Tyra Biosciences (TYRA) Return on Capital Employed [ROCE] (2021 - 2026)
Tyra Biosciences (TYRA) posted Return on Capital Employed [ROCE] of -43.01% for Q2 2026, down 4.84 percentage points from -38.17% a year earlier but up 0.55 percentage points from the prior quarter.
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Analysis
Tyra Biosciences (TYRA) Return on Capital Employed [ROCE] (2021 - 2026) Analysis & Trends
For FY2025, Tyra Biosciences' Return on Capital Employed [ROCE] came in at -43.53%, down 6.34 percentage points from FY2024.
- Annual Return on Capital Employed [ROCE] has declined for four consecutive years, with a four-year change of -26.86 percentage points (FY2021 to FY2025).
- In prior years, Tyra Biosciences' Return on Capital Employed [ROCE] was -37.19% in FY2024 (-2.54 pp), -34.66% in FY2023 (-13.67 pp), -20.99% in FY2022 (-4.32 pp) and -16.67% in FY2021.
- Quarterly Return on Capital Employed [ROCE] has run from a low of -48.43% in Q4 2025 to a high of -8.54% in Q4 2021 over five years.
- On a year-over-year basis, Return on Capital Employed [ROCE] has declined in each of the last six quarters, with an average year-over-year change of -7.23 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Return on Capital Employed [ROCE] in the past five years was Q4 2024, with a gain of 7.73 percentage points; the weakest was Q4 2025, with a drop of 19.28 percentage points.
- According to Business Quant data, Return on Capital Employed [ROCE] for the three prior quarters was -43.56% (Q1 2026), -48.43% (Q4 2025) and -42.59% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 35.41% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 17.52% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 21.60% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 4.65% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 9.91% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 17.37% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -6.15% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 11.32% |
| 10 | Tyra Biosciences | 1.45 Bn | 758.54 Mn | - | -34.70% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -34.70% |
| Jun 30, 2026 | -43.01% |
| Mar 31, 2026 | -43.56% |
| Dec 31, 2025 | -48.43% |
| Sep 30, 2025 | -42.59% |
| Jun 30, 2025 | -38.17% |
| Mar 31, 2025 | -33.52% |
| Dec 31, 2024 | -29.15% |
| Sep 30, 2024 | -26.75% |
| Jun 30, 2024 | -24.59% |
| Mar 31, 2024 | -28.68% |
| Dec 31, 2023 | -36.88% |
| Sep 30, 2023 | -29.62% |
| Jun 30, 2023 | -23.88% |
| Mar 31, 2023 | -22.74% |
| Dec 31, 2022 | -22.20% |
| Sep 30, 2022 | -19.50% |
| Jun 30, 2022 | -16.28% |
| Mar 31, 2022 | -12.39% |
| Dec 31, 2021 | -8.54% |
API Access
Tyra Biosciences Return on Capital Employed [ROCE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=TYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-capital-employed-[roce]", "ticker": "TYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-capital-employed-%5Broce%5D&ticker=TYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();