Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026)

Syndax Pharmaceuticals (SNDX) recorded quarterly Return on Capital Employed of 53.86% in Q1 2026, up 17.04% quarter-over-quarter from 64.92% in Q4 2025, and up 461.0% on a YoY basis from 9.6% in Q1 2025.

Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026) Analysis & Trends

Syndax Pharmaceuticals' Return on Capital Employed history runs 11 years deep, the most recent figure standing at 53.86% for Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 461.0% year-over-year to 53.86%; the TTM figure through Mar 2026 stood at 53.86% (up 461.0% YoY), while the FY2025 annual figure was 53.85%, up 624.0% from the prior year.
  • Return on Capital Employed was 53.86% for Q1 2026 at Syndax Pharmaceuticals, up from 64.92% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 4.08% in Q1 2022 to a low of 81.94% in Q3 2024.
  • Historically, Return on Capital Employed has averaged 46.71% across 5 years, with a median of 51.6% in 2023.
  • The sharpest annual moves came in 2022 and 2023: Return on Capital Employed surged 3640 bps in 2022, then tumbled 4775 bps in 2023.
  • A 5-year view of Return on Capital Employed shows it stood at 38.0% in 2022, then slumped by 35 bps to 51.33% in 2023, then slumped by 40 bps to 72.0% in 2024, then increased by 10 bps to 64.92% in 2025, then gained by 17 bps to 53.86% in 2026.
  • The last three Return on Capital Employed figures came in at 53.86% (Q1 2026), 64.92% (Q4 2025), and 66.75% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Syndax Pharmaceuticals 1.69 Bn 1.34 Bn 53.02 Mn -53.86%

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.86%
Dec 31, 2025 -64.92%
Sep 30, 2025 -66.75%
Jun 30, 2025 -67.08%
Mar 31, 2025 -58.47%
Dec 31, 2024 -72.00%
Sep 30, 2024 -81.94%
Jun 30, 2024 -61.60%
Mar 31, 2024 -49.98%
Dec 31, 2023 -51.33%
Sep 30, 2023 -51.60%
Jun 30, 2023 -41.61%
Mar 31, 2023 -35.38%
Dec 31, 2022 -38.00%
Sep 30, 2022 -3.86%
Jun 30, 2022 0.30%
Mar 31, 2022 4.08%
Dec 31, 2021 8.10%
Sep 30, 2021 -40.16%
Jun 30, 2021 -36.11%