Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.39 -0.05 (-10.87%)
At close: Aug 21, 2026 · 4:00 PM EDT

Senti Biosciences Holdings (SNTI) Profit After Tax (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly Profit After Tax of -$14.5 million for Q4 2025, down 2233.39% year-over-year from $678123.5 in Q4 2024, and up 20.19% quarter-over-quarter from -$18.1 million in Q3 2025.

Senti Biosciences Holdings (SNTI) Profit After Tax (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Profit After Tax history runs 5 years deep, the most recent figure standing at -$14.5 million for Q4 2025.

  • In Q4 2025, Profit After Tax fell 2233.39% year-over-year to -$14.5 million; the TTM figure through Dec 2025 stood at -$61.4 million (down 16.36% YoY), while the FY2025 annual figure was -$61.4 million, down 16.36% from the prior year.
  • Profit After Tax for Q4 2025 stood at -$14.5 million, up from -$18.1 million in the prior quarter.
  • The five-year high for Profit After Tax was -$620000.0 in Q4 2024, with the low at -$71.1 million in Q4 2023.
  • The 5-year median for Profit After Tax is -$14.6 million (2025), against an average of -$18.8 million.
  • The sharpest annual moves came in 2024 and 2025: Profit After Tax soared 99.13% in 2024, then sank 2233.39% in 2025.
  • Senti Biosciences Holdings' Profit After Tax stood at -$3.9 million in 2021, then slumped by 1187.63% to -$49.7 million in 2022, then plunged by 43.07% to -$71.1 million in 2023, then jumped by 99.13% to -$620000.0 in 2024, then tumbled by 2233.39% to -$14.5 million in 2025.
  • Business Quant data shows SNTI's Profit After Tax at -$14.5 million in Q4 2025, -$18.1 million in Q3 2025, and -$14.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -16.62 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 81.49 Mn
10 Senti Biosciences Holdings 12.06 Mn 12.06 Mn - -12.75 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -14.47 Mn
Sep 30, 2025 -18.13 Mn
Jun 30, 2025 -14.73 Mn
Mar 31, 2025 -14.11 Mn
Dec 31, 2024 -620,000.00
Sep 30, 2024 -28.87 Mn
Jun 30, 2024 -11.20 Mn
Mar 31, 2024 -12.11 Mn
Dec 31, 2023 -71.06 Mn
Sep 30, 2023 -14.92 Mn
Jun 30, 2023 -18.70 Mn
Mar 31, 2023 -18.72 Mn
Dec 31, 2022 -49.67 Mn
Sep 30, 2022 -16.64 Mn
Jun 30, 2022 -11.55 Mn
Mar 31, 2022 -11.81 Mn
Dec 31, 2021 -3.86 Mn
Sep 30, 2021 -11.41 Mn
Jun 30, 2021 -12.01 Mn
Mar 31, 2021 -21.00 Mn