Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026)
Syndax Pharmaceuticals' (SNDX) quarterly Operating Income came in at -$34.2 million in Q1 2026, up 59.17% year-on-year from -$21.5 million in Q1 2025, and up 45.32% quarter-over-quarter from -$62.5 million in Q4 2025.
Syndax Pharmaceuticals (SNDX) Operating Income (2015 - 2026) Analysis & Trends
Syndax Pharmaceuticals' Operating Income history runs 12 years deep, the most recent figure standing at -$34.2 million for Q1 2026.
- On a quarterly basis, Operating Income rose 59.17% year-over-year to -$34.2 million in Q1 2026; TTM through Mar 2026 was -$223.5 million, a 35.0% increase from a year earlier, with the FY2025 full-year figure at -$273.1 million, up 19.6% from the prior year.
- Operating Income rose to -$34.2 million in Q1 2026 per SNDX's latest filing, from -$62.5 million in the prior quarter.
- Across five years, Operating Income topped out at -$34.2 million in Q1 2026 and bottomed at -$96.4 million in Q4 2024.
- The 5-year median for Operating Income is -$57.4 million (2025), against an average of -$60.5 million.
- Across the five-year window, Operating Income slumped 143.9% in 2022 and jumped 59.17% in 2026, its largest moves.
- Year by year, Operating Income stood at -$42.0 million in 2022, then slumped by 85.34% to -$77.9 million in 2023, then dropped by 23.7% to -$96.4 million in 2024, then jumped by 35.09% to -$62.5 million in 2025, then soared by 45.32% to -$34.2 million in 2026.
- Per Business Quant, the three latest SNDX Operating Income figures stand at -$34.2 million (Q1 2026), -$62.5 million (Q4 2025), and -$57.4 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Syndax Pharmaceuticals | 1.87 Bn | 1.52 Bn | 53.02 Mn | -34.20 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -34.20 Mn |
| Dec 31, 2025 | -62.55 Mn |
| Sep 30, 2025 | -57.43 Mn |
| Jun 30, 2025 | -69.35 Mn |
| Mar 31, 2025 | -83.76 Mn |
| Dec 31, 2024 | -96.37 Mn |
| Sep 30, 2024 | -89.58 Mn |
| Jun 30, 2024 | -74.22 Mn |
| Mar 31, 2024 | -79.51 Mn |
| Dec 31, 2023 | -77.91 Mn |
| Sep 30, 2023 | -56.36 Mn |
| Jun 30, 2023 | -49.68 Mn |
| Mar 31, 2023 | -46.02 Mn |
| Dec 31, 2022 | -42.03 Mn |
| Sep 30, 2022 | -35.14 Mn |
| Jun 30, 2022 | -37.72 Mn |
| Mar 31, 2022 | -36.86 Mn |
| Dec 31, 2021 | 95.75 Mn |
| Sep 30, 2021 | -20.03 Mn |
| Jun 30, 2021 | -22.33 Mn |