Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026)
Syndax Pharmaceuticals (SNDX) recorded quarterly Return on Capital Employed of 53.86% in Q1 2026, up 17.04% quarter-over-quarter from 64.92% in Q4 2025, and up 461.0% on a YoY basis from 9.6% in Q1 2025.
Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026) Analysis & Trends
Syndax Pharmaceuticals' Return on Capital Employed history runs 11 years deep, the most recent figure standing at 53.86% for Q1 2026.
- In Q1 2026, Return on Capital Employed rose 461.0% year-over-year to 53.86%; the TTM figure through Mar 2026 stood at 53.86% (up 461.0% YoY), while the FY2025 annual figure was 53.85%, up 624.0% from the prior year.
- Return on Capital Employed was 53.86% for Q1 2026 at Syndax Pharmaceuticals, up from 64.92% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 4.08% in Q1 2022 to a low of 81.94% in Q3 2024.
- Historically, Return on Capital Employed has averaged 46.71% across 5 years, with a median of 51.6% in 2023.
- The sharpest annual moves came in 2022 and 2023: Return on Capital Employed surged 3640 bps in 2022, then tumbled 4775 bps in 2023.
- A 5-year view of Return on Capital Employed shows it stood at 38.0% in 2022, then slumped by 35 bps to 51.33% in 2023, then slumped by 40 bps to 72.0% in 2024, then increased by 10 bps to 64.92% in 2025, then gained by 17 bps to 53.86% in 2026.
- The last three Return on Capital Employed figures came in at 53.86% (Q1 2026), 64.92% (Q4 2025), and 66.75% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Syndax Pharmaceuticals | 1.69 Bn | 1.34 Bn | 53.02 Mn | -53.86% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -53.86% |
| Dec 31, 2025 | -64.92% |
| Sep 30, 2025 | -66.75% |
| Jun 30, 2025 | -67.08% |
| Mar 31, 2025 | -58.47% |
| Dec 31, 2024 | -72.00% |
| Sep 30, 2024 | -81.94% |
| Jun 30, 2024 | -61.60% |
| Mar 31, 2024 | -49.98% |
| Dec 31, 2023 | -51.33% |
| Sep 30, 2023 | -51.60% |
| Jun 30, 2023 | -41.61% |
| Mar 31, 2023 | -35.38% |
| Dec 31, 2022 | -38.00% |
| Sep 30, 2022 | -3.86% |
| Jun 30, 2022 | 0.30% |
| Mar 31, 2022 | 4.08% |
| Dec 31, 2021 | 8.10% |
| Sep 30, 2021 | -40.16% |
| Jun 30, 2021 | -36.11% |