Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026)
Syndax Pharmaceuticals' (SNDX) quarterly Return on Capital Employed came in at 53.86% in Q1 2026, up 461.0% year-on-year from 9.6% in Q1 2025, and up 17.04% quarter-over-quarter from 64.92% in Q4 2025.
Syndax Pharmaceuticals (SNDX) Return on Capital Employed (2016 - 2026) Analysis & Trends
Syndax Pharmaceuticals' Return on Capital Employed history runs 11 years deep, the most recent figure standing at 53.86% for Q1 2026.
- On a quarterly basis, Return on Capital Employed rose 461.0% year-over-year to 53.86% in Q1 2026; TTM through Mar 2026 was 53.86%, a 461.0% increase from a year earlier, with the FY2025 full-year figure at 53.85%, up 624.0% from the prior year.
- Return on Capital Employed improved to 53.86% in Q1 2026 per SNDX's latest filing, from 64.92% in the prior quarter.
- Across five years, Return on Capital Employed topped out at 4.08% in Q1 2022 and bottomed at 81.94% in Q3 2024.
- The 5-year median for Return on Capital Employed is 51.6% (2023), against an average of 46.71%.
- Across the five-year window, Return on Capital Employed jumped 3640 bps in 2022 and tumbled 4775 bps in 2023, its largest moves.
- Year by year, Return on Capital Employed stood at 38.0% in 2022, then plunged by 35 bps to 51.33% in 2023, then plunged by 40 bps to 72.0% in 2024, then increased by 10 bps to 64.92% in 2025, then gained by 17 bps to 53.86% in 2026.
- Per Business Quant, the three latest SNDX Return on Capital Employed figures stand at 53.86% (Q1 2026), 64.92% (Q4 2025), and 66.75% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -31.80% |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 10.46% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -68.47% |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 21.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 10.19% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -68.84% |
| 10 | Syndax Pharmaceuticals | 1.87 Bn | 1.52 Bn | 53.02 Mn | -53.86% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -53.86% |
| Dec 31, 2025 | -64.92% |
| Sep 30, 2025 | -66.75% |
| Jun 30, 2025 | -67.08% |
| Mar 31, 2025 | -58.47% |
| Dec 31, 2024 | -72.00% |
| Sep 30, 2024 | -81.94% |
| Jun 30, 2024 | -61.60% |
| Mar 31, 2024 | -49.98% |
| Dec 31, 2023 | -51.33% |
| Sep 30, 2023 | -51.60% |
| Jun 30, 2023 | -41.61% |
| Mar 31, 2023 | -35.38% |
| Dec 31, 2022 | -38.00% |
| Sep 30, 2022 | -3.86% |
| Jun 30, 2022 | 0.30% |
| Mar 31, 2022 | 4.08% |
| Dec 31, 2021 | 8.10% |
| Sep 30, 2021 | -40.16% |
| Jun 30, 2021 | -36.11% |