Growth Metrics

Vanda Pharmaceuticals (VNDA) Net Margin (2010 - 2026)

Vanda Pharmaceuticals recorded quarterly Net Margin of 93.82% in Q1 2026, up 61.99% quarter-over-quarter from 246.83% in Q4 2025, and down 3488.0% year-over-year from 2.77% in Q1 2025.

Vanda Pharmaceuticals' Net Margin history runs 17 years deep, the most recent figure standing at 93.82% for Q1 2026.

  • In Q1 2026, Net Margin fell 3488.0% year-over-year to 93.82%; the TTM figure through Mar 2026 stood at 109.99% (down 8802.0% YoY), while the FY2025 annual figure was 102.02%, down 9251.0% from the prior year.
  • Net Margin came in at 93.82% for Q1 2026 at Vanda Pharmaceuticals, up from 246.83% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 10.64% in Q4 2022 to a low of 246.83% in Q4 2025.
  • A 5-year average of 30.42% and a median of 8.95% in 2024 frame the typical range for Net Margin.
  • Across the five-year window, Net Margin soared 1585 bps in 2023 and slumped 23767 bps in 2025, its largest moves.
  • Vanda Pharmaceuticals' Net Margin stood at 10.64% in 2022, then slumped by 150 bps to 5.28% in 2023, then tumbled by 74 bps to 9.17% in 2024, then slumped by 2592 bps to 246.83% in 2025, then surged by 62 bps to 93.82% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 93.82%, 246.83%, and 40.15% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.82%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 34.53%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 20.17%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.65%
10 Vanda Pharmaceuticals 379.35 Mn 177.04 Mn 48.56 Mn -93.82%

Historic Data

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DateValue
Mar 31, 2026 -93.82%
Dec 31, 2025 -246.83%
Sep 30, 2025 -40.15%
Jun 30, 2025 -51.70%
Mar 31, 2025 -58.94%
Dec 31, 2024 -9.17%
Sep 30, 2024 -11.21%
Jun 30, 2024 -8.95%
Mar 31, 2024 -8.77%
Dec 31, 2023 -5.28%
Sep 30, 2023 0.35%
Jun 30, 2023 3.24%
Mar 31, 2023 5.16%
Dec 31, 2022 10.64%
Sep 30, 2022 4.99%
Jun 30, 2022 4.02%
Mar 31, 2022 -10.68%
Dec 31, 2021 10.41%
Sep 30, 2021 11.09%
Jun 30, 2021 14.22%
Mar 31, 2021 13.80%
Dec 31, 2020 12.13%
Sep 30, 2020 9.86%
Jun 30, 2020 13.97%
Mar 31, 2020 0.84%
Dec 31, 2019 6.95%
Sep 30, 2019 168.82%
Jun 30, 2019 19.52%
Mar 31, 2019 -1.28%
Dec 31, 2018 19.57%
Sep 30, 2018 14.58%
Jun 30, 2018 9.74%
Mar 31, 2018 7.03%
Dec 31, 2017 -4.15%
Sep 30, 2017 -11.01%
Jun 30, 2017 -3.65%
Mar 31, 2017 -20.43%
Dec 31, 2016 -1.31%
Sep 30, 2016 -1.12%
Jun 30, 2016 -12.82%
Mar 31, 2016 -37.15%
Dec 31, 2015 -46.76%
Sep 30, 2015 -33.66%
Jun 30, 2015 -19.79%
Mar 31, 2015 -46.47%
Dec 31, 2014 453.44%
Sep 30, 2014 -9.80%
Jun 30, 2014 -198.63%
Mar 31, 2014 -290.20%
Dec 31, 2013 -86.79%
Sep 30, 2013 -61.78%
Jun 30, 2013 -40.67%
Mar 31, 2013 -56.01%
Dec 31, 2012 256.84%
Sep 30, 2012 -64.26%
Jun 30, 2012 -95.57%
Mar 31, 2012 -97.80%
Dec 31, 2011 -65.99%
Sep 30, 2011 -38.57%
Jun 30, 2011 -18.05%
Mar 31, 2011 1.81%
Dec 31, 2010 -58.13%
Sep 30, 2010 43.94%
Jun 30, 2010 83.01%