Syndax Pharmaceuticals (SNDX) EBITDA (2015 - 2026)
Syndax Pharmaceuticals (SNDX) recorded quarterly EBITDA of -$34.2 million in Q1 2026, up 45.32% quarter-over-quarter from -$62.5 million in Q4 2025, and up 59.17% on a YoY basis from -$21.5 million in Q1 2025.
Syndax Pharmaceuticals (SNDX) EBITDA (2015 - 2026) Analysis & Trends
Syndax Pharmaceuticals' EBITDA history runs 12 years deep, the most recent figure standing at -$34.2 million for Q1 2026.
- In Q1 2026, EBITDA rose 59.17% year-over-year to -$34.2 million; the TTM figure through Mar 2026 stood at -$223.5 million (up 32.51% YoY), while the FY2025 annual figure was -$273.1 million, up 19.6% from the prior year.
- EBITDA was -$34.2 million for Q1 2026 at Syndax Pharmaceuticals, up from -$62.5 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$34.2 million in Q1 2026 to a low of -$96.4 million in Q4 2024.
- Historically, EBITDA has averaged -$58.6 million across 5 years, with a median of -$57.4 million in 2025.
- The sharpest annual moves came in 2022 and 2026: EBITDA slumped 143.9% in 2022, then surged 59.17% in 2026.
- A 5-year view of EBITDA shows it stood at -$42.0 million in 2022, then plunged by 85.34% to -$77.9 million in 2023, then dropped by 23.7% to -$96.4 million in 2024, then jumped by 35.09% to -$62.5 million in 2025, then soared by 45.32% to -$34.2 million in 2026.
- The last three EBITDA figures came in at -$34.2 million (Q1 2026), -$62.5 million (Q4 2025), and -$57.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Syndax Pharmaceuticals | 1.69 Bn | 1.34 Bn | 53.02 Mn | -34.20 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -34.20 Mn |
| Dec 31, 2025 | -62.55 Mn |
| Sep 30, 2025 | -57.43 Mn |
| Jun 30, 2025 | -69.35 Mn |
| Mar 31, 2025 | -83.76 Mn |
| Dec 31, 2024 | -96.37 Mn |
| Sep 30, 2024 | -82.94 Mn |
| Jun 30, 2024 | -68.12 Mn |
| Mar 31, 2024 | -73.37 Mn |
| Dec 31, 2023 | -77.91 Mn |
| Sep 30, 2023 | -51.03 Mn |
| Jun 30, 2023 | -44.85 Mn |
| Mar 31, 2023 | -40.66 Mn |
| Dec 31, 2022 | -42.03 Mn |
| Sep 30, 2022 | -35.67 Mn |
| Jun 30, 2022 | -38.27 Mn |
| Mar 31, 2022 | -37.85 Mn |
| Dec 31, 2021 | 95.75 Mn |
| Sep 30, 2021 | -20.65 Mn |
| Jun 30, 2021 | -22.90 Mn |