Spruce Biosciences SPRB
NASDAQ SPRB
$50.78 -1.21 (-2.31%)
As of: Aug 21, 2026 · 1:25 PM EDT

Spruce Biosciences (SPRB) Net Income (2019 - 2026)

Spruce Biosciences (SPRB) posted quarterly Net Income of -$21.6 million for Q1 2026, down 52.38% year-over-year from -$45.4 million in Q1 2025, and down 94.51% quarter-over-quarter from -$11.1 million in Q4 2025.

Spruce Biosciences (SPRB) Net Income (2019 - 2026) Analysis & Trends

Spruce Biosciences (SPRB) has reported Net Income for 8 consecutive years, with -$21.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Income fell 52.38% year-over-year to -$21.6 million; the TTM figure through Mar 2026 stood at -$43.0 million (up 22.49% YoY), while the FY2025 annual figure was -$38.6 million, up 27.21% from the prior year.
  • Net Income fell to -$21.6 million in Q1 2026 per SPRB's latest filing, from -$11.1 million in the prior quarter.
  • Across five years, Net Income topped out at -$2.1 million in Q2 2025 and bottomed at -$23.5 million in Q4 2024.
  • Historically, Net Income has averaged -$12.3 million across 5 years, with a median of -$12.2 million in 2022.
  • Annual changes were most pronounced in 2024 — Net Income slumped 108.37% — and 2025, when it surged 77.49%.
  • Spruce Biosciences' Net Income stood at -$10.1 million in 2022, then fell by 11.57% to -$11.3 million in 2023, then plunged by 108.37% to -$23.5 million in 2024, then jumped by 52.62% to -$11.1 million in 2025, then slumped by 94.51% to -$21.6 million in 2026.
  • Business Quant data shows SPRB's Net Income at -$21.6 million in Q1 2026, -$11.1 million in Q4 2025, and -$8.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Vertex Pharmaceuticals 139.24 Bn 131.39 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 86.01 Bn 78.02 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 65.61 Bn 60.42 Bn 1.37 Bn 482.00 Mn
4 Moderna 56.92 Bn 51.78 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 42.17 Bn 37.07 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.27 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 27.77 Bn 9.38 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.52 Bn 26.36 Bn 358.27 Mn -13.27 Mn
9 Royalty Pharma 27.36 Bn 26.52 Bn - 81.49 Mn
10 Spruce Biosciences 123.45 Mn 123.45 Mn - -16.84 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -25.26 Mn
Mar 31, 2026 -21.64 Mn
Dec 31, 2025 -11.12 Mn
Sep 30, 2025 -8.21 Mn
Jun 30, 2025 -2.07 Mn
Mar 31, 2025 -14.20 Mn
Dec 31, 2024 -23.48 Mn
Sep 30, 2024 -8.67 Mn
Jun 30, 2024 -9.18 Mn
Mar 31, 2024 -11.63 Mn
Dec 31, 2023 -11.27 Mn
Sep 30, 2023 -13.73 Mn
Jun 30, 2023 -13.97 Mn
Mar 31, 2023 -13.05 Mn
Dec 31, 2022 -10.10 Mn
Sep 30, 2022 -12.17 Mn
Jun 30, 2022 -12.44 Mn
Mar 31, 2022 -12.19 Mn
Dec 31, 2021 -9.62 Mn
Sep 30, 2021 -18.50 Mn