Vertex Pharmaceuticals Inc / Ma (VRTX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

258,000,000Shares Outstanding

235,260,470Shares held by institutions

$102,444,171,662Value of institutional holdings

91.19%Institutional ownership %

-0.46%Shares Changed QoQ

1,616No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Vertex Pharmaceuticals Inc / Ma (NASDAQ:VRTX) is held by 1,611 institutional investors per 13F filings through December 2025.

These investors collectively held 90.2% of Vertex Pharmaceuticals's outstanding shares in December 2025, down from 93.8% in September 2025.
They decreased total shares held in VRTX by -0.81% quarter over quarter, and investors in Vertex Pharmaceuticals increased 6.06% from a year ago.
During the quarter, 855 of these 1,611 funds increased positions in VRTX, 552 reduced exposure, and 204 held steady.
Combined, these investors held 232.73Mn shares in VRTX for December 2025, down by 1.91Mn shares quarter on quarter, and down 13.54Mn shares year over year.
As of December 31, 2025, the biggest holder of Vertex Pharmaceuticals is LVM CAPITAL MANAGEMENT LTD/MI at 25.83K shares, representing 0.01% of shares outstanding.
The biggest buyers of Vertex Pharmaceuticals for the quarter ending December 2025 included Ares Financial Consulting, LLC (167), LVM CAPITAL MANAGEMENT LTD/MI (55), Hickory Point Bank & Trust (4).
The largest sales of VRTX for the quarter ending December 2025 came from Signature Wealth Management Group (3.8K), Bangor Savings Bank (126), Coastline Trust Co (60), ADIRONDACK TRUST CO (24).
Per Business Quant, the top 10 investors in VRTX for the quarter ending December 2025 include LVM CAPITAL MANAGEMENT LTD/MI (25.83K), Bangor Savings Bank (4.45K), Coastline Trust Co (537), Signature Wealth Management Group (527), ADIRONDACK TRUST CO (459), Hilltop National Bank (272), Ares Financial Consulting, LLC (240), Sankala Group LLC (233), Aspect Partners, LLC (21), Hickory Point Bank & Trust (4).

1,616 Institutional Holders

235,260,470 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Capital World Investors	31 Dec, 2025	25,510,182	-400,405	-1.55%	$11,565,309,006.00
VANGUARD GROUP INC	31 Dec, 2025	24,105,823	-111,042	-0.46%	$10,928,615,915.00
BlackRock, Inc.	31 Dec, 2025	23,751,989	1,498,942	6.74%	$10,768,201,653.00
Capital Research Global Investors	31 Dec, 2025	17,316,344	763,063	4.61%	$7,850,543,946.00
State Street Corp	31 Dec, 2025	11,689,539	83,539	0.72%	$5,299,569,401.00
Jpmorgan Chase & Co	31 Dec, 2025	6,039,481	-6,830,075	-53.07%	$2,738,059,237.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	5,981,905	8,160	0.14%	$2,700,207,827.00
Capital International Investors	31 Dec, 2025	4,733,596	44,537	0.95%	$2,146,040,530.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	4,496,482	-26,104	-0.58%	$2,038,525,080.00
LOOMIS SAYLES & CO L P	31 Dec, 2025	4,033,525	-88,603	-2.15%	$1,828,638,685.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,821,731	-950,311	-19.91%	$1,732,619,966.00
Goldman Sachs Group Inc	31 Dec, 2025	3,507,520	2,022,862	136.25%	$1,590,169,538.00
VICTORY CAPITAL MANAGEMENT INC	31 Dec, 2025	3,356,766	1,109,200	49.35%	$1,521,850,963.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	3,249,541	-205,406	-5.95%	$1,473,211,801.00
NORGES BANK	31 Dec, 2025	3,176,613	3,176,613	0.00%	$1,440,149,270.00
Morgan Stanley	31 Dec, 2025	3,120,310	11,905	0.38%	$1,414,625,263.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	3,000,778	113,661	3.94%	$1,360,432,714.00
Bank Of America Corp /De/	31 Dec, 2025	2,937,030	-2,743,818	-48.30%	$1,331,532,113.00
Clearbridge Investments, LLC	31 Dec, 2025	2,860,176	214,412	8.10%	$1,296,689,269.00
Northern Trust Corp	31 Dec, 2025	2,579,457	-48,430	-1.84%	$1,169,422,624.00

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