Upstream Bio (UPB) Times Interest Earned (2023 - 2026)

Upstream Bio's (UPB) quarterly Times Interest Earned came in at -$2.05 in Q1 2026, up 51.26% year-on-year from -$1.36 in Q1 2025, and down 622.29% quarter-over-quarter from -$0.28 in Q4 2025.

Upstream Bio (UPB) Times Interest Earned (2023 - 2026) Analysis & Trends

Upstream Bio's Times Interest Earned history runs 4 years deep, the most recent figure standing at -$2.05 for Q1 2026.

  • On a quarterly basis, Times Interest Earned rose 51.26% year-over-year to -$2.05 in Q1 2026; TTM through Mar 2026 was -$8.1, a 35.08% increase from a year earlier, with the FY2025 full-year figure at -$0.99, up 9.44% from the prior year.
  • Times Interest Earned retreated to -$2.05 in Q1 2026 per UPB's latest filing, from -$0.28 in the prior quarter.
  • Across five years, Times Interest Earned topped out at -$0.28 in Q4 2025 and bottomed at -$4.22 in Q1 2025.
  • The 4-year median for Times Interest Earned is -$0.46 (2024), against an average of -$1.17.
  • Across the five-year window, Times Interest Earned declined 2.3% in 2024 and jumped 51.26% in 2026, its largest moves.
  • Year by year, Times Interest Earned stood at -$0.36 in 2023, then decreased by 2.3% to -$0.37 in 2024, then grew by 22.96% to -$0.28 in 2025, then tumbled by 622.29% to -$2.05 in 2026.
  • Per Business Quant, the three latest UPB Times Interest Earned figures stand at -$2.05 (Q1 2026), -$0.28 (Q4 2025), and -$0.38 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Times Interest Earned (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 658.42
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 7.60
4 NuCana 279.75 Bn 279.75 Bn - -0.22
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 2.71
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 22.72
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -0.38
10 Upstream Bio 347.73 Mn 347.73 Mn -3.94 Mn -2.05

Historic Data

Download Data
DateValue
Mar 31, 2026 -2.05
Dec 31, 2025 -0.28
Sep 30, 2025 -0.38
Jun 30, 2025 -1.12
Mar 31, 2025 -4.22
Dec 31, 2024 -0.37
Sep 30, 2024 -0.54
Dec 31, 2023 -0.36