Vanda Pharmaceuticals (VNDA) Net Margin (2010 - 2026)
Vanda Pharmaceuticals' Net Margin was -123.72% in Q2 2026, down 71.98 percentage points from -51.73% a year earlier and down 29.81 percentage points from the prior quarter.
Powered by 
Analysis
Vanda Pharmaceuticals (VNDA) Net Margin (2010 - 2026) Analysis & Trends
On a trailing twelve-month basis, Vanda Pharmaceuticals' Net Margin was -127.41% through Jun 30, 2026, down 94.51 percentage points year-over-year; for FY2025, it was -102.02%, down 92.51 percentage points from FY2024.
- Net Margin has now declined for four consecutive years, with a five-year change of -111.43 percentage points (FY2020 to FY2025).
- In earlier years, Net Margin was -9.51% in FY2024 (-10.81 pp), 1.30% in FY2023 (-1.16 pp), 2.47% in FY2022 (-9.87 pp) and 12.34% in FY2021 (+2.94 pp).
- Quarterly Net Margin has moved between -246.76% (Q4 2025) and 11.09% (Q3 2021) over five years.
- Compared with a year earlier, Net Margin has declined for 13 straight quarters, with an average year-over-year change of -60.24 percentage points over the last eight quarters.
- The best year-over-year quarter for Net Margin over five years was Q1 2023 (a gain of 15.89 percentage points); the worst was Q4 2025 (a drop of 237.53 percentage points).
- Per Business Quant data, VNDA's Net Margin in the three quarters before Q2 2026 was -93.91% (Q1 2026), -246.76% (Q4 2025) and -40.15% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Vanda Pharmaceuticals | 312.55 Mn | -617.39 Mn | 46.97 Mn | -123.72% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -123.72% |
| Mar 31, 2026 | -93.91% |
| Dec 31, 2025 | -246.76% |
| Sep 30, 2025 | -40.15% |
| Jun 30, 2025 | -51.73% |
| Mar 31, 2025 | -58.94% |
| Dec 31, 2024 | -9.24% |
| Sep 30, 2024 | -11.17% |
| Jun 30, 2024 | -8.95% |
| Mar 31, 2024 | -8.74% |
| Dec 31, 2023 | -5.30% |
| Sep 30, 2023 | 0.35% |
| Jun 30, 2023 | 3.30% |
| Mar 31, 2023 | 5.20% |
| Dec 31, 2022 | 10.64% |
| Sep 30, 2022 | 5.01% |
| Jun 30, 2022 | 4.00% |
| Mar 31, 2022 | -10.68% |
| Dec 31, 2021 | 10.41% |
| Sep 30, 2021 | 11.09% |
API Access
Vanda Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "VNDA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();