Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026)

Syndax Pharmaceuticals' (SNDX) quarterly EBITDA Margin came in at 52.73% in Q1 2026, up 36518.0% year-on-year from N/an in Q1 2025, and up 42.06% quarter-over-quarter from 91.01% in Q4 2025.

Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026) Analysis & Trends

Syndax Pharmaceuticals' EBITDA Margin history runs 10 years deep, the most recent figure standing at 52.73% for Q1 2026.

  • On a quarterly basis, EBITDA Margin rose 36518.0% year-over-year to 52.73% in Q1 2026; TTM through Mar 2026 was 102.81%, a 68379.0% increase from a year earlier, with the FY2025 full-year figure at 158.45%, up 127598.0% from the prior year.
  • EBITDA Margin improved to 52.73% in Q1 2026 per SNDX's latest filing, from 91.01% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 52.73% in Q1 2026 and bottomed at 2120.46% in Q2 2024.
  • The 3-year median for EBITDA Margin is 300.31% (2025), against an average of 620.17%.
  • Across the five-year window, EBITDA Margin surged 193775 bps in 2025 and soared 36518 bps in 2026, its largest moves.
  • Year by year, EBITDA Margin stood at 1254.75% in 2024, then jumped by 93 bps to 91.01% in 2025, then soared by 42 bps to 52.73% in 2026.
  • Per Business Quant, the three latest SNDX EBITDA Margin figures stand at 52.73% (Q1 2026), 91.01% (Q4 2025), and 125.19% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Syndax Pharmaceuticals 1.87 Bn 1.52 Bn 53.02 Mn -52.73%

Historic Data

Download Data
DateValue
Mar 31, 2026 -52.73%
Dec 31, 2025 -91.01%
Sep 30, 2025 -125.19%
Jun 30, 2025 -182.71%
Mar 31, 2025 -417.91%
Dec 31, 2024 -1,254.75%
Sep 30, 2024 -716.62%
Jun 30, 2024 -2,120.46%
Dec 31, 2021 75.65%
Sep 30, 2021 -161.87%
Jun 30, 2021 -5,892.88%
Mar 31, 2021 -7,167.02%
Dec 31, 2020 -5,226.32%
Sep 30, 2020 -5,238.26%
Jun 30, 2020 -4,382.59%
Mar 31, 2020 -3,984.17%
Dec 31, 2019 -3,738.16%
Sep 30, 2019 -3,469.39%
Jun 30, 2019 -4,056.46%
Mar 31, 2019 -3,907.92%