Vertex Pharmaceuticals Inc / Ma (VRTX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

396,459Shares held by institutions

$175,670,983Value of institutional holdings

93.79%Institutional ownership %

-0.26%Shares Changed QoQ

1,537No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Vertex Pharmaceuticals Inc / Ma (NASDAQ:VRTX) has 1,611 institutional investors with active 13F positions as of December 2025.

These investors collectively held 90.2% of Vertex Pharmaceuticals's outstanding shares in December 2025, down from 93.8% in September 2025.
They decreased total shares held in Vertex Pharmaceuticals by -0.81% from last quarter, and the number of investors in VRTX increased 6.06% annually.
Among the 1,611 funds, 855 bought more Vertex Pharmaceuticals shares, 552 sold down, and 204 held their ground.
The aggregate institutional position in Vertex Pharmaceuticals amounted to 232.73Mn shares as of December 2025, down by 1.91Mn shares quarter on quarter, and down 13.54Mn shares year over year.
Capital World Investors leads ownership in VRTX with 25.51Mn shares as of December 31, 2025, equal to 9.89% of outstanding shares.
Leading buyers of Vertex Pharmaceuticals shares for the quarter ending December 2025 were NORGES BANK (3.18Mn), BlackRock, Inc. (1.5Mn), VICTORY CAPITAL MANAGEMENT INC (1.11Mn), Winslow Capital Management, LLC (887.64K), Capital Research Global Investors (763.06K).
The largest sales of VRTX for the quarter ending December 2025 came from Jpmorgan Chase & Co (6.83Mn), Bank Of America Corp /De/ (2.74Mn), FMR LLC (1.09Mn), WELLINGTON MANAGEMENT GROUP LLP (950.31K), DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main (537.7K).
Business Quant data shows the 10 biggest positions in Vertex Pharmaceuticals as of December 2025 are held by Capital World Investors (25.51Mn), VANGUARD GROUP INC (24.11Mn), BlackRock, Inc. (23.75Mn), Capital Research Global Investors (17.32Mn), State Street Corp (11.69Mn), Jpmorgan Chase & Co (6.04Mn), GEODE CAPITAL MANAGEMENT, LLC (5.98Mn), Capital International Investors (4.73Mn), ALLIANCEBERNSTEIN L.P. (4.5Mn), LOOMIS SAYLES & CO L P (4.03Mn).

1,614 Institutional Holders

396,459 Total Shares Held

Rows:

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Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	1,498,942	6.74%	$0.00
Capital World Investors	31 Dec, 2025	-400,405	-1.55%	$0.00
Nuveen, LLC	31 Dec, 2025	-35,313	-3.28%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	623,246	97.79%	$0.00
Larry Mathis Financial Planning, LLC	31 Dec, 2025	1,693	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	-111,042	-0.46%	$0.00
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main	31 Dec, 2025	-537,697	-40.08%	$0.00
Barclays Plc	31 Dec, 2025	-834,065	-49.59%	$0.00
Capital Research Global Investors	31 Dec, 2025	763,063	4.61%	$0.00
Pictet Asset Management Holding SA	31 Dec, 2025	-39,033	-4.93%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	178,999	192.86%	$0.00
State Street Corp	31 Dec, 2025	83,539	0.72%	$0.00
Bellevue Group AG	31 Dec, 2025	175,315	34.66%	$0.00
World Investment Advisors	31 Dec, 2025	2,513	175.61%	$0.00
Jpmorgan Chase & Co	31 Dec, 2025	-6,830,075	-53.07%	$0.00
UBS Group AG	31 Dec, 2025	-217,066	-28.08%	$0.00
Purpose Unlimited Inc.	31 Dec, 2025	835	0.00%	$0.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	8,160	0.14%	$0.00
National Pension Service	31 Dec, 2025	18,728	3.66%	$0.00
PEAK6 LLC	31 Dec, 2025	-23,872	-97.77%	$0.00

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