Growth Metrics

SOPHiA GENETICS (SOPH) Gross Margin (2020 - 2025)

SOPHiA GENETICS's Gross Margin history spans 6 years, with the latest figure at 67.68% for Q4 2025.

  • On a quarterly basis, Gross Margin fell 56.0% to 67.68% in Q4 2025 year-over-year; TTM through Dec 2025 was 67.4%, a 2.0% decrease, with the full-year FY2025 number at 67.4%, down 2.0% from a year prior.
  • Gross Margin hit 67.68% in Q4 2025 for SOPHiA GENETICS, up from 66.32% in the prior quarter.
  • Over the last five years, Gross Margin for SOPH hit a ceiling of 71.96% in Q4 2022 and a floor of 61.21% in Q2 2021.
  • Historically, Gross Margin has averaged 66.36% across 5 years, with a median of 66.85% in 2023.
  • The widest YoY moves for Gross Margin: up 6317bps in 2021, down -583bps in 2021.
  • Tracing SOPH's Gross Margin over 5 years: stood at 62.45% in 2021, then grew by 15bps to 71.96% in 2022, then decreased by -3bps to 69.79% in 2023, then dropped by -2bps to 68.25% in 2024, then dropped by -1bps to 67.68% in 2025.
  • Business Quant data shows Gross Margin for SOPH at 67.68% in Q4 2025, 66.32% in Q3 2025, and 66.97% in Q2 2025.