Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026)
Xeris Biopharma Holdings (XERS) reported EBITDA Margin of 8.91% for Q2 2026, down 1.60 percentage points from 10.51% a year earlier and down 4.28 percentage points from the prior quarter.
Powered by 
Analysis
Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Xeris Biopharma Holdings' EBITDA Margin came in at 14.54%, up 13.61 percentage points year-over-year; for FY2025, it was 12.70%, up 23.32 percentage points from FY2024.
- EBITDA Margin has increased for five consecutive years, with a five-year change of +414.35 percentage points (FY2020 to FY2025).
- By year, EBITDA Margin came in at -10.62% in FY2024 (+8.70 pp), -19.33% in FY2023 (+43.89 pp), -63.22% in FY2022 (+165.21 pp) and -228.43% in FY2021 (+173.23 pp).
- The Q2 2026 figure ranks as the lowest quarterly EBITDA Margin since Q1 2025.
- Year over year, EBITDA Margin gained in six of the last eight quarters, with an average year-over-year change of +14.47 percentage points.
- The high point for year-over-year EBITDA Margin in five years was Q2 2022 (a gain of 223.30 percentage points); the low point was Q3 2024 (a drop of 14.45 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at 13.19% (Q1 2026), 23.10% (Q4 2025) and 13.15% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,137.42 Bn | 1,106.00 Bn | 19.71 Bn | 53.49% |
| 2 | Johnson & Johnson | 617.98 Bn | 536.51 Bn | 17.26 Bn | 35.95% |
| 3 | AbbVie | 502.80 Bn | 475.92 Bn | 12.70 Bn | 49.01% |
| 4 | Merck | 368.67 Bn | 323.05 Bn | 12.21 Bn | 6.02% |
| 5 | Novartis Ag | 298.36 Bn | 262.35 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 261.17 Bn | 234.85 Bn | 12.86 Bn | 33.11% |
| 7 | Amgen | 237.18 Bn | 192.58 Bn | 7.24 Bn | 46.01% |
| 8 | Gilead Sciences | 191.11 Bn | 165.31 Bn | 6.22 Bn | -124.26% |
| 9 | Pfizer | 169.83 Bn | 116.48 Bn | 10.94 Bn | 39.16% |
| 10 | Xeris Biopharma Holdings | 1.88 Bn | 1.45 Bn | 79.59 Mn | 9.89% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 9.89% |
| Mar 31, 2026 | 14.27% |
| Dec 31, 2025 | 24.14% |
| Sep 30, 2025 | 14.22% |
| Jun 30, 2025 | 11.63% |
| Mar 31, 2025 | 1.30% |
| Dec 31, 2024 | 9.17% |
| Sep 30, 2024 | -16.72% |
| Jun 30, 2024 | -9.15% |
| Mar 31, 2024 | -26.10% |
| Dec 31, 2023 | -14.15% |
| Sep 30, 2023 | -2.51% |
| Jun 30, 2023 | -32.32% |
| Mar 31, 2023 | -29.08% |
| Dec 31, 2022 | -35.01% |
| Sep 30, 2022 | -51.50% |
| Jun 30, 2022 | -60.67% |
| Mar 31, 2022 | -116.99% |
| Dec 31, 2021 | -219.79% |
| Sep 30, 2021 | -215.19% |
API Access
Xeris Biopharma Holdings EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "XERS", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=XERS&period=max&api_key=YOUR_API_KEY");
const data = await res.json();