VYNE Therapeutics (VYNE) Operating Expenses (2016 - 2026)

VYNE Therapeutics (VYNE) posted Operating Expenses of $3.9 million for Q1 2026, down 48.73% on a QoQ basis from $7.6 million in Q2 2025, and down 58.48% year-over-year from $9.4 million in Q1 2025.

VYNE Therapeutics (VYNE) Operating Expenses (2016 - 2026) Analysis & Trends

VYNE Therapeutics' Operating Expenses history runs 11 years deep, the most recent figure standing at $3.9 million for Q1 2026.

  • Quarterly Operating Expenses fell 58.48% year-over-year to $3.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $20.9 million (down 54.6% YoY) and the FY2025 annual result came in at $30.3 million, down 31.31% from the prior year.
  • Operating Expenses was $3.9 million for Q1 2026 at VYNE Therapeutics, down from $7.6 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $13.2 million in Q3 2024 and bottomed at $3.9 million in Q1 2026.
  • A 5-year average of $8.6 million and a median of $8.4 million in 2022 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2024 — Operating Expenses soared 108.13% — and 2026, when it sank 58.48%.
  • VYNE Therapeutics' Operating Expenses stood at $8.0 million in 2022, then fell by 13.54% to $6.9 million in 2023, then jumped by 86.07% to $12.9 million in 2024, then plunged by 40.79% to $7.6 million in 2025, then sank by 48.73% to $3.9 million in 2026.
  • Business Quant data shows VYNE's Operating Expenses at $3.9 million in Q1 2026, $7.6 million in Q2 2025, and $9.4 million in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 66,621.14 Bn 66,620.85 Bn - -28.01 Mn
2 Nanobiotix 1,915.18 Bn 1,915.11 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.27 Bn 466.48 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.81 Bn 114.57 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 69.58 Bn 60.82 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.72 Bn 62.72 Bn - 32.68 Mn
8 Argenx Se 55.51 Bn 50.33 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.35 Bn 37.35 Bn - 445.22 Mn
10 VYNE Therapeutics 1.19 Bn 1.16 Bn - 3.90 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 3.90 Mn
Jun 30, 2025 7.61 Mn
Mar 31, 2025 9.40 Mn
Dec 31, 2024 12.85 Mn
Sep 30, 2024 13.21 Mn
Jun 30, 2024 10.59 Mn
Mar 31, 2024 7.48 Mn
Dec 31, 2023 6.91 Mn
Sep 30, 2023 6.35 Mn
Jun 30, 2023 10.45 Mn
Mar 31, 2023 5.97 Mn
Dec 31, 2022 7.99 Mn
Sep 30, 2022 9.50 Mn
Jun 30, 2022 8.41 Mn
Mar 31, 2022 8.87 Mn
Dec 31, 2021 9.12 Mn
Sep 30, 2021 10.90 Mn
Jun 30, 2021 9.84 Mn
Mar 31, 2021 9.99 Mn
Dec 31, 2020 25.74 Mn