Growth Metrics

Wave Life Sciences (WVE) Change in Cash (2014 - 2026)

Wave Life Sciences posted quarterly Change in Cash of -$57.5 million for Q1 2026, up 2.58% year-on-year from -$56.0 million in Q1 2025, and down 114.16% on a QoQ basis from $405.9 million in Q4 2025.

Wave Life Sciences (WVE) has 13 years of Change in Cash data on file, last reported at -$57.5 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Cash rose 2.58% year-over-year to -$57.5 million; the trailing twelve-month figure through Mar 2026 stood at $301.6 million (up 384.74% YoY), and the FY2025 full-year result was $300.0 million, up 194.77% from the prior year.
  • Change in Cash for Q1 2026 stood at -$57.5 million, down from $405.9 million in the prior quarter.
  • Across five years, Change in Cash topped out at $405.9 million in Q4 2025 and bottomed at -$88.9 million in Q1 2022.
  • The 5-year median for Change in Cash is -$19.4 million (2024), against an average of $23.2 million.
  • Peak annual rise in Change in Cash reached 4682.88% in 2025, while the deepest fall reached 203.87% in 2025.
  • A 5-year view of Change in Cash shows it stood at -$8.5 million in 2022, then jumped by 815.0% to $60.4 million in 2023, then plunged by 114.66% to -$8.9 million in 2024, then jumped by 4682.88% to $405.9 million in 2025, then tumbled by 114.16% to -$57.5 million in 2026.
  • The last three Change in Cash figures came in at -$57.5 million (Q1 2026), $405.9 million (Q4 2025), and -$12.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 2.44 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 417.10 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn -153.10 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 53.61 Mn
10 Wave Life Sciences 1.32 Bn 772.50 Mn - -57.47 Mn

Historic Data

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DateValue
Mar 31, 2026 -57.47 Mn
Dec 31, 2025 405.86 Mn
Sep 30, 2025 -12.25 Mn
Jun 30, 2025 -34.58 Mn
Mar 31, 2025 -58.99 Mn
Dec 31, 2024 -8.86 Mn
Sep 30, 2024 157.01 Mn
Jun 30, 2024 -26.95 Mn
Mar 31, 2024 -19.41 Mn
Dec 31, 2023 60.43 Mn
Sep 30, 2023 -33.02 Mn
Jun 30, 2023 -35.58 Mn
Mar 31, 2023 120.07 Mn
Dec 31, 2022 -8.45 Mn
Sep 30, 2022 -26.21 Mn
Jun 30, 2022 61.45 Mn
Mar 31, 2022 -88.85 Mn
Dec 31, 2021 26.67 Mn
Sep 30, 2021 -19.94 Mn
Jun 30, 2021 -4.70 Mn
Mar 31, 2021 -35.96 Mn
Dec 31, 2020 -31.87 Mn
Sep 30, 2020 122.31 Mn
Jun 30, 2020 -26.89 Mn
Mar 31, 2020 -26.21 Mn
Dec 31, 2019 -61.84 Mn
Sep 30, 2019 -43.89 Mn
Jun 30, 2019 -34.66 Mn
Mar 31, 2019 112.75 Mn
Dec 31, 2018 -35.67 Mn
Sep 30, 2018 -30.94 Mn
Jun 30, 2018 130.94 Mn
Mar 31, 2018 -32.01 Mn
Dec 31, 2017 -25.96 Mn
Sep 30, 2017 -28.93 Mn
Jun 30, 2017 67.91 Mn
Mar 31, 2017 -20.81 Mn
Dec 31, 2016 -16.18 Mn
Sep 30, 2016 -12.75 Mn
Jun 30, 2016 28.37 Mn
Mar 31, 2016 -7.82 Mn
Dec 31, 2015 95.18 Mn
Sep 30, 2015 58.26 Mn
Jun 30, 2015 -3.18 Mn
Mar 31, 2015 9.91 Mn
Dec 31, 2014 -1.44 Mn