Upstream Bio (UPB) Interest Expenses (2023 - 2026)
Upstream Bio's (UPB) quarterly Interest Expenses came in at $21.2 million in Q1 2026, up 179.53% year-on-year from $7.6 million in Q1 2025, and down 86.92% quarter-over-quarter from $162.3 million in Q4 2025.
Upstream Bio (UPB) Interest Expenses (2023 - 2026) Analysis & Trends
Upstream Bio's Interest Expenses history runs 4 years deep, the most recent figure standing at $21.2 million for Q1 2026.
- On a quarterly basis, Interest Expenses rose 179.53% year-over-year to $21.2 million in Q1 2026; TTM through Mar 2026 was $21.2 million, a 179.53% increase from a year earlier, with the FY2025 full-year figure at $162.3 million, up 127.71% from the prior year.
- Interest Expenses eased to $21.2 million in Q1 2026 per UPB's latest filing, from $162.3 million in the prior quarter.
- Across five years, Interest Expenses topped out at $162.3 million in Q4 2025 and bottomed at $7.6 million in Q1 2025.
- The 4-year median for Interest Expenses is $39.7 million (2023), against an average of $59.5 million.
- Across the five-year window, Interest Expenses surged 79.53% in 2024 and jumped 183.66% in 2025, its largest moves.
- Year by year, Interest Expenses stood at $39.7 million in 2023, then jumped by 79.53% to $71.3 million in 2024, then soared by 127.71% to $162.3 million in 2025, then sank by 86.92% to $21.2 million in 2026.
- Per Business Quant, the three latest UPB Interest Expenses figures stand at $21.2 million (Q1 2026), $162.3 million (Q4 2025), and $99.5 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Int Expense (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -42,141.15 |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | 100,000.00 |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 32.89 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 420.30 Mn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 28.30 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | 1.17 Bn |
| 10 | Upstream Bio | 343.65 Mn | 343.65 Mn | -3.94 Mn | 21.23 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 21.23 Mn |
| Mar 31, 2026 | 21.23 Mn |
| Dec 31, 2025 | 162.28 Mn |
| Dec 31, 2025 | 162.28 Mn |
| Sep 30, 2025 | 99.54 Mn |
| Sep 30, 2025 | 99.54 Mn |
| Jun 30, 2025 | 39.69 Mn |
| Jun 30, 2025 | 39.69 Mn |
| Mar 31, 2025 | 7.59 Mn |
| Mar 31, 2025 | 7.59 Mn |
| Dec 31, 2024 | 71.27 Mn |
| Dec 31, 2024 | 71.27 Mn |
| Sep 30, 2024 | 35.09 Mn |
| Sep 30, 2024 | 35.09 Mn |
| Dec 31, 2023 | 39.70 Mn |
| Dec 31, 2023 | 39.70 Mn |