Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026)

Xeris Biopharma Holdings (XERS) reported EBITDA Margin of 2.69% for Q1 2026, up 1802.0% on a YoY basis from 0.14% in Q1 2025, and down 79.18% quarter-over-quarter from 12.91% in Q4 2025.

Xeris Biopharma Holdings (XERS) EBITDA Margin (2020 - 2026) Analysis & Trends

Xeris Biopharma Holdings has reported EBITDA Margin for 7 years, with the latest figure at 2.69% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin rose 1802.0% year-over-year to 2.69%; the trailing twelve-month figure through Mar 2026 stood at 3.81% (up 2406.0% YoY), and the FY2025 full-year result was 0.19%, up 2719.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 2.69%, down from 12.91% in the prior quarter.
  • The five-year high for EBITDA Margin was 12.91% in Q4 2025, with the low at 152.9% in Q1 2022.
  • Historically, EBITDA Margin has averaged 37.88% across 5 years, with a median of 30.11% in 2023.
  • Annual changes were most pronounced in 2022 — EBITDA Margin jumped 20564 bps — and 2024, when it plunged 381 bps.
  • Xeris Biopharma Holdings' EBITDA Margin stood at 38.97% in 2022, then advanced by 23 bps to 30.11% in 2023, then surged by 72 bps to 8.52% in 2024, then soared by 252 bps to 12.91% in 2025, then sank by 79 bps to 2.69% in 2026.
  • The last three EBITDA Margin figures came in at 2.69% (Q1 2026), 12.91% (Q4 2025), and 0.83% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Teva Pharmaceutical Industries 39.72 Bn 35.98 Bn 1.97 Bn 16.37%
2 Zoetis 34.61 Bn 32.67 Bn 1.62 Bn 36.83%
3 United Therapeutics 24.07 Bn 21.91 Bn 648.10 Mn 41.69%
4 Aurora Cannabis 16.98 Bn 16.91 Bn 33.43 Mn -1.01%
5 Neurocrine Biosciences 16.64 Bn 15.32 Bn 800.70 Mn 22.74%
6 Elanco Animal Health 12.19 Bn 11.76 Bn 785.00 Mn 22.39%
7 Alkermes 7.37 Bn 6.86 Bn -116.06 Mn -170.35%
8 Hims & Hers Health 6.62 Bn 5.87 Bn 396.79 Mn -16.25%
9 Lantheus Holdings 6.47 Bn 5.97 Bn 230.92 Mn 21.55%
10 Xeris Biopharma Holdings 1.11 Bn 994.95 Mn 72.55 Mn 2.69%

Historic Data

Download Data
DateValue
Mar 31, 2026 2.69%
Dec 31, 2025 12.91%
Sep 30, 2025 0.83%
Jun 30, 2025 -2.69%
Mar 31, 2025 -15.34%
Dec 31, 2024 -8.52%
Sep 30, 2024 -28.97%
Jun 30, 2024 -31.21%
Mar 31, 2024 -46.73%
Dec 31, 2023 -30.11%
Sep 30, 2023 -25.17%
Jun 30, 2023 -52.33%
Mar 31, 2023 -50.73%
Dec 31, 2022 -38.97%
Sep 30, 2022 -73.39%
Jun 30, 2022 -103.42%
Mar 31, 2022 -152.90%
Dec 31, 2021 -237.04%
Sep 30, 2021 -235.22%
Jun 30, 2021 -309.06%