VYNE Therapeutics (VYNE) Return on Sales (2017 - 2026)

VYNE Therapeutics (VYNE) posted Return on Sales of 0.0% for Q1 2026, up 57.36% on a QoQ basis from 0.0% in Q2 2025, and little changed year-over-year from 0.0% in Q1 2025.

VYNE Therapeutics (VYNE) Return on Sales (2017 - 2026) Analysis & Trends

VYNE Therapeutics' Return on Sales history runs 10 years deep, the most recent figure standing at 0.0% for Q1 2026.

  • Quarterly Return on Sales changed 0.0% year-over-year to 0.0% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.0% (changed 0.0% YoY) and the FY2025 annual result came in at 0.0%, changed 0.0% from the prior year.
  • Return on Sales was 0.0% for Q1 2026 at VYNE Therapeutics, up from 0.0% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.75% in Q1 2022 and bottomed at 0.75% in Q4 2022.
  • A 5-year average of 0.01% and a median of 0.0% in 2023 frame the typical range for Return on Sales.
  • Annual changes were most pronounced in 2022 — Return on Sales soared 117 bps — and 2023, when it plunged 75 bps.
  • VYNE Therapeutics' Return on Sales stood at 0.75% in 2022, then soared by 99 bps to 0.0% in 2023, then jumped by 80 bps to 0.0% in 2024, then rose by 17 bps to 0.0% in 2025, then jumped by 57 bps to 0.0% in 2026.
  • Business Quant data shows VYNE's Return on Sales at 0.0% in Q1 2026, 0.0% in Q2 2025, and 0.0% in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 0.00%
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 0.00%
7 Belite Bio 62.72 Bn 62.72 Bn - -
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.35 Bn 37.35 Bn - -
10 VYNE Therapeutics 1.19 Bn 1.16 Bn - 0.00%

Historic Data

Download Data
DateValue
Mar 31, 2026 0.00%
Jun 30, 2025 0.00%
Mar 31, 2025 0.00%
Dec 31, 2024 0.00%
Sep 30, 2024 0.00%
Jun 30, 2024 0.00%
Mar 31, 2024 0.00%
Dec 31, 2023 0.00%
Sep 30, 2023 -0.05%
Jun 30, 2023 0.00%
Mar 31, 2023 0.00%
Dec 31, 2022 -0.75%
Sep 30, 2022 -0.01%
Jun 30, 2022 -0.02%
Mar 31, 2022 0.75%
Dec 31, 2021 -0.12%
Sep 30, 2021 -0.53%
Jun 30, 2021 -0.31%
Mar 31, 2021 -0.42%
Dec 31, 2020 -0.05%