Senti Biosciences Holdings SNTI
NASDAQ SNTI
$0.39 -0.05 (-10.87%)
At close: Aug 21, 2026 · 4:00 PM EDT

Senti Biosciences Holdings (SNTI) Change in Cash (2021 - 2025)

Senti Biosciences Holdings (SNTI) posted quarterly Change in Cash of $4.2 million for Q4 2025, down 88.97% year-over-year from $37.8 million in Q4 2024, and up 144.68% quarter-over-quarter from -$9.3 million in Q3 2025.

Senti Biosciences Holdings (SNTI) Change in Cash (2021 - 2025) Analysis & Trends

Senti Biosciences Holdings' Change in Cash history runs 5 years deep, the most recent figure standing at $4.2 million for Q4 2025.

  • In Q4 2025, Change in Cash fell 88.97% year-over-year to $4.2 million; the TTM figure through Dec 2025 stood at -$31.9 million (down 357.68% YoY), while the FY2025 annual figure was -$31.9 million, down 357.68% from the prior year.
  • Change in Cash for Q4 2025 stood at $4.2 million, up from -$9.3 million in the prior quarter.
  • The five-year high for Change in Cash was $101.7 million in Q2 2022, with the low at -$57.2 million in Q4 2022.
  • The 5-year median for Change in Cash is -$6.4 million (2023), against an average of -$1.9 million.
  • Peak annual rise in Change in Cash reached 9167.98% in 2022, while the deepest fall reached 6537.26% in 2022.
  • Senti Biosciences Holdings' Change in Cash stood at $889323.0 in 2021, then plunged by 6537.26% to -$57.2 million in 2022, then surged by 88.86% to -$6.4 million in 2023, then jumped by 692.08% to $37.8 million in 2024, then slumped by 88.97% to $4.2 million in 2025.
  • Business Quant data shows SNTI's Change in Cash at $4.2 million in Q4 2025, -$9.3 million in Q3 2025, and -$12.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -185.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 427.25 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -2.94 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -2.83 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -37.42 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 225.59 Mn
10 Senti Biosciences Holdings 12.06 Mn 12.06 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 4.17 Mn
Sep 30, 2025 -9.32 Mn
Jun 30, 2025 -12.25 Mn
Mar 31, 2025 -14.46 Mn
Dec 31, 2024 37.78 Mn
Sep 30, 2024 -5.37 Mn
Jun 30, 2024 -8.35 Mn
Mar 31, 2024 -11.70 Mn
Dec 31, 2023 -6.38 Mn
Sep 30, 2023 5.74 Mn
Jun 30, 2023 4.94 Mn
Mar 31, 2023 -25.84 Mn
Dec 31, 2022 -57.25 Mn
Sep 30, 2022 -24.82 Mn
Jun 30, 2022 101.66 Mn
Mar 31, 2022 -17.89 Mn
Dec 31, 2021 889,323.00
Sep 30, 2021 984,544.00
Jun 30, 2021 1.10 Mn