Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026)
Xeris Biopharma Holdings (XERS) reported EBITDA Margin of 9.89% for Q2 2026, down 1.74 percentage points from 11.63% a year earlier and down 4.38 percentage points from the prior quarter.
Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Xeris Biopharma Holdings' EBITDA Margin came in at 15.58%, up 13.33 percentage points year-over-year; for FY2025, it was 13.86%, up 23.00 percentage points from FY2024.
- EBITDA Margin has increased for five consecutive years, with a five-year change of +410.72 percentage points (FY2020 to FY2025).
- By year, EBITDA Margin came in at -9.14% in FY2024 (+8.84 pp), -17.98% in FY2023 (+43.79 pp), -61.77% in FY2022 (+164.64 pp) and -226.41% in FY2021 (+170.45 pp).
- The Q2 2026 figure ranks as the lowest quarterly EBITDA Margin since Q1 2025.
- Year over year, EBITDA Margin gained in six of the last eight quarters, with an average year-over-year change of +14.30 percentage points.
- The high point for year-over-year EBITDA Margin in five years was Q2 2022 (a gain of 222.57 percentage points); the low point was Q3 2024 (a drop of 14.22 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 14.27% (Q1 2026), 24.14% (Q4 2025) and 14.22% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 36.69% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 40.60% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 39.77% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 46.62% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 42.49% |
| 10 | Xeris Biopharma Holdings | 2.89 Bn | 2.41 Bn | 94.80 Mn | 19.43% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 19.43% |
| Jun 30, 2026 | 9.89% |
| Mar 31, 2026 | 14.27% |
| Dec 31, 2025 | 24.11% |
| Sep 30, 2025 | 14.17% |
| Jun 30, 2025 | 11.63% |
| Mar 31, 2025 | 1.30% |
| Dec 31, 2024 | 9.17% |
| Sep 30, 2024 | -16.72% |
| Jun 30, 2024 | -9.15% |
| Mar 31, 2024 | -26.10% |
| Dec 31, 2023 | -14.15% |
| Sep 30, 2023 | -2.51% |
| Jun 30, 2023 | -32.32% |
| Mar 31, 2023 | -29.08% |
| Dec 31, 2022 | -35.01% |
| Sep 30, 2022 | -51.50% |
| Jun 30, 2022 | -60.67% |
| Mar 31, 2022 | -116.99% |
| Dec 31, 2021 | -219.79% |
Xeris Biopharma Holdings EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "XERS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();