Sarepta Therapeutics (SRPT) Net Margin (2010 - 2026)

Sarepta Therapeutics' (SRPT) quarterly Net Margin came in at 45.29% in Q1 2026, up 38093.0% year-on-year from N/an in Q1 2025, and up 170.91% quarter-over-quarter from 63.87% in Q4 2025.

Sarepta Therapeutics (SRPT) Net Margin (2010 - 2026) Analysis & Trends

Sarepta Therapeutics' Net Margin history runs 15 years deep, the most recent figure standing at 45.29% for Q1 2026.

  • On a quarterly basis, Net Margin rose 38093.0% year-over-year to 45.29% in Q1 2026; TTM through Mar 2026 was 2.98%, a 1829.0% increase from a year earlier, with the FY2025 full-year figure at 38.27%, down 5064.0% from the prior year.
  • Net Margin grew to 45.29% in Q1 2026 per SRPT's latest filing, from 63.87% in the prior quarter.
  • Across five years, Net Margin topped out at 45.29% in Q1 2026 and bottomed at 335.64% in Q1 2025.
  • The 5-year median for Net Margin is 9.16% (2023), against an average of 47.39%.
  • Across the five-year window, Net Margin slumped 34448 bps in 2025 and surged 38093 bps in 2026, its largest moves.
  • Year by year, Net Margin stood at 38.02% in 2022, then sank by 89 bps to 4.22% in 2023, then surged by 472 bps to 24.12% in 2024, then plunged by 365 bps to 63.87% in 2025, then jumped by 171 bps to 45.29% in 2026.
  • Per Business Quant, the three latest SRPT Net Margin figures stand at 45.29% (Q1 2026), 63.87% (Q4 2025), and 45.06% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 15.02%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 20.17%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 28.20%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Sarepta Therapeutics 1.66 Bn 1.25 Bn 622.04 Mn 45.29%

Historic Data

Download Data
DateValue
Mar 31, 2026 45.29%
Dec 31, 2025 -63.87%
Sep 30, 2025 -45.06%
Jun 30, 2025 32.23%
Mar 31, 2025 -335.64%
Dec 31, 2024 24.12%
Sep 30, 2024 7.19%
Jun 30, 2024 1.87%
Mar 31, 2024 8.84%
Dec 31, 2023 4.22%
Sep 30, 2023 -13.23%
Jun 30, 2023 -9.16%
Mar 31, 2023 -223.23%
Dec 31, 2022 38.02%
Sep 30, 2022 -111.93%
Jun 30, 2022 -109.58%
Mar 31, 2022 -55.63%
Dec 31, 2021 -68.42%
Sep 30, 2021 -214.02%
Jun 30, 2021 -49.61%