Entrada Therapeutics (TRDA) EBITDA Margin (2023 - 2026)

Entrada Therapeutics' quarterly EBITDA Margin came in at 4585.49% in Q1 2026, down 450343.0% year-on-year from N/an in Q1 2025, and down 52.21% quarter-over-quarter from 3012.55% in Q4 2025.

Entrada Therapeutics has reported EBITDA Margin for 4 years, with the latest figure at 4585.49% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin fell 450343.0% year-over-year to 4585.49%; the trailing twelve-month figure through Mar 2026 stood at 2898.38% (down 291316.0% YoY), and the FY2025 full-year result was 562.74%, down 59377.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 4585.49%, down from 3012.55% in the prior quarter.
  • The five-year high for EBITDA Margin was 82.25% in Q3 2023, with the low at 4585.49% in Q1 2026.
  • Average EBITDA Margin over 4 years is 975.79%, with a median of 65.05% recorded in 2024.
  • Year-over-year, EBITDA Margin jumped 20272 bps in 2024 and plunged 450343 bps in 2026.
  • Tracing TRDA's EBITDA Margin over 4 years: stood at 21.16% in 2023, then surged by 101 bps to 0.31% in 2024, then tumbled by 971335 bps to 3012.55% in 2025, then plunged by 52 bps to 4585.49% in 2026.
  • The last three EBITDA Margin figures came in at 4585.49% (Q1 2026), 3012.55% (Q4 2025), and 2720.76% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 Entrada Therapeutics 295.78 Mn 295.78 Mn - -4,585.49%

Historic Data

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DateValue
Mar 31, 2026 -4,585.49%
Dec 31, 2025 -3,012.55%
Sep 30, 2025 -2,720.76%
Jun 30, 2025 -2,212.31%
Mar 31, 2025 -82.06%
Dec 31, 2024 0.31%
Sep 30, 2024 -65.05%
Jun 30, 2024 58.03%
Mar 31, 2024 39.00%
Dec 31, 2023 -21.16%
Sep 30, 2023 82.25%
Jun 30, 2023 -144.69%
Mar 31, 2023 -20.82%