SOPHiA GENETICS (SOPH) Gross Margin (2020 - 2026)
SOPHiA GENETICS (SOPH) recorded Gross Margin of 64.61% in the quarter ended Jun 30, 2026, down 2.35 percentage points from 66.97% a year earlier and down 3.39 percentage points from the prior quarter.
SOPHiA GENETICS (SOPH) Gross Margin (2020 - 2026) Analysis & Trends
On a TTM basis, SOPHiA GENETICS's Gross Margin came in at 66.63% as of Jun 30, 2026, down 1.15 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at 67.40%, down 0.02 percentage points from the prior year.
- Annual Gross Margin has a five-year change of +5.10 percentage points (years ended Dec 2020 to Dec 2025).
- Across earlier years, Gross Margin came in at 67.42% in the year ended Dec 31, 2024 (-1.39 pp), 68.80% in the year ended Dec 31, 2023 (+3.09 pp), 65.71% in the year ended Dec 31, 2022 (+3.36 pp) and 62.35% in the year ended Dec 31, 2021 (+0.06 pp).
- The figure for the quarter ended Jun 30, 2026 is the lowest quarterly Gross Margin since the quarter ended Sep 30, 2022.
- On a year-over-year basis, Gross Margin has declined for five consecutive quarters, with an average year-over-year change of -0.80 percentage points over the last eight quarters.
- Peak year-over-year performance for Gross Margin in the last five years was a gain of 9.51 percentage points in the quarter ended Dec 31, 2022, against a drop of 3.47 percentage points in the quarter ended Mar 31, 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at 68.01% (quarter ended Mar 31, 2026), 67.68% (quarter ended Dec 31, 2025) and 66.32% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Bryn | 945.00 Bn | 945.00 Bn | - | - |
| 2 | Veeva Systems | 45.35 Bn | 17.59 Bn | 695.95 Mn | 75.00% |
| 3 | Samsara | 22.20 Bn | 18.97 Bn | 392.58 Mn | 77.21% |
| 4 | Toast | 17.53 Bn | 10.20 Bn | 516.00 Mn | 27.04% |
| 5 | Ptc | 15.47 Bn | 14.28 Bn | 490.47 Mn | 81.74% |
| 6 | Trimble | 13.41 Bn | 12.48 Bn | 674.90 Mn | 69.43% |
| 7 | Duolingo | 12.56 Bn | 7.73 Bn | 216.74 Mn | 72.62% |
| 8 | Manhattan Associates | 11.77 Bn | 10.77 Bn | 168.33 Mn | 56.53% |
| 9 | Costar | 10.95 Bn | 4.91 Bn | 728.00 Mn | 78.70% |
| 10 | SOPHiA GENETICS | 581.45 Mn | 256.49 Mn | 15.06 Mn | 64.61% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 64.61% |
| Mar 31, 2026 | 68.01% |
| Dec 31, 2025 | 67.68% |
| Sep 30, 2025 | 66.32% |
| Jun 30, 2025 | 66.97% |
| Mar 31, 2025 | 68.67% |
| Dec 31, 2024 | 68.25% |
| Sep 30, 2024 | 67.20% |
| Jun 30, 2024 | 68.17% |
| Mar 31, 2024 | 65.94% |
| Dec 31, 2023 | 69.79% |
| Sep 30, 2023 | 69.15% |
| Jun 30, 2023 | 66.74% |
| Mar 31, 2023 | 69.41% |
| Dec 31, 2022 | 71.96% |
| Sep 30, 2022 | 62.61% |
| Jun 30, 2022 | 65.31% |
| Mar 31, 2022 | 63.60% |
| Dec 31, 2021 | 62.45% |
| Sep 30, 2021 | 63.17% |
SOPHiA GENETICS Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "SOPH", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=SOPH&period=max&api_key=YOUR_API_KEY");
const data = await res.json();