Growth Metrics

Vanda Pharmaceuticals (VNDA) EBITDA Margin (2010 - 2026)

Vanda Pharmaceuticals recorded quarterly EBITDA Margin of 96.58% in Q1 2026, down 37.98% quarter-over-quarter from 70.0% in Q4 2025, and down 1506.0% year-over-year from 6.87% in Q1 2025.

Vanda Pharmaceuticals' EBITDA Margin history runs 17 years deep, the most recent figure standing at 96.58% for Q1 2026.

  • In Q1 2026, EBITDA Margin fell 1506.0% year-over-year to 96.58%; the TTM figure through Mar 2026 stood at 73.11% (down 3759.0% YoY), while the FY2025 annual figure was 69.44%, down 4944.0% from the prior year.
  • EBITDA Margin came in at 96.58% for Q1 2026 at Vanda Pharmaceuticals, down from 70.0% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 10.69% in Q4 2022 to a low of 96.58% in Q1 2026.
  • A 5-year average of 28.09% and a median of 18.83% in 2024 frame the typical range for EBITDA Margin.
  • Across the five-year window, EBITDA Margin jumped 1588 bps in 2023 and tumbled 6250 bps in 2025, its largest moves.
  • Vanda Pharmaceuticals' EBITDA Margin stood at 10.69% in 2022, then tumbled by 242 bps to 15.22% in 2023, then retreated by 24 bps to 18.83% in 2024, then sank by 272 bps to 70.0% in 2025, then tumbled by 38 bps to 96.58% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 96.58%, 70.0%, and 55.07% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.24%
10 Vanda Pharmaceuticals 379.35 Mn 177.04 Mn 48.56 Mn -96.58%

Historic Data

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DateValue
Mar 31, 2026 -96.58%
Dec 31, 2025 -70.00%
Sep 30, 2025 -55.07%
Jun 30, 2025 -72.71%
Mar 31, 2025 -81.53%
Dec 31, 2024 -18.83%
Sep 30, 2024 -22.63%
Jun 30, 2024 -19.67%
Mar 31, 2024 -19.02%
Dec 31, 2023 -15.22%
Sep 30, 2023 -14.93%
Jun 30, 2023 -5.74%
Mar 31, 2023 3.67%
Dec 31, 2022 10.69%
Sep 30, 2022 6.44%
Jun 30, 2022 5.86%
Mar 31, 2022 -12.20%
Dec 31, 2021 13.25%
Sep 30, 2021 15.92%
Jun 30, 2021 18.72%
Mar 31, 2021 17.05%
Dec 31, 2020 15.98%
Sep 30, 2020 13.42%
Jun 30, 2020 15.29%
Mar 31, 2020 0.39%
Dec 31, 2019 7.58%
Sep 30, 2019 18.68%
Jun 30, 2019 17.33%
Mar 31, 2019 -3.68%
Dec 31, 2018 17.95%
Sep 30, 2018 13.40%
Jun 30, 2018 9.02%
Mar 31, 2018 6.40%
Dec 31, 2017 -4.17%
Sep 30, 2017 -11.08%
Jun 30, 2017 -4.57%
Mar 31, 2017 -21.13%
Dec 31, 2016 -1.71%
Sep 30, 2016 -1.70%
Jun 30, 2016 -13.29%
Mar 31, 2016 -37.51%
Dec 31, 2015 -46.76%
Sep 30, 2015 -33.66%
Jun 30, 2015 -19.79%
Mar 31, 2015 -46.47%
Dec 31, 2014 453.44%
Sep 30, 2014 -9.80%
Jun 30, 2014 -198.91%
Mar 31, 2014 -290.69%
Dec 31, 2013 -88.71%
Sep 30, 2013 -62.36%
Jun 30, 2013 -41.03%
Mar 31, 2013 -56.58%
Dec 31, 2012 -81.16%
Sep 30, 2012 -65.09%
Jun 30, 2012 -96.50%
Mar 31, 2012 -102.16%
Dec 31, 2011 -70.59%
Sep 30, 2011 -41.32%
Jun 30, 2011 -20.36%
Mar 31, 2011 0.09%
Dec 31, 2010 -16.48%
Sep 30, 2010 10.25%
Jun 30, 2010 75.03%