Xenon Pharmaceuticals (XENE) Return on Equity [ROE] (2014 - 2026)
Xenon Pharmaceuticals' Return on Equity [ROE] was -31.72% in Q2 2026, up 9.87 percentage points from -41.59% a year earlier and up 8.20 percentage points from the prior quarter.
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Analysis
Xenon Pharmaceuticals (XENE) Return on Equity [ROE] (2014 - 2026) Analysis & Trends
For FY2025, Return on Equity [ROE] at Xenon Pharmaceuticals came in at -51.76%, down 23.91 percentage points from FY2024.
- Return on Equity [ROE] has now declined for three consecutive years, with a five-year change of -29.86 percentage points (FY2020 to FY2025).
- In earlier years, Return on Equity [ROE] was -27.85% in FY2024 (-5.73 pp), -22.12% in FY2023 (-2.40 pp), -19.72% in FY2022 (+2.15 pp) and -21.87% in FY2021 (+0.03 pp).
- The Q2 2026 figure marks the highest quarterly Return on Equity [ROE] since Q4 2024.
- Compared with a year earlier, Return on Equity [ROE] was higher in two of the last eight quarters, with an average year-over-year change of -11.15 percentage points.
- The best year-over-year quarter for Return on Equity [ROE] over five years was Q3 2022 (a gain of 11.19 percentage points); the worst was Q4 2025 (a drop of 30.44 percentage points).
- Per Business Quant data, XENE's Return on Equity [ROE] in the three quarters before Q2 2026 was -39.92% (Q1 2026), -60.62% (Q4 2025) and -51.33% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Xenon Pharmaceuticals | 3.60 Bn | 3.60 Bn | - | -31.72% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -31.72% |
| Mar 31, 2026 | -39.92% |
| Dec 31, 2025 | -60.62% |
| Sep 30, 2025 | -51.33% |
| Jun 30, 2025 | -41.59% |
| Mar 31, 2025 | -34.47% |
| Dec 31, 2024 | -30.18% |
| Sep 30, 2024 | -25.99% |
| Jun 30, 2024 | -22.99% |
| Mar 31, 2024 | -20.77% |
| Dec 31, 2023 | -23.32% |
| Sep 30, 2023 | -27.29% |
| Jun 30, 2023 | -24.56% |
| Mar 31, 2023 | -20.94% |
| Dec 31, 2022 | -17.00% |
| Sep 30, 2022 | -14.76% |
| Jun 30, 2022 | -13.83% |
| Mar 31, 2022 | -15.16% |
| Dec 31, 2021 | -19.75% |
| Sep 30, 2021 | -25.95% |
API Access
Xenon Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XENE&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "XENE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=XENE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();