Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026)
Syndax Pharmaceuticals (SNDX) recorded EBITDA Margin of -42.88% in Q3 2026, up 75.64 percentage points from -118.51% a year earlier and up 4.78 percentage points from the prior quarter.
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Analysis
Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026) Analysis & Trends
On a TTM basis, Syndax Pharmaceuticals' EBITDA Margin came in at -55.27% as of Sep 30, 2026, up 209.77 percentage points year-over-year; for FY2025, it came in at -154.83%, up 1245.68 percentage points from FY2024.
- Annual EBITDA Margin has a five-year change of +4547.48 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -1400.52% in FY2024 and 18.80% in FY2021 (+4721.11 pp).
- The Q3 2026 figure is the highest quarterly EBITDA Margin since Q4 2021.
- On a year-over-year basis, EBITDA Margin has increased for six consecutive quarters, with an average year-over-year change of +696.83 percentage points over the last six quarters.
- Per Business Quant, the preceding three quarters came in at -47.66% (Q2 2026), -46.48% (Q1 2026) and -86.64% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 36.69% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 40.60% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 39.77% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 46.62% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 42.49% |
| 10 | Syndax Pharmaceuticals | 854.00 Mn | -867.10 Mn | 69.30 Mn | -42.88% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -42.88% |
| Jun 30, 2026 | -47.66% |
| Mar 31, 2026 | -46.48% |
| Dec 31, 2025 | -86.64% |
| Sep 30, 2025 | -118.51% |
| Jun 30, 2025 | -182.56% |
| Mar 31, 2025 | -417.35% |
| Dec 31, 2024 | -1,150.30% |
| Sep 30, 2024 | -716.60% |
| Jun 30, 2024 | -2,120.37% |
| Dec 31, 2021 | 75.65% |
| Sep 30, 2021 | -161.81% |
| Jun 30, 2021 | -5,890.50% |
| Mar 31, 2021 | -7,162.80% |
| Dec 31, 2020 | -5,220.79% |
| Sep 30, 2020 | -5,232.19% |
| Jun 30, 2020 | -4,376.78% |
| Mar 31, 2020 | -3,978.10% |
| Dec 31, 2019 | -3,561.32% |
| Sep 30, 2019 | -3,515.83% |
API Access
Syndax Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=SNDX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "SNDX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=SNDX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();