Vanda Pharmaceuticals (VNDA) EBITDA Margin (2010 - 2026)
Vanda Pharmaceuticals (VNDA) recorded EBITDA Margin of -121.80% in Q2 2026, down 52.51 percentage points from -69.28% a year earlier and down 29.08 percentage points from the prior quarter.
Powered by 
Analysis
Vanda Pharmaceuticals (VNDA) EBITDA Margin (2010 - 2026) Analysis & Trends
On a TTM basis, Vanda Pharmaceuticals' EBITDA Margin came in at -82.06% as of Jun 30, 2026, down 36.51 percentage points year-over-year; for FY2025, it came in at -66.20%, down 49.85 percentage points from FY2024.
- Annual EBITDA Margin has declined for four straight years, with a five-year change of -78.33 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -16.34% in FY2024 (-10.66 pp), -5.68% in FY2023 (-9.24 pp), 3.56% in FY2022 (-13.20 pp) and 16.76% in FY2021 (+4.63 pp).
- The Q2 2026 figure is the lowest quarterly EBITDA Margin since Q2 2014.
- On a year-over-year basis, EBITDA Margin has declined for 13 consecutive quarters, with an average year-over-year change of -34.44 percentage points over the last eight quarters.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 15.85 percentage points in Q1 2023, against a drop of 63.16 percentage points in Q1 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -92.72% (Q1 2026), -67.01% (Q4 2025) and -51.87% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Vanda Pharmaceuticals | 312.55 Mn | -617.39 Mn | 46.97 Mn | -121.80% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -121.80% |
| Mar 31, 2026 | -92.72% |
| Dec 31, 2025 | -67.01% |
| Sep 30, 2025 | -51.87% |
| Jun 30, 2025 | -69.28% |
| Mar 31, 2025 | -77.93% |
| Dec 31, 2024 | -15.54% |
| Sep 30, 2024 | -18.85% |
| Jun 30, 2024 | -16.11% |
| Mar 31, 2024 | -14.77% |
| Dec 31, 2023 | -13.11% |
| Sep 30, 2023 | -13.90% |
| Jun 30, 2023 | -4.87% |
| Mar 31, 2023 | 4.31% |
| Dec 31, 2022 | 11.31% |
| Sep 30, 2022 | 7.05% |
| Jun 30, 2022 | 6.48% |
| Mar 31, 2022 | -11.54% |
| Dec 31, 2021 | 13.79% |
| Sep 30, 2021 | 16.49% |
API Access
Vanda Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "VNDA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=VNDA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();