Silence Therapeutics (SLN) Return on Sales (2024 - 2026)

Silence Therapeutics' (SLN) quarterly Return on Sales came in at 0.35% in Q1 2026, up 165.0% year-on-year from 0.13% in Q1 2025, and up 90.62% quarter-over-quarter from 3.78% in Q4 2025.

Silence Therapeutics (SLN) Return on Sales (2024 - 2026) Analysis & Trends

Silence Therapeutics has disclosed Return on Sales across 3 years of filings, most recently posting 0.35% for Q1 2026.

  • Return on Sales for Q1 2026 came in at 0.35%, up 165.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 0.93% (down 91.0% YoY), and the FY2025 annual result was 1.6%, down 159.0% from the prior year.
  • Return on Sales came in at 0.35% for Q1 2026 at Silence Therapeutics, up from 3.78% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.0% in Q4 2024 to a low of 3.78% in Q4 2025.
  • The 3-year median for Return on Sales is 0.35% (2026), against an average of 1.04%.
  • Across the five-year window, Return on Sales slumped 378 bps in 2025 and surged 165 bps in 2026, its largest moves.
  • Silence Therapeutics' Return on Sales stood at 0.0% in 2024, then sank by 77830 bps to 3.78% in 2025, then soared by 91 bps to 0.35% in 2026.
  • The last three Return on Sales figures came in at 0.35% (Q1 2026), 3.78% (Q4 2025), and 1.32% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00%
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 0.00%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Silence Therapeutics 966.41 Mn 896.33 Mn 411,000.00 -0.35%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.35%
Dec 31, 2025 -3.78%
Sep 30, 2025 -1.32%
Jun 30, 2025 -1.37%
Mar 31, 2025 -2.01%
Dec 31, 2024 0.00%
Sep 30, 2024 -0.24%
Jun 30, 2024 -0.26%
Mar 31, 2024 0.00%