Growth Metrics

Vanda Pharmaceuticals (VNDA) Operating Income (2010 - 2026)

Vanda Pharmaceuticals recorded quarterly Operating Income of -$50.2 million in Q1 2026, down 24.46% quarter-over-quarter from -$40.4 million in Q4 2025, and down 22.41% year-over-year from -$64.7 million in Q1 2025.

Vanda Pharmaceuticals' Operating Income history runs 17 years deep, the most recent figure standing at -$50.2 million for Q1 2026.

  • In Q1 2026, Operating Income fell 22.41% year-over-year to -$50.2 million; the TTM figure through Mar 2026 stood at -$160.4 million (down 121.34% YoY), while the FY2025 annual figure was -$151.2 million, down 271.79% from the prior year.
  • Operating Income came in at -$50.2 million for Q1 2026 at Vanda Pharmaceuticals, down from -$40.4 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $6.6 million in Q4 2022 to a low of -$50.2 million in Q1 2026.
  • A 5-year average of -$14.7 million and a median of -$9.2 million in 2024 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income surged 126.13% in 2023 and slumped 560.83% in 2024, its largest moves.
  • Vanda Pharmaceuticals' Operating Income stood at $6.6 million in 2022, then slumped by 207.01% to -$7.1 million in 2023, then tumbled by 44.9% to -$10.3 million in 2024, then tumbled by 292.58% to -$40.4 million in 2025, then slipped by 24.46% to -$50.2 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$50.2 million, -$40.4 million, and -$31.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Vanda Pharmaceuticals 379.35 Mn 177.04 Mn 48.56 Mn -50.22 Mn

Historic Data

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DateValue
Mar 31, 2026 -50.22 Mn
Dec 31, 2025 -40.35 Mn
Sep 30, 2025 -31.28 Mn
Jun 30, 2025 -38.50 Mn
Mar 31, 2025 -41.03 Mn
Dec 31, 2024 -10.28 Mn
Sep 30, 2024 -11.00 Mn
Jun 30, 2024 -10.15 Mn
Mar 31, 2024 -9.24 Mn
Dec 31, 2023 -7.09 Mn
Sep 30, 2023 -6.00 Mn
Jun 30, 2023 -2.87 Mn
Mar 31, 2023 2.00 Mn
Dec 31, 2022 6.63 Mn
Sep 30, 2022 3.91 Mn
Jun 30, 2022 3.46 Mn
Mar 31, 2022 -7.67 Mn
Dec 31, 2021 8.64 Mn
Sep 30, 2021 10.82 Mn
Jun 30, 2021 12.37 Mn
Mar 31, 2021 10.34 Mn
Dec 31, 2020 10.45 Mn
Sep 30, 2020 7.74 Mn
Jun 30, 2020 9.17 Mn
Mar 31, 2020 -125,000.00
Dec 31, 2019 4.24 Mn
Sep 30, 2019 10.76 Mn
Jun 30, 2019 9.90 Mn
Mar 31, 2019 -2.09 Mn
Dec 31, 2018 9.15 Mn
Sep 30, 2018 6.23 Mn
Jun 30, 2018 3.91 Mn
Mar 31, 2018 2.44 Mn
Dec 31, 2017 -2.15 Mn
Sep 30, 2017 -4.92 Mn
Jun 30, 2017 -1.92 Mn
Mar 31, 2017 -7.91 Mn
Dec 31, 2016 -654,000.00
Sep 30, 2016 -653,000.00
Jun 30, 2016 -4.79 Mn
Mar 31, 2016 -12.48 Mn
Dec 31, 2015 -14.89 Mn
Sep 30, 2015 -9.54 Mn
Jun 30, 2015 -5.46 Mn
Mar 31, 2015 -10.29 Mn
Dec 31, 2014 69.69 Mn
Sep 30, 2014 -1.45 Mn
Jun 30, 2014 -21.61 Mn
Mar 31, 2014 -26.58 Mn
Dec 31, 2013 -7.79 Mn
Sep 30, 2013 -5.43 Mn
Jun 30, 2013 -3.41 Mn
Mar 31, 2013 -4.57 Mn
Dec 31, 2012 -6.43 Mn
Sep 30, 2012 -5.40 Mn
Jun 30, 2012 -8.09 Mn
Mar 31, 2012 -8.32 Mn
Dec 31, 2011 -5.91 Mn
Sep 30, 2011 -3.29 Mn
Jun 30, 2011 -1.51 Mn
Mar 31, 2011 7,000.00
Dec 31, 2010 791,000.00
Sep 30, 2010 743,000.00
Jun 30, 2010 1.16 Mn