Senti Biosciences Holdings (SNTI) Return on Equity [ROE] (2022 - 2026)
Senti Biosciences Holdings (SNTI) posted Return on Equity [ROE] of -6112.52% for Q2 2026, down 5912.01 percentage points from -200.51% a year earlier.
Powered by 
Analysis
Senti Biosciences Holdings (SNTI) Return on Equity [ROE] (2022 - 2026) Analysis & Trends
For FY2025, Senti Biosciences Holdings' Return on Equity [ROE] came in at -440.35%, down 326.29 percentage points from FY2024.
- Annual Return on Equity [ROE] shows a three-year change of +296.20 percentage points (FY2022 to FY2025).
- In prior years, Senti Biosciences Holdings' Return on Equity [ROE] was -114.06% in FY2024 (-40.87 pp), -73.19% in FY2023 (+663.37 pp) and -736.56% in FY2022.
- The Q2 2026 figure stands as the lowest quarterly Return on Equity [ROE] in data going back to Q2 2022.
- On a year-over-year basis, Return on Equity [ROE] increased in three of the last seven quarters, with an average year-over-year change of -978.39 percentage points.
- The strongest year-over-year quarter for Return on Equity [ROE] in the past five years was Q2 2023, with a gain of 236.80 percentage points; the weakest was Q2 2026, with a drop of 5912.01 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Senti Biosciences Holdings | 4.36 Mn | -39.74 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | -1,264.34% |
| Dec 31, 2025 | -896.25% |
| Sep 30, 2025 | -290.37% |
| Jun 30, 2025 | -186.59% |
| Mar 31, 2025 | -172.55% |
| Dec 31, 2024 | -253.54% |
| Sep 30, 2024 | -235.76% |
| Jun 30, 2024 | -113.63% |
| Mar 31, 2024 | -104.79% |
| Dec 31, 2023 | -94.84% |
| Sep 30, 2023 | -78.24% |
| Jun 30, 2023 | -68.91% |
| Mar 31, 2023 | -54.36% |
| Dec 31, 2022 | -43.50% |
| Sep 30, 2022 | -34.56% |
| Jun 30, 2022 | -281.40% |
API Access
Senti Biosciences Holdings Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SNTI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SNTI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SNTI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();