Xenon Pharmaceuticals (XENE) Operating Income (2013 - 2026)
Xenon Pharmaceuticals' (XENE) quarterly Operating Income came in at -$112.3 million in Q1 2026, down 54.43% year-on-year from -$246.5 million in Q1 2025, and down 2.33% on a QoQ basis from -$109.8 million in Q4 2025.
Xenon Pharmaceuticals (XENE) Operating Income (2013 - 2026) Analysis & Trends
Xenon Pharmaceuticals (XENE) has 14 years of Operating Income data on file, last reported at -$112.3 million in Q1 2026.
- On a quarterly basis, Operating Income fell 54.43% year-over-year to -$112.3 million in Q1 2026; TTM through Mar 2026 was -$412.7 million, a 40.84% decrease from a year earlier, with the FY2025 full-year figure at -$373.1 million, down 33.57% from the prior year.
- Operating Income for Q1 2026 stood at -$112.3 million, down from -$109.8 million in the prior quarter.
- Over the last five years, Operating Income for XENE reached as high as -$17.4 million in Q1 2022 and fell as low as -$112.3 million in Q1 2026.
- Historically, Operating Income has averaged -$65.2 million across 5 years, with a median of -$59.0 million in 2024.
- Across the five-year window, Operating Income slipped 8.16% in 2022 and plunged 182.41% in 2023, its largest moves.
- Year by year, Operating Income stood at -$43.3 million in 2022, then dropped by 23.92% to -$53.7 million in 2023, then tumbled by 44.29% to -$77.5 million in 2024, then tumbled by 41.68% to -$109.8 million in 2025, then retreated by 2.33% to -$112.3 million in 2026.
- Per Business Quant data, the three most recent Operating Income figures were -$112.3 million in Q1 2026, -$109.8 million in Q4 2025, and -$96.3 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Xenon Pharmaceuticals | 5.71 Bn | 5.71 Bn | - | -112.33 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -112.33 Mn |
| Dec 31, 2025 | -109.77 Mn |
| Sep 30, 2025 | -96.34 Mn |
| Jun 30, 2025 | -94.23 Mn |
| Mar 31, 2025 | -72.74 Mn |
| Dec 31, 2024 | -77.48 Mn |
| Sep 30, 2024 | -73.68 Mn |
| Jun 30, 2024 | -69.10 Mn |
| Mar 31, 2024 | -59.04 Mn |
| Dec 31, 2023 | -53.70 Mn |
| Sep 30, 2023 | -55.68 Mn |
| Jun 30, 2023 | -55.62 Mn |
| Mar 31, 2023 | -49.05 Mn |
| Dec 31, 2022 | -43.33 Mn |
| Sep 30, 2022 | -38.13 Mn |
| Jun 30, 2022 | -30.32 Mn |
| Mar 31, 2022 | -17.37 Mn |
| Dec 31, 2021 | -24.84 Mn |
| Sep 30, 2021 | -15.60 Mn |
| Jun 30, 2021 | -22.50 Mn |