Syndax Pharmaceuticals SNDX
NASDAQ SNDX
$20.58 -0.10 (-0.51%)
As of: Sep 4, 2026 · 2:27 PM EDT

Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026)

Syndax Pharmaceuticals (SNDX) posted quarterly Operating Income of -$34.2 million for Q1 2026, up 59.17% year-over-year from -$21.5 million in Q1 2025, and up 45.32% quarter-over-quarter from -$62.5 million in Q4 2025.

Analysis

Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026) Analysis & Trends

Syndax Pharmaceuticals' Operating Income history runs 12 years deep, the most recent figure standing at -$34.2 million for Q1 2026.

  • In Q1 2026, Operating Income rose 59.17% year-over-year to -$34.2 million; the TTM figure through Mar 2026 stood at -$223.5 million (up 35.0% YoY), while the FY2025 annual figure was -$273.1 million, up 19.6% from the prior year.
  • Operating Income for Q1 2026 stood at -$34.2 million, up from -$62.5 million in the prior quarter.
  • The five-year high for Operating Income was -$34.2 million in Q1 2026, with the low at -$96.4 million in Q4 2024.
  • The 5-year median for Operating Income is -$57.4 million (2025), against an average of -$60.5 million.
  • The sharpest annual moves came in 2022 and 2026: Operating Income sank 143.9% in 2022, then jumped 59.17% in 2026.
  • Syndax Pharmaceuticals' Operating Income stood at -$42.0 million in 2022, then tumbled by 85.34% to -$77.9 million in 2023, then slipped by 23.7% to -$96.4 million in 2024, then soared by 35.09% to -$62.5 million in 2025, then surged by 45.32% to -$34.2 million in 2026.
  • Business Quant data shows SNDX's Operating Income at -$34.2 million in Q1 2026, -$62.5 million in Q4 2025, and -$57.4 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 138.78 Bn 130.92 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.50 Bn 77.51 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.51 Bn 58.32 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.06 Bn 52.92 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.04 Bn 44.04 Bn - -505.13 Mn
6 BeOne Medicines 40.04 Bn 34.94 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.45 Bn 32.14 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.41 Bn 27.57 Bn - 133.12 Mn
9 Insmed 27.42 Bn 26.26 Bn 358.27 Mn -1.55 Mn
10 Syndax Pharmaceuticals 1.83 Bn 1.28 Bn 60.67 Mn -40.00 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -40.00 Mn
Mar 31, 2026 -34.20 Mn
Dec 31, 2025 -62.55 Mn
Sep 30, 2025 -57.43 Mn
Jun 30, 2025 -69.35 Mn
Mar 31, 2025 -83.76 Mn
Dec 31, 2024 -96.37 Mn
Sep 30, 2024 -89.58 Mn
Jun 30, 2024 -74.22 Mn
Mar 31, 2024 -79.51 Mn
Dec 31, 2023 -77.91 Mn
Sep 30, 2023 -56.36 Mn
Jun 30, 2023 -49.68 Mn
Mar 31, 2023 -46.02 Mn
Dec 31, 2022 -42.03 Mn
Sep 30, 2022 -35.14 Mn
Jun 30, 2022 -37.72 Mn
Mar 31, 2022 -36.86 Mn
Dec 31, 2021 95.75 Mn
Sep 30, 2021 -20.03 Mn