Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026)

Syndax Pharmaceuticals (SNDX) recorded quarterly EBITDA Margin of 52.73% in Q1 2026, up 42.06% quarter-over-quarter from 91.01% in Q4 2025, and up 36518.0% on a YoY basis from N/an in Q1 2025.

Syndax Pharmaceuticals (SNDX) EBITDA Margin (2015 - 2026) Analysis & Trends

Syndax Pharmaceuticals' EBITDA Margin history runs 10 years deep, the most recent figure standing at 52.73% for Q1 2026.

  • In Q1 2026, EBITDA Margin rose 36518.0% year-over-year to 52.73%; the TTM figure through Mar 2026 stood at 102.81% (up 65467.0% YoY), while the FY2025 annual figure was 158.45%, up 127598.0% from the prior year.
  • EBITDA Margin was 52.73% for Q1 2026 at Syndax Pharmaceuticals, up from 91.01% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 52.73% in Q1 2026 to a low of 1946.4% in Q2 2024.
  • Historically, EBITDA Margin has averaged 591.78% across 3 years, with a median of 300.31% in 2025.
  • The sharpest annual moves came in 2025 and 2026: EBITDA Margin surged 176369 bps in 2025, then jumped 36518 bps in 2026.
  • A 3-year view of EBITDA Margin shows it stood at 1254.75% in 2024, then jumped by 93 bps to 91.01% in 2025, then soared by 42 bps to 52.73% in 2026.
  • The last three EBITDA Margin figures came in at 52.73% (Q1 2026), 91.01% (Q4 2025), and 125.19% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Syndax Pharmaceuticals 1.69 Bn 1.34 Bn 53.02 Mn -52.73%

Historic Data

Download Data
DateValue
Mar 31, 2026 -52.73%
Dec 31, 2025 -91.01%
Sep 30, 2025 -125.19%
Jun 30, 2025 -182.71%
Mar 31, 2025 -417.91%
Dec 31, 2024 -1,254.75%
Sep 30, 2024 -663.50%
Jun 30, 2024 -1,946.40%
Dec 31, 2021 75.65%
Sep 30, 2021 -166.83%
Jun 30, 2021 -6,042.74%
Mar 31, 2021 -7,311.35%
Dec 31, 2020 -5,226.32%
Sep 30, 2020 -5,409.23%
Jun 30, 2020 -4,483.64%
Mar 31, 2020 -4,007.39%
Dec 31, 2019 -3,738.16%
Sep 30, 2019 -3,393.67%
Jun 30, 2019 -3,922.43%
Mar 31, 2019 -3,764.91%