Wave Life Sciences (WVE) Operating Income (2014 - 2026)

Wave Life Sciences (WVE) posted Operating Income of -$31.3 million for Q1 2026, up 44.57% on a QoQ basis from -$56.5 million in Q4 2025, and up 37.16% year-over-year from -$22.8 million in Q1 2025.

Wave Life Sciences (WVE) Operating Income (2014 - 2026) Analysis & Trends

Wave Life Sciences' Operating Income history runs 13 years deep, the most recent figure standing at -$31.3 million for Q1 2026.

  • Quarterly Operating Income rose 37.16% year-over-year to -$31.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$196.9 million (down 56.56% YoY) and the FY2025 annual result came in at -$215.4 million, down 95.09% from the prior year.
  • Operating Income was -$31.3 million for Q1 2026 at Wave Life Sciences, up from -$56.5 million in the prior quarter.
  • Across five years, Operating Income topped out at $23.0 million in Q4 2024 and bottomed at -$63.9 million in Q3 2024.
  • A 5-year average of -$34.6 million and a median of -$38.1 million in 2022 frame the typical range for Operating Income.
  • Peak annual rise in Operating Income reached 222.94% in 2024, while the deepest fall reached 1538.23% in 2024.
  • Wave Life Sciences' Operating Income stood at -$43.6 million in 2022, then soared by 57.11% to -$18.7 million in 2023, then soared by 222.94% to $23.0 million in 2024, then plunged by 345.86% to -$56.5 million in 2025, then surged by 44.57% to -$31.3 million in 2026.
  • Business Quant data shows WVE's Operating Income at -$31.3 million in Q1 2026, -$56.5 million in Q4 2025, and -$56.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Wave Life Sciences 1.16 Bn 612.38 Mn - -31.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -31.30 Mn
Dec 31, 2025 -56.47 Mn
Sep 30, 2025 -56.35 Mn
Jun 30, 2025 -52.76 Mn
Mar 31, 2025 -49.80 Mn
Dec 31, 2024 22.97 Mn
Sep 30, 2024 -63.92 Mn
Jun 30, 2024 -35.00 Mn
Mar 31, 2024 -34.46 Mn
Dec 31, 2023 -18.68 Mn
Sep 30, 2023 4.44 Mn
Jun 30, 2023 -23.47 Mn
Mar 31, 2023 -30.29 Mn
Dec 31, 2022 -43.56 Mn
Sep 30, 2022 -38.90 Mn
Jun 30, 2022 -42.16 Mn
Mar 31, 2022 -38.09 Mn
Dec 31, 2021 -36.11 Mn
Sep 30, 2021 -7.61 Mn
Jun 30, 2021 -39.83 Mn