Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026)

Syndax Pharmaceuticals' (SNDX) quarterly Operating Income came in at -$34.2 million in Q1 2026, up 59.17% year-on-year from -$21.5 million in Q1 2025, and up 45.32% quarter-over-quarter from -$62.5 million in Q4 2025.

Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026) Analysis & Trends

Syndax Pharmaceuticals' Operating Income history runs 12 years deep, the most recent figure standing at -$34.2 million for Q1 2026.

  • On a quarterly basis, Operating Income rose 59.17% year-over-year to -$34.2 million in Q1 2026; TTM through Mar 2026 was -$223.5 million, a 35.0% increase from a year earlier, with the FY2025 full-year figure at -$273.1 million, up 19.6% from the prior year.
  • Operating Income rose to -$34.2 million in Q1 2026 per SNDX's latest filing, from -$62.5 million in the prior quarter.
  • Across five years, Operating Income topped out at -$34.2 million in Q1 2026 and bottomed at -$96.4 million in Q4 2024.
  • The 5-year median for Operating Income is -$57.4 million (2025), against an average of -$60.5 million.
  • Across the five-year window, Operating Income slumped 143.9% in 2022 and jumped 59.17% in 2026, its largest moves.
  • Year by year, Operating Income stood at -$42.0 million in 2022, then slumped by 85.34% to -$77.9 million in 2023, then dropped by 23.7% to -$96.4 million in 2024, then jumped by 35.09% to -$62.5 million in 2025, then soared by 45.32% to -$34.2 million in 2026.
  • Per Business Quant, the three latest SNDX Operating Income figures stand at -$34.2 million (Q1 2026), -$62.5 million (Q4 2025), and -$57.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Syndax Pharmaceuticals 1.87 Bn 1.52 Bn 53.02 Mn -34.20 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -34.20 Mn
Dec 31, 2025 -62.55 Mn
Sep 30, 2025 -57.43 Mn
Jun 30, 2025 -69.35 Mn
Mar 31, 2025 -83.76 Mn
Dec 31, 2024 -96.37 Mn
Sep 30, 2024 -89.58 Mn
Jun 30, 2024 -74.22 Mn
Mar 31, 2024 -79.51 Mn
Dec 31, 2023 -77.91 Mn
Sep 30, 2023 -56.36 Mn
Jun 30, 2023 -49.68 Mn
Mar 31, 2023 -46.02 Mn
Dec 31, 2022 -42.03 Mn
Sep 30, 2022 -35.14 Mn
Jun 30, 2022 -37.72 Mn
Mar 31, 2022 -36.86 Mn
Dec 31, 2021 95.75 Mn
Sep 30, 2021 -20.03 Mn
Jun 30, 2021 -22.33 Mn