Sutro Biopharma (STRO) Free Cash Flow (2017 - 2025)

Sutro Biopharma recorded quarterly Free Cash Flow of -$26.4 million in Q4 2025, up 31.02% quarter-over-quarter from -$38.2 million in Q3 2025, and up 62.52% year-over-year from -$16.2 million in Q4 2024.

Sutro Biopharma's Free Cash Flow history runs 9 years deep, the most recent figure standing at -$26.4 million for Q4 2025.

  • In Q4 2025, Free Cash Flow rose 62.52% year-over-year to -$26.4 million; the TTM figure through Dec 2025 stood at -$177.2 million (up 7.79% YoY), while the FY2025 annual figure was -$177.2 million, up 7.79% from the prior year.
  • Free Cash Flow came in at -$26.4 million for Q4 2025 at Sutro Biopharma, up from -$38.2 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $67.8 million in Q3 2022 to a low of -$70.4 million in Q4 2024.
  • A 5-year average of -$28.4 million and a median of -$34.3 million in 2021 frame the typical range for Free Cash Flow.
  • Across the five-year window, Free Cash Flow jumped 289.39% in 2022 and sank 545.62% in 2025, its largest moves.
  • Sutro Biopharma's Free Cash Flow stood at -$9.2 million in 2021, then tumbled by 226.79% to -$29.9 million in 2022, then surged by 155.87% to $16.7 million in 2023, then slumped by 520.64% to -$70.4 million in 2024, then jumped by 62.52% to -$26.4 million in 2025.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$26.4 million, -$38.2 million, and -$43.6 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 48.67 Mn
10 Sutro Biopharma 242.87 Mn 242.87 Mn - -26.38 Mn

Historic Data

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DateValue
Dec 31, 2025 -26.38 Mn
Dec 31, 2025 -26.38 Mn
Sep 30, 2025 -38.24 Mn
Sep 30, 2025 -38.24 Mn
Jun 30, 2025 -43.57 Mn
Jun 30, 2025 -43.57 Mn
Mar 31, 2025 -69.06 Mn
Mar 31, 2025 -69.06 Mn
Dec 31, 2024 -70.38 Mn
Dec 31, 2024 -70.38 Mn
Sep 30, 2024 -66.42 Mn
Sep 30, 2024 -66.42 Mn
Jun 30, 2024 9.78 Mn
Jun 30, 2024 9.78 Mn
Mar 31, 2024 -65.19 Mn
Mar 31, 2024 -65.19 Mn
Dec 31, 2023 16.73 Mn
Dec 31, 2023 16.73 Mn
Sep 30, 2023 -36.24 Mn
Sep 30, 2023 -36.24 Mn
Jun 30, 2023 -30.97 Mn
Jun 30, 2023 -30.97 Mn
Mar 31, 2023 -61.36 Mn
Mar 31, 2023 -61.36 Mn
Dec 31, 2022 -29.95 Mn
Dec 31, 2022 -29.95 Mn
Sep 30, 2022 67.83 Mn
Sep 30, 2022 67.83 Mn
Jun 30, 2022 -6.06 Mn
Jun 30, 2022 -6.06 Mn
Mar 31, 2022 -36.14 Mn
Mar 31, 2022 -36.14 Mn
Dec 31, 2021 -9.16 Mn
Dec 31, 2021 -9.16 Mn
Sep 30, 2021 -35.82 Mn
Sep 30, 2021 -35.82 Mn
Jun 30, 2021 -4.26 Mn
Jun 30, 2021 -4.26 Mn
Mar 31, 2021 -32.81 Mn
Mar 31, 2021 -32.81 Mn
Dec 31, 2020 -20.50 Mn
Dec 31, 2020 -20.50 Mn
Sep 30, 2020 -21.91 Mn
Sep 30, 2020 -21.91 Mn
Jun 30, 2020 -13.02 Mn
Jun 30, 2020 -13.02 Mn
Mar 31, 2020 -19.50 Mn
Mar 31, 2020 -19.50 Mn
Dec 31, 2019 -16.63 Mn
Dec 31, 2019 -16.63 Mn
Sep 30, 2019 -15.99 Mn
Sep 30, 2019 -15.99 Mn
Jun 30, 2019 -15.47 Mn
Jun 30, 2019 -15.47 Mn
Mar 31, 2019 -20.42 Mn
Mar 31, 2019 -20.42 Mn
Dec 31, 2018 -5.38 Mn
Dec 31, 2018 -5.38 Mn
Sep 30, 2018 47.21 Mn
Sep 30, 2018 47.21 Mn
Jun 30, 2018 -14.34 Mn
Jun 30, 2018 -14.34 Mn
Mar 31, 2018 -15.02 Mn
Mar 31, 2018 -15.02 Mn
Dec 31, 2017 -7.93 Mn
Dec 31, 2017 -7.93 Mn