Silence Therapeutics (SLN) Operating Income (2024 - 2026)

Silence Therapeutics' (SLN) quarterly Operating Income came in at -$15.7 million in Q1 2026, up 44.61% year-on-year from -$10.9 million in Q1 2025, and down 127.87% quarter-over-quarter from $56.5 million in Q4 2025.

Silence Therapeutics (SLN) Operating Income (2024 - 2026) Analysis & Trends

Silence Therapeutics has disclosed Operating Income across 3 years of filings, most recently posting -$15.7 million for Q1 2026.

  • Operating Income for Q1 2026 came in at -$15.7 million, up 44.61% year-over-year; the trailing twelve-month figure through Mar 2026 was -$9.5 million (up 89.0% YoY), and the FY2025 annual result was -$22.2 million, up 65.02% from the prior year.
  • Operating Income came in at -$15.7 million for Q1 2026 at Silence Therapeutics, down from $56.5 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $56.5 million in Q4 2025 to a low of -$30.0 million in Q3 2024.
  • The 3-year median for Operating Income is -$23.4 million (2024), against an average of -$11.2 million.
  • Peak annual rise in Operating Income reached 1397.47% in 2025, while the deepest fall reached 409.03% in 2025.
  • Silence Therapeutics' Operating Income stood at -$4.4 million in 2024, then soared by 1397.47% to $56.5 million in 2025, then sank by 127.87% to -$15.7 million in 2026.
  • The last three Operating Income figures came in at -$15.7 million (Q1 2026), $56.5 million (Q4 2025), and -$26.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Silence Therapeutics 966.41 Mn 896.33 Mn 411,000.00 -15.74 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -15.74 Mn
Dec 31, 2025 56.47 Mn
Sep 30, 2025 -26.24 Mn
Jun 30, 2025 -23.96 Mn
Mar 31, 2025 -28.41 Mn
Dec 31, 2024 -4.35 Mn
Sep 30, 2024 -30.00 Mn
Jun 30, 2024 -23.39 Mn
Mar 31, 2024 -5.58 Mn