Senti Biosciences (SNTI) Enterprise Value (2021 - 2025)

Senti Biosciences' quarterly Enterprise Value came in at -$16.4 million in Q4 2025, up 65.99% year-on-year from -$9.9 million in Q4 2024, and down 34.12% quarter-over-quarter from -$12.2 million in Q3 2025.

Senti Biosciences has reported Enterprise Value for 5 years, with the latest figure at -$16.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Enterprise Value rose 65.99% year-over-year to -$16.4 million; the trailing twelve-month figure through Dec 2025 stood at -$16.4 million (up 65.99% YoY), and the FY2025 full-year result was -$16.4 million, up 65.99% from the prior year.
  • Enterprise Value for Q4 2025 stood at -$16.4 million, down from -$12.2 million in the prior quarter.
  • The five-year high for Enterprise Value was -$10.5 million in Q3 2024, with the low at -$139.8 million in Q2 2022.
  • Average Enterprise Value over 5 years is -$52.5 million, with a median of -$39.4 million recorded in 2023.
  • Year-over-year, Enterprise Value slumped 99.54% in 2023 and jumped 73.42% in 2024.
  • Tracing SNTI's Enterprise Value over 5 years: stood at -$56.0 million in 2021, then tumbled by 75.9% to -$98.6 million in 2022, then soared by 63.58% to -$35.9 million in 2023, then slumped by 34.48% to -$48.3 million in 2024, then surged by 65.99% to -$16.4 million in 2025.
  • The last three Enterprise Value figures came in at -$16.4 million (Q4 2025), -$12.2 million (Q3 2025), and -$21.6 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 Senti Biosciences Holdings 22.25 Mn 22.25 Mn - -

Historic Data

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DateValue
Dec 31, 2025 -16.42 Mn
Sep 30, 2025 -12.24 Mn
Jun 30, 2025 -21.60 Mn
Mar 31, 2025 -33.80 Mn
Dec 31, 2024 -48.28 Mn
Sep 30, 2024 -10.48 Mn
Jun 30, 2024 -15.90 Mn
Mar 31, 2024 -23.70 Mn
Dec 31, 2023 -35.90 Mn
Sep 30, 2023 -39.43 Mn
Jun 30, 2023 -59.64 Mn
Mar 31, 2023 -76.11 Mn
Dec 31, 2022 -98.56 Mn
Sep 30, 2022 -114.94 Mn
Jun 30, 2022 -139.80 Mn
Mar 31, 2022 -38.14 Mn
Dec 31, 2021 -56.03 Mn
Sep 30, 2021 -73.69 Mn
Jun 30, 2021 -82.94 Mn