Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026)

Syndax Pharmaceuticals' (SNDX) quarterly Return on Capital Employed came in at 53.86% in Q1 2026, up 461.0% year-on-year from 9.6% in Q1 2025, and up 17.04% quarter-over-quarter from 64.92% in Q4 2025.

Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026) Analysis & Trends

Syndax Pharmaceuticals' Return on Capital Employed history runs 11 years deep, the most recent figure standing at 53.86% for Q1 2026.

  • On a quarterly basis, Return on Capital Employed rose 461.0% year-over-year to 53.86% in Q1 2026; TTM through Mar 2026 was 53.86%, a 461.0% increase from a year earlier, with the FY2025 full-year figure at 53.85%, up 624.0% from the prior year.
  • Return on Capital Employed improved to 53.86% in Q1 2026 per SNDX's latest filing, from 64.92% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 4.08% in Q1 2022 and bottomed at 81.94% in Q3 2024.
  • The 5-year median for Return on Capital Employed is 51.6% (2023), against an average of 46.71%.
  • Across the five-year window, Return on Capital Employed jumped 3640 bps in 2022 and tumbled 4775 bps in 2023, its largest moves.
  • Year by year, Return on Capital Employed stood at 38.0% in 2022, then plunged by 35 bps to 51.33% in 2023, then plunged by 40 bps to 72.0% in 2024, then increased by 10 bps to 64.92% in 2025, then gained by 17 bps to 53.86% in 2026.
  • Per Business Quant, the three latest SNDX Return on Capital Employed figures stand at 53.86% (Q1 2026), 64.92% (Q4 2025), and 66.75% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Syndax Pharmaceuticals 1.87 Bn 1.52 Bn 53.02 Mn -53.86%

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.86%
Dec 31, 2025 -64.92%
Sep 30, 2025 -66.75%
Jun 30, 2025 -67.08%
Mar 31, 2025 -58.47%
Dec 31, 2024 -72.00%
Sep 30, 2024 -81.94%
Jun 30, 2024 -61.60%
Mar 31, 2024 -49.98%
Dec 31, 2023 -51.33%
Sep 30, 2023 -51.60%
Jun 30, 2023 -41.61%
Mar 31, 2023 -35.38%
Dec 31, 2022 -38.00%
Sep 30, 2022 -3.86%
Jun 30, 2022 0.30%
Mar 31, 2022 4.08%
Dec 31, 2021 8.10%
Sep 30, 2021 -40.16%
Jun 30, 2021 -36.11%