Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026)
Xeris Biopharma Holdings (XERS) reported EBITDA Margin of 8.91% for Q2 2026, down 1.60 percentage points from 10.51% a year earlier and down 4.28 percentage points from the prior quarter.
Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Xeris Biopharma Holdings' EBITDA Margin came in at 14.54%, up 13.61 percentage points year-over-year; for FY2025, it was 12.70%, up 23.32 percentage points from FY2024.
- EBITDA Margin has increased for five consecutive years, with a five-year change of +414.35 percentage points (FY2020 to FY2025).
- By year, EBITDA Margin came in at -10.62% in FY2024 (+8.70 pp), -19.33% in FY2023 (+43.89 pp), -63.22% in FY2022 (+165.21 pp) and -228.43% in FY2021 (+173.23 pp).
- The Q2 2026 figure ranks as the lowest quarterly EBITDA Margin since Q1 2025.
- Year over year, EBITDA Margin gained in six of the last eight quarters, with an average year-over-year change of +14.47 percentage points.
- The high point for year-over-year EBITDA Margin in five years was Q2 2022 (a gain of 223.30 percentage points); the low point was Q3 2024 (a drop of 14.45 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 13.19% (Q1 2026), 23.10% (Q4 2025) and 13.15% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Xeris Biopharma Holdings | 1.71 Bn | 1.27 Bn | 79.59 Mn | 8.91% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 8.91% |
| Mar 31, 2026 | 13.19% |
| Dec 31, 2025 | 23.10% |
| Sep 30, 2025 | 13.15% |
| Jun 30, 2025 | 10.51% |
| Mar 31, 2025 | -0.11% |
| Dec 31, 2024 | 7.83% |
| Sep 30, 2024 | -18.20% |
| Jun 30, 2024 | -10.81% |
| Mar 31, 2024 | -27.58% |
| Dec 31, 2023 | -15.28% |
| Sep 30, 2023 | -3.75% |
| Jun 30, 2023 | -33.90% |
| Mar 31, 2023 | -30.73% |
| Dec 31, 2022 | -36.48% |
| Sep 30, 2022 | -52.85% |
| Jun 30, 2022 | -62.65% |
| Mar 31, 2022 | -117.98% |
| Dec 31, 2021 | -221.06% |
| Sep 30, 2021 | -217.31% |
Xeris Biopharma Holdings EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "XERS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();