VYNE Therapeutics Inc. (VYNE) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

1,173,933Shares held by institutions

$681,468Value of institutional holdings

16.91%Institutional ownership %

30.85%Shares Changed QoQ

45No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

VYNE Therapeutics Inc. (NASDAQ:VYNE) has 44 institutional investors that have filed 13F reports for the period ending December 2025.

Their combined ownership stood at 19.8% of outstanding shares in December 2025, up from 9.3% in September 2025.
They increased total shares held in VYNE Therapeutics by 182.88% from last quarter, and the number of investors in VYNE increased 22.22% annually.
Activity in VYNE broke down as 22 buyers, 9 sellers, and 13 unchanged among 44 total holders.
Combined, these investors held 8.49Mn shares in VYNE for December 2025, up by 5.49Mn shares quarter on quarter, and up 855.98K shares year over year.
Shay Capital LLC leads ownership in VYNE with 1.62Mn shares as of December 31, 2025, equal to 3.8% of outstanding shares.
Leading buyers of VYNE Therapeutics shares for the quarter ending December 2025 were Anson Funds Management LP (1.27Mn), Shay Capital LLC (1.13Mn), Nantahala Capital Management, LLC (1.0Mn), T3 Companies, LLC (945.0K), ADAR1 Capital Management, LLC (507.58K).
Leading sellers of VYNE Therapeutics shares for the quarter ending December 2025 were ACORN CAPITAL ADVISORS, LLC (585.15K), JANE STREET GROUP, LLC (74.76K), BOOTHBAY FUND MANAGEMENT, LLC (25.09K), Ikarian Capital, LLC (25.09K), Bank Of America Corp /De/ (1.39K).
VYNE Therapeutics's 10 largest shareholders as of December 2025 include Shay Capital LLC (1.62Mn), Anson Funds Management LP (1.27Mn), Nantahala Capital Management, LLC (1.0Mn), T3 Companies, LLC (945.0K), ACADIAN ASSET MANAGEMENT LLC (638.49K), ADAR1 Capital Management, LLC (507.58K), KVP Capital Advisors, LP (500.55K), VANGUARD GROUP INC (314.54K), Ikarian Capital, LLC (264.91K), GEODE CAPITAL MANAGEMENT, LLC (225.15K) per Business Quant data.

44 Institutional Holders

1,173,933 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	0	0.00%	$0.00
Anson Funds Management LP	31 Dec, 2025	1,274,386	0.00%	$0.00
Shay Capital LLC	31 Dec, 2025	1,131,772	229.77%	$0.00
Nantahala Capital Management, LLC	31 Dec, 2025	1,000,000	0.00%	$0.00
T3 Companies, LLC	31 Dec, 2025	945,000	0.00%	$0.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	192,078	43.03%	$0.00
ADAR1 Capital Management, LLC	31 Dec, 2025	507,582	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	124,162	65.22%	$0.00
KVP Capital Advisors, LP	31 Dec, 2025	500,551	0.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	88,030	64.20%	$0.00
Ikarian Capital, LLC	31 Dec, 2025	-25,088	-8.65%	$0.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	-788	-0.36%	$0.00
XTX Topco Ltd	31 Dec, 2025	79,040	0.00%	$0.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	106,500	188.16%	$0.00
UBS Group AG	31 Dec, 2025	57,189	1,026.36%	$0.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	42,578	73.71%	$0.00
FNY Investment Advisers, LLC	31 Dec, 2025	25,000	0.00%	$0.00
Rangeley Capital, LLC	31 Dec, 2025	50,000	100.00%	$0.00
ACORN CAPITAL ADVISORS, LLC	31 Dec, 2025	-585,147	-99.76%	$0.00
BOOTHBAY FUND MANAGEMENT, LLC	31 Dec, 2025	-25,088	-23.57%	$0.00

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