Xenon Pharmaceuticals (XENE) Return on Equity [ROE] (2014 - 2026)
Xenon Pharmaceuticals' Return on Equity [ROE] was -31.72% in Q2 2026, up 9.87 percentage points from -41.59% a year earlier and up 8.20 percentage points from the prior quarter.
Xenon Pharmaceuticals (XENE) Return on Equity [ROE] (2014 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Xenon Pharmaceuticals came in at -51.76%, down 23.91 percentage points from FY2024.
- Return on Equity [ROE] has now declined for three consecutive years, with a five-year change of -29.86 percentage points (FY2020 to FY2025).
- In earlier years, Return on Equity [ROE] was -27.85% in FY2024 (-5.73 pp), -22.12% in FY2023 (-2.40 pp), -19.72% in FY2022 (+2.15 pp) and -21.87% in FY2021 (+0.03 pp).
- The Q2 2026 figure marks the highest quarterly Return on Equity [ROE] since Q4 2024.
- Compared with a year earlier, Return on Equity [ROE] was higher in two of the last eight quarters, with an average year-over-year change of -11.15 percentage points.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q3 2022 (a gain of 11.19 percentage points); the worst was Q4 2025 (a drop of 30.44 percentage points).
- Per Business Quant data, XENE's Return on Equity [ROE] in the three quarters before Q2 2026 was -39.92% (Q1 2026), -60.62% (Q4 2025) and -51.33% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Xenon Pharmaceuticals | 4.07 Bn | 542.89 Mn | - | -36.36% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -36.36% |
| Jun 30, 2026 | -31.93% |
| Mar 31, 2026 | -39.96% |
| Dec 31, 2025 | -60.28% |
| Sep 30, 2025 | -51.48% |
| Jun 30, 2025 | -41.24% |
| Mar 31, 2025 | -34.34% |
| Dec 31, 2024 | -30.38% |
| Sep 30, 2024 | -25.47% |
| Jun 30, 2024 | -22.86% |
| Mar 31, 2024 | -20.77% |
| Dec 31, 2023 | -22.94% |
| Sep 30, 2023 | -27.29% |
| Jun 30, 2023 | -24.91% |
| Mar 31, 2023 | -21.05% |
| Dec 31, 2022 | -17.28% |
| Sep 30, 2022 | -15.01% |
| Jun 30, 2022 | -13.83% |
| Mar 31, 2022 | -15.16% |
| Dec 31, 2021 | -19.75% |
Xenon Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XENE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XENE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XENE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();