Senti Biosciences (SNTI) Profit After Tax (2021 - 2025)

Senti Biosciences' quarterly Profit After Tax came in at -$14.4 million in Q4 2025, down 2227.26% year-on-year from $678291.0 in Q4 2024, and up 20.4% quarter-over-quarter from -$18.1 million in Q3 2025.

Senti Biosciences has reported Profit After Tax for 5 years, with the latest figure at -$14.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Profit After Tax fell 2227.26% year-over-year to -$14.4 million; the trailing twelve-month figure through Dec 2025 stood at -$61.4 million (down 16.29% YoY), and the FY2025 full-year result was -$61.4 million, down 16.29% from the prior year.
  • Profit After Tax for Q4 2025 stood at -$14.4 million, up from -$18.1 million in the prior quarter.
  • The five-year high for Profit After Tax was -$1178.0 in Q1 2021, with the low at -$83.4 million in Q4 2023.
  • Average Profit After Tax over 5 years is -$18.8 million, with a median of -$14.3 million recorded in 2025.
  • Year-over-year, Profit After Tax tumbled 1002276.91% in 2022 and surged 99.26% in 2024.
  • Tracing SNTI's Profit After Tax over 5 years: stood at -$3.9 million in 2021, then tumbled by 1409.17% to -$58.2 million in 2022, then plunged by 43.28% to -$83.4 million in 2023, then surged by 99.26% to -$620000.0 in 2024, then slumped by 2227.26% to -$14.4 million in 2025.
  • The last three Profit After Tax figures came in at -$14.4 million (Q4 2025), -$18.1 million (Q3 2025), and -$14.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.63 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 205.99 Mn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -14.43 Mn
Sep 30, 2025 -18.13 Mn
Jun 30, 2025 -14.73 Mn
Mar 31, 2025 -14.11 Mn
Dec 31, 2024 -620,000.00
Sep 30, 2024 -28.87 Mn
Jun 30, 2024 -11.20 Mn
Mar 31, 2024 -12.11 Mn
Dec 31, 2023 -83.41 Mn
Sep 30, 2023 -14.92 Mn
Jun 30, 2023 -18.70 Mn
Mar 31, 2023 -18.72 Mn
Dec 31, 2022 -58.21 Mn
Sep 30, 2022 -16.64 Mn
Jun 30, 2022 -11.55 Mn
Mar 31, 2022 -11.81 Mn
Dec 31, 2021 -3.86 Mn
Sep 30, 2021 -11.41 Mn
Jun 30, 2021 -12.01 Mn
Mar 31, 2021 -1,178.00