VYNE Therapeutics's three largest insider shareholders as of April 22, 2026 are Advisors Llc Perceptive (TenPercentOwner, 4.94Mn shares), Advisors Llc Perceptive (TenPercentOwner, 4.94Mn shares), David Domzalski (President And Ceo, 401.98K shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Advisors Llc Perceptive | - | 0 | 4,935,057 | 18 Aug, 2021 |
| Advisors Llc Perceptive | - | 0 | 4,935,057 | 18 Aug, 2021 |
| David Domzalski | President And Ceo | 401,976 | 0 | 02 Apr, 2026 |
| Mutya Harsch | Chief Legal Officer And Gc | 121,898 | 0 | 02 Apr, 2026 |
| Iain Stuart | Chief Scientific Officer | 112,363 | 0 | 02 Apr, 2026 |
| Matthew T. Wiley | Chief Commercial Officer | 109,246 | 0 | 02 Jul, 2021 |
| Tyler Zeronda | Chief Financial Officer | 99,788 | 0 | 02 Apr, 2026 |
| Patrick G Lepore | - | 51,472 | 0 | 16 Jan, 2025 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 31 Mar, 2026 | Tyler Zeronda | Common Stock | D | 4,007 | $0.60 | 99,788 | D | F |
| 31 Mar, 2026 | Mutya Harsch | Common Stock | D | 4,007 | $0.60 | 121,898 | D | F |
| 31 Mar, 2026 | Iain Stuart | Common Stock | D | 2,876 | $0.60 | 112,363 | D | F |
| 31 Mar, 2026 | David Domzalski | Common Stock | D | 14,232 | $0.60 | 401,976 | D | F |
| 31 Dec, 2025 | David Domzalski | Common Stock | D | 12,684 | $0.58 | 416,208 | D | F |
| 31 Dec, 2025 | Iain Stuart | Common Stock | D | 2,448 | $0.58 | 115,239 | D | F |
| 31 Dec, 2025 | Mutya Harsch | Common Stock | D | 3,579 | $0.58 | 125,905 | D | F |
| 31 Dec, 2025 | Tyler Zeronda | Common Stock | D | 7,858 | $0.58 | 103,795 | D | F |
| 12 Dec, 2025 | Patrick G Lepore | Stock Option (right to buy) | A | 20,000 | $0.00 | 20,000 | D | A |
| 12 Dec, 2025 | Sharon Barbari | Stock Option (right to buy) | A | 20,000 | $0.00 | 20,000 | D | A |
| 12 Dec, 2025 | Elisabeth Sandoval Little | Stock Option (right to buy) | A | 20,000 | $0.00 | 20,000 | D | A |
| 12 Dec, 2025 | Steven L Basta | Stock Option (right to buy) | A | 20,000 | $0.00 | 20,000 | D | A |
| 30 Sep, 2025 | Mutya Harsch | Common Stock | D | 3,581 | $0.34 | 129,484 | D | F |
| 30 Sep, 2025 | Iain Stuart | Common Stock | D | 2,453 | $0.34 | 117,687 | D | F |
| 30 Sep, 2025 | David Domzalski | Common Stock | D | 12,676 | $0.34 | 428,892 | D | F |
| 30 Sep, 2025 | Tyler Zeronda | Common Stock | D | 3,420 | $0.34 | 111,653 | D | F |
| 30 Jun, 2025 | Mutya Harsch | Common Stock | D | 3,581 | $1.65 | 133,065 | D | F |
| 30 Jun, 2025 | Iain Stuart | Common Stock | D | 2,453 | $1.65 | 120,140 | D | F |
| 30 Jun, 2025 | David Domzalski | Common Stock | D | 12,676 | $1.65 | 441,568 | D | F |
| 30 Jun, 2025 | Tyler Zeronda | Common Stock | D | 3,420 | $1.65 | 115,073 | D | F |