Growth Metrics

VYNE Therapeutics (VYNE) Return on Sales (2017 - 2025)

VYNE Therapeutics (VYNE) has disclosed Return on Sales for 9 consecutive years, with 0.06% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Return on Sales rose 3.0% year-over-year to 0.06%, compared with a TTM value of 0.06% through Dec 2025, down 1.0%, and an annual FY2025 reading of 0.44%, up 50.0% over the prior year.
  • Return on Sales was 0.06% for Q4 2025 at VYNE Therapeutics, up from 0.08% in the prior quarter.
  • Across five years, Return on Sales topped out at 75.08% in Q1 2022 and bottomed at 74.66% in Q4 2022.
  • Average Return on Sales over 5 years is 7.7%, with a median of 0.15% recorded in 2023.
  • The sharpest move saw Return on Sales soared 11714bps in 2022, then crashed -7518bps in 2023.
  • Year by year, Return on Sales stood at 11.71% in 2021, then plummeted by -537bps to 74.66% in 2022, then skyrocketed by 99bps to 0.49% in 2023, then skyrocketed by 80bps to 0.1% in 2024, then soared by 34bps to 0.06% in 2025.
  • Business Quant data shows Return on Sales for VYNE at 0.06% in Q4 2025, 0.08% in Q2 2025, and 0.04% in Q1 2025.