Senti Biosciences (SNTI) Free Cash Flow (2021 - 2025)

Senti Biosciences' quarterly Free Cash Flow came in at -$6.9 million in Q4 2025, up 49.13% year-on-year from -$4.6 million in Q4 2024, and up 27.22% quarter-over-quarter from -$9.4 million in Q3 2025.

Senti Biosciences has reported Free Cash Flow for 5 years, with the latest figure at -$6.9 million in Q4 2025.

  • For the quarter ending Q4 2025, Free Cash Flow rose 49.13% year-over-year to -$6.9 million; the trailing twelve-month figure through Dec 2025 stood at -$43.6 million (down 5.35% YoY), and the FY2025 full-year result was -$43.6 million, down 5.35% from the prior year.
  • Free Cash Flow for Q4 2025 stood at -$6.9 million, up from -$9.4 million in the prior quarter.
  • The five-year high for Free Cash Flow was -$934675.0 in Q2 2021, with the low at -$33.6 million in Q3 2022.
  • Average Free Cash Flow over 5 years is -$11.6 million, with a median of -$9.4 million recorded in 2025.
  • Year-over-year, Free Cash Flow slumped 1862.94% in 2022 and surged 84.51% in 2023.
  • Tracing SNTI's Free Cash Flow over 5 years: stood at -$4.5 million in 2021, then sank by 290.69% to -$17.5 million in 2022, then soared by 59.81% to -$7.0 million in 2023, then slumped by 91.73% to -$13.5 million in 2024, then surged by 49.13% to -$6.9 million in 2025.
  • The last three Free Cash Flow figures came in at -$6.9 million (Q4 2025), -$9.4 million (Q3 2025), and -$13.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 48.67 Mn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -6.88 Mn
Dec 31, 2025 -6.88 Mn
Sep 30, 2025 -9.45 Mn
Sep 30, 2025 -9.45 Mn
Jun 30, 2025 -13.10 Mn
Jun 30, 2025 -13.10 Mn
Mar 31, 2025 -14.22 Mn
Mar 31, 2025 -14.22 Mn
Dec 31, 2024 -13.52 Mn
Dec 31, 2024 -13.52 Mn
Sep 30, 2024 -7.87 Mn
Sep 30, 2024 -7.87 Mn
Jun 30, 2024 -8.36 Mn
Jun 30, 2024 -8.36 Mn
Mar 31, 2024 -11.68 Mn
Mar 31, 2024 -11.68 Mn
Dec 31, 2023 -7.05 Mn
Dec 31, 2023 -7.05 Mn
Sep 30, 2023 -5.21 Mn
Sep 30, 2023 -5.21 Mn
Jun 30, 2023 -19.09 Mn
Jun 30, 2023 -19.09 Mn
Mar 31, 2023 -21.06 Mn
Mar 31, 2023 -21.06 Mn
Dec 31, 2022 -17.54 Mn
Dec 31, 2022 -17.54 Mn
Sep 30, 2022 -33.61 Mn
Sep 30, 2022 -33.61 Mn
Jun 30, 2022 -7.69 Mn
Jun 30, 2022 -7.69 Mn
Mar 31, 2022 -17.44 Mn
Mar 31, 2022 -17.44 Mn
Dec 31, 2021 -4.49 Mn
Dec 31, 2021 -4.49 Mn
Sep 30, 2021 -1.71 Mn
Sep 30, 2021 -1.71 Mn
Jun 30, 2021 -934,675.00
Jun 30, 2021 -934,675.00