Silence Therapeutics (SLN) Return on Equity [ROE] (2024 - 2026)
Silence Therapeutics' Return on Equity [ROE] came in at -136.45% for the quarter ended Jun 30, 2026, down 59.97 percentage points from -76.49% a year earlier and down 2.10 percentage points from the prior quarter.
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Analysis
Silence Therapeutics (SLN) Return on Equity [ROE] (2024 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, Silence Therapeutics' Return on Equity [ROE] was -90.27%, down 32.19 percentage points from the prior year.
- Return on Equity [ROE] carries a five-year change of +127.81 percentage points (years ended Dec 2020 to Dec 2025).
- Going back by year, Return on Equity [ROE] was -58.08% in the year ended Dec 31, 2024 (+160.32 pp), -218.40% in the year ended Dec 31, 2023 (+38.89 pp), -257.29% in the year ended Dec 31, 2022 (+206.87 pp) and -464.17% in the year ended Dec 31, 2021 (-246.09 pp).
- Year-over-year, Return on Equity [ROE] has declined for three consecutive quarters.
- Business Quant data shows SLN's Return on Equity [ROE] at -134.35% (quarter ended Mar 31, 2026), -129.96% (quarter ended Dec 31, 2025) and -76.73% (quarter ended Sep 30, 2025) in the three quarters before the quarter ended Jun 30, 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Silence Therapeutics | 516.41 Mn | 444.31 Mn | - | -136.45% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -136.45% |
| Mar 31, 2026 | -134.35% |
| Dec 31, 2025 | -129.96% |
| Sep 30, 2025 | -76.73% |
| Jun 30, 2025 | -76.49% |
| Mar 31, 2025 | -57.97% |
| Dec 31, 2024 | -34.76% |
API Access
Silence Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SLN&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SLN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SLN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();