Senti Biosciences Holdings (SNTI) Profit After Tax (2021 - 2025)

Senti Biosciences Holdings (SNTI) recorded quarterly Profit After Tax of -$14.4 million in Q4 2025, up 20.4% quarter-over-quarter from -$18.1 million in Q3 2025, and down 2227.26% on a YoY basis from $678291.0 in Q4 2024.

Senti Biosciences Holdings (SNTI) Profit After Tax (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Profit After Tax history runs 5 years deep, the most recent figure standing at -$14.4 million for Q4 2025.

  • In Q4 2025, Profit After Tax fell 2227.26% year-over-year to -$14.4 million; the TTM figure through Dec 2025 stood at -$61.4 million (down 16.29% YoY), while the FY2025 annual figure was -$61.4 million, down 16.29% from the prior year.
  • Profit After Tax was -$14.4 million for Q4 2025 at Senti Biosciences Holdings, up from -$18.1 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$1178.0 in Q1 2021 to a low of -$83.4 million in Q4 2023.
  • Historically, Profit After Tax has averaged -$18.8 million across 5 years, with a median of -$14.3 million in 2025.
  • The sharpest annual moves came in 2022 and 2024: Profit After Tax tumbled 1002276.91% in 2022, then soared 99.26% in 2024.
  • A 5-year view of Profit After Tax shows it stood at -$3.9 million in 2021, then plunged by 1409.17% to -$58.2 million in 2022, then sank by 43.28% to -$83.4 million in 2023, then jumped by 99.26% to -$620000.0 in 2024, then tumbled by 2227.26% to -$14.4 million in 2025.
  • The last three Profit After Tax figures came in at -$14.4 million (Q4 2025), -$18.1 million (Q3 2025), and -$14.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 30.90 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.46 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.63 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -753,254.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.03 Bn
9 Abivax 90.15 Bn 90.15 Bn - -56.74 Mn
10 Senti Biosciences Holdings 21.76 Mn 21.76 Mn - -14.43 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -14.43 Mn
Sep 30, 2025 -18.13 Mn
Jun 30, 2025 -14.73 Mn
Mar 31, 2025 -14.11 Mn
Dec 31, 2024 -620,000.00
Sep 30, 2024 -28.87 Mn
Jun 30, 2024 -11.20 Mn
Mar 31, 2024 -12.11 Mn
Dec 31, 2023 -83.41 Mn
Sep 30, 2023 -14.92 Mn
Jun 30, 2023 -18.70 Mn
Mar 31, 2023 -18.72 Mn
Dec 31, 2022 -58.21 Mn
Sep 30, 2022 -16.64 Mn
Jun 30, 2022 -11.55 Mn
Mar 31, 2022 -11.81 Mn
Dec 31, 2021 -3.86 Mn
Sep 30, 2021 -11.41 Mn
Jun 30, 2021 -12.01 Mn
Mar 31, 2021 -1,178.00