Taysha Gene Therapies (TSHA) Return on Equity [ROE] (2020 - 2026)
Taysha Gene Therapies (TSHA) recorded Return on Equity [ROE] of -47.48% in Q2 2026, up 9.86 percentage points from -57.34% a year earlier and up 5.75 percentage points from the prior quarter.
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Analysis
Taysha Gene Therapies (TSHA) Return on Equity [ROE] (2020 - 2026) Analysis & Trends
For FY2025, Taysha Gene Therapies reported Return on Equity [ROE] of -63.64%, up 51.91 percentage points from FY2024.
- Annual Return on Equity [ROE] has increased for three straight years, though with a five-year change of -29.38 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -115.55% in FY2024 (+79.12 pp), -194.67% in FY2023 (+150.48 pp), -345.15% in FY2022 (-244.37 pp) and -100.78% in FY2021 (-66.52 pp).
- Quarterly Return on Equity [ROE] has ranged from -2853.50% in Q4 2022 to -40.26% in Q3 2025 over the past five years.
- On a year-over-year basis, Return on Equity [ROE] has increased for five consecutive quarters, with an average year-over-year change of +98.33 percentage points over the last seven quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 2277.22 percentage points in Q4 2023, against a drop of 2705.31 percentage points in Q4 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -53.23% (Q1 2026), -43.50% (Q4 2025) and -40.26% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Taysha Gene Therapies | 1.58 Bn | 1.58 Bn | - | -47.48% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -47.48% |
| Mar 31, 2026 | -53.23% |
| Dec 31, 2025 | -43.50% |
| Sep 30, 2025 | -40.26% |
| Jun 30, 2025 | -57.34% |
| Mar 31, 2025 | -129.67% |
| Dec 31, 2024 | -105.56% |
| Sep 30, 2024 | -82.37% |
| Jun 30, 2024 | -91.20% |
| Mar 31, 2024 | -122.90% |
| Dec 31, 2023 | -576.28% |
| Dec 31, 2022 | -2,853.50% |
| Sep 30, 2022 | -747.00% |
| Jun 30, 2022 | -447.04% |
| Mar 31, 2022 | -264.06% |
| Dec 31, 2021 | -148.19% |
| Sep 30, 2021 | -87.28% |
| Jun 30, 2021 | -52.01% |
| Mar 31, 2021 | -29.32% |
| Dec 31, 2020 | -16.58% |
API Access
Taysha Gene Therapies Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=TSHA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "TSHA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=TSHA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();