Syndax Pharmaceuticals (SNDX) EBITDA (2015 - 2026)

Syndax Pharmaceuticals (SNDX) recorded quarterly EBITDA of -$34.2 million in Q1 2026, up 45.32% quarter-over-quarter from -$62.5 million in Q4 2025, and up 59.17% on a YoY basis from -$21.5 million in Q1 2025.

Syndax Pharmaceuticals (SNDX) EBITDA (2015 - 2026) Analysis & Trends

Syndax Pharmaceuticals' EBITDA history runs 12 years deep, the most recent figure standing at -$34.2 million for Q1 2026.

  • In Q1 2026, EBITDA rose 59.17% year-over-year to -$34.2 million; the TTM figure through Mar 2026 stood at -$223.5 million (up 32.51% YoY), while the FY2025 annual figure was -$273.1 million, up 19.6% from the prior year.
  • EBITDA was -$34.2 million for Q1 2026 at Syndax Pharmaceuticals, up from -$62.5 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$34.2 million in Q1 2026 to a low of -$96.4 million in Q4 2024.
  • Historically, EBITDA has averaged -$58.6 million across 5 years, with a median of -$57.4 million in 2025.
  • The sharpest annual moves came in 2022 and 2026: EBITDA slumped 143.9% in 2022, then surged 59.17% in 2026.
  • A 5-year view of EBITDA shows it stood at -$42.0 million in 2022, then plunged by 85.34% to -$77.9 million in 2023, then dropped by 23.7% to -$96.4 million in 2024, then jumped by 35.09% to -$62.5 million in 2025, then soared by 45.32% to -$34.2 million in 2026.
  • The last three EBITDA figures came in at -$34.2 million (Q1 2026), -$62.5 million (Q4 2025), and -$57.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Syndax Pharmaceuticals 1.69 Bn 1.34 Bn 53.02 Mn -34.20 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -34.20 Mn
Dec 31, 2025 -62.55 Mn
Sep 30, 2025 -57.43 Mn
Jun 30, 2025 -69.35 Mn
Mar 31, 2025 -83.76 Mn
Dec 31, 2024 -96.37 Mn
Sep 30, 2024 -82.94 Mn
Jun 30, 2024 -68.12 Mn
Mar 31, 2024 -73.37 Mn
Dec 31, 2023 -77.91 Mn
Sep 30, 2023 -51.03 Mn
Jun 30, 2023 -44.85 Mn
Mar 31, 2023 -40.66 Mn
Dec 31, 2022 -42.03 Mn
Sep 30, 2022 -35.67 Mn
Jun 30, 2022 -38.27 Mn
Mar 31, 2022 -37.85 Mn
Dec 31, 2021 95.75 Mn
Sep 30, 2021 -20.65 Mn
Jun 30, 2021 -22.90 Mn