Silence Therapeutics (SLN) Return on Equity [ROE] (2021 - 2026)
Silence Therapeutics' Return on Equity [ROE] came in at -136.45% for the quarter ended Jun 30, 2026, down 59.97 percentage points from -76.49% a year earlier and down 2.10 percentage points from the prior quarter.
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Analysis
Silence Therapeutics (SLN) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Silence Therapeutics' Return on Equity [ROE] was -90.27%, down 32.19 percentage points from the prior year.
- Return on Equity [ROE] carries a five-year change of +127.81 percentage points (years ended Dec 2020 to Dec 2025).
- Going back by year, Return on Equity [ROE] was -58.08% in the year ended Dec 31, 2024 (+160.32 pp), -218.40% in the year ended Dec 31, 2023 (+38.89 pp), -257.29% in the year ended Dec 31, 2022 (+206.87 pp) and -464.17% in the year ended Dec 31, 2021 (-246.09 pp).
- Year-over-year, Return on Equity [ROE] has declined for three consecutive quarters.
- Business Quant data shows SLN's Return on Equity [ROE] at -134.35% (quarter ended Mar 31, 2026), -129.96% (quarter ended Dec 31, 2025) and -76.73% (quarter ended Sep 30, 2025) in the three quarters before the quarter ended Jun 30, 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 74.39% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 19.33% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | - |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 5.63% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 21.60% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 72.13% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -31.17% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 4.66% |
| 10 | Silence Therapeutics | 935.01 Mn | 862.91 Mn | - | -136.45% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -136.45% |
| Mar 31, 2026 | -134.35% |
| Dec 31, 2025 | -129.96% |
| Sep 30, 2025 | -76.73% |
| Jun 30, 2025 | -76.06% |
| Mar 31, 2025 | -57.52% |
| Dec 31, 2024 | -34.38% |
| Sep 30, 2024 | -55.75% |
| Jun 30, 2024 | -33.68% |
| Mar 31, 2024 | -49.05% |
| Dec 31, 2023 | -233.30% |
| Sep 30, 2023 | -260.92% |
| Jun 30, 2023 | -277.32% |
| Mar 31, 2023 | -220.32% |
| Dec 31, 2022 | -154.05% |
| Sep 30, 2022 | -286.88% |
| Mar 31, 2022 | -632.42% |
| Dec 31, 2021 | -324.24% |
| Sep 30, 2021 | -211.88% |
API Access
Silence Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SLN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SLN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SLN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();