Vertex Pharmaceuticals Inc / Ma (VRTX) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

258,000,000Shares Outstanding

235,289,469Shares held by institutions

$100,868,595,360Value of institutional holdings

91.20%Institutional ownership %

-0.46%Shares Changed QoQ

1,619No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Vertex Pharmaceuticals Inc / Ma (NASDAQ:VRTX) has 1,611 institutional investors that have filed 13F reports for the period ending December 2025.

Their combined ownership stood at 90.2% of outstanding shares in December 2025, down from 93.8% in September 2025.
Their total shares held in VRTX decreased -0.81% quarter over quarter, and separately, investors owning Vertex Pharmaceuticals increased 6.06% from a year ago.
Of these 1,611 holders, 855 added to their stakes in Vertex Pharmaceuticals, 552 trimmed positions, and 204 made no changes.
In total, institutional investors held 232.73Mn shares in Vertex Pharmaceuticals as of December 2025, down by 1.91Mn shares quarter on quarter, and down 13.54Mn shares year over year.
Assenagon Asset Management S.A. leads ownership in VRTX with 537.25K shares as of December 31, 2025, equal to 0.21% of outstanding shares.
Leading buyers of Vertex Pharmaceuticals shares for the quarter ending December 2025 were WEALTH ENHANCEMENT ADVISORY SERVICES, LLC (40.67K), BI Asset Management Fondsmaeglerselskab A/S (39.01K), OP Asset Management Ltd (23.93K), STRATEGIC PLANNING GROUP, LLC (17.39K), Janney Montgomery Scott LLC (13.97K).
Top sellers of VRTX stock for the quarter ending December 2025 included Pictet Asset Management Holding SA (414.86K), Assenagon Asset Management S.A. (295.6K), BEACON INVESTMENT ADVISORY SERVICES, INC. (92.08K), SG Americas Securities, LLC (58.92K), ABN AMRO Bank N.V. (36.87K).
Per Business Quant, the top 10 investors in VRTX for the quarter ending December 2025 include Assenagon Asset Management S.A. (537.25K), Robeco Institutional Asset Management B.V. (401.64K), Pictet Asset Management Holding SA (337.57K), DAVENPORT & Co LLC (210.15K), ABN AMRO Bank N.V. (118.35K), COUNTRY TRUST BANK (105.08K), Raiffeisen Bank International AG (101.44K), Janney Montgomery Scott LLC (84.32K), Lansforsakringar Fondforvaltning AB (publ) (83.85K), STRS OHIO (74.16K).

1,631 Institutional Holders

235,289,469 Total Shares Held

Rows:

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Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Capital World Investors	31 Dec, 2025	25,510,182	-400,405	-1.55%	$11,565,309,006.00
VANGUARD GROUP INC	31 Dec, 2025	24,105,823	-111,042	-0.46%	$10,928,615,915.00
BlackRock, Inc.	31 Dec, 2025	23,751,989	1,498,942	6.74%	$10,768,201,653.00
Capital Research Global Investors	31 Dec, 2025	17,316,344	763,063	4.61%	$7,850,543,946.00
State Street Corp	31 Dec, 2025	11,689,539	83,539	0.72%	$5,299,569,401.00
Jpmorgan Chase & Co	31 Dec, 2025	6,039,481	-6,830,075	-53.07%	$2,738,059,237.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	5,981,905	8,160	0.14%	$2,700,207,827.00
Capital International Investors	31 Dec, 2025	4,733,596	44,537	0.95%	$2,146,040,530.00
ALLIANCEBERNSTEIN L.P.	31 Dec, 2025	4,496,482	-26,104	-0.58%	$2,038,525,080.00
LOOMIS SAYLES & CO L P	31 Dec, 2025	4,033,525	-88,603	-2.15%	$1,828,638,685.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,821,731	-950,311	-19.91%	$1,732,619,966.00
Goldman Sachs Group Inc	31 Dec, 2025	3,507,520	2,022,862	136.25%	$1,590,169,538.00
VICTORY CAPITAL MANAGEMENT INC	31 Dec, 2025	3,356,766	1,109,200	49.35%	$1,521,850,963.00
JENNISON ASSOCIATES LLC	31 Dec, 2025	3,249,541	-205,406	-5.95%	$1,473,211,801.00
NORGES BANK	31 Dec, 2025	3,176,613	3,176,613	0.00%	$1,440,149,270.00
Morgan Stanley	31 Dec, 2025	3,120,310	11,905	0.38%	$1,414,625,263.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	3,000,778	113,661	3.94%	$1,360,432,714.00
Bank Of America Corp /De/	31 Dec, 2025	2,937,030	-2,743,818	-48.30%	$1,331,532,113.00
Clearbridge Investments, LLC	31 Dec, 2025	2,860,176	214,412	8.10%	$1,296,689,269.00
Northern Trust Corp	31 Dec, 2025	2,579,457	-48,430	-1.84%	$1,169,422,624.00

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