, 2024 | -29.00% |
| Jun 30, 2024 | -31.22% |
| Mar 31, 2024 | -46.71% |
| Dec 31, 2023 | -30.16% |
| Sep 30, 2023 | -25.23% |
| Jun 30, 2023 | -52.20% |
| Mar 31, 2023 | -50.71% |
| Dec 31, 2022 | -39.01% |
| Sep 30, 2022 | -73.44% |
| Jun 30, 2022 | -103.47% |
| Mar 31, 2022 | -152.74% |
| Dec 31, 2021 | -237.02% |
| Sep 30, 2021 | -235.16% |
API Access
Xeris Biopharma Holdings Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=XERS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "XERS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();