Growth Metrics

Silence Therapeutics (SLN) Operating Expenses (2020 - 2026)

Silence Therapeutics recorded quarterly Operating Expenses of $16.1 million in Q1 2026, down 48.59% quarter-over-quarter from $31.4 million in Q4 2025, and up 13245.45% year-over-year from N/an in Q1 2025.

Silence Therapeutics' Operating Expenses history runs 7 years deep, the most recent figure standing at $16.1 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 13245.45% year-over-year to $16.1 million; the TTM figure through Mar 2026 stood at $77.3 million (up 373.42% YoY), while the FY2025 annual figure was $91.4 million, up 584.74% from the prior year.
  • Operating Expenses came in at $16.1 million for Q1 2026 at Silence Therapeutics, down from $31.4 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $143.1 million in Q4 2023 to a low of -$27.2 million in Q3 2024.
  • A 5-year average of $11.0 million and a median of -$3.5 million in 2024 frame the typical range for Operating Expenses.
  • Across the five-year window, Operating Expenses tumbled 98.16% in 2024 and jumped 13245.45% in 2026, its largest moves.
  • Silence Therapeutics' Operating Expenses stood at $115.6 million in 2022, then gained by 23.76% to $143.1 million in 2023, then sank by 98.16% to $2.6 million in 2024, then surged by 1090.71% to $31.4 million in 2025, then plunged by 48.59% to $16.1 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $16.1 million, $31.4 million, and $26.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Silence Therapeutics 924.61 Mn 854.53 Mn 411,000.00 16.15 Mn

Historic Data

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DateValue
Mar 31, 2026 16.15 Mn
Dec 31, 2025 31.41 Mn
Sep 30, 2025 26.34 Mn
Jun 30, 2025 3.38 Mn
Mar 31, 2025 121,000.00
Dec 31, 2024 2.64 Mn
Sep 30, 2024 -27.16 Mn
Jun 30, 2024 -3.86 Mn
Mar 31, 2024 -3.51 Mn
Dec 31, 2023 143.07 Mn
Sep 30, 2023 -17.59 Mn
Jun 30, 2023 -22.19 Mn
Mar 31, 2023 -23.08 Mn
Dec 31, 2022 115.60 Mn
Sep 30, 2022 -17.20 Mn
Jun 30, 2022 -19.37 Mn
Mar 31, 2022 -17.94 Mn
Dec 31, 2021 119.85 Mn
Sep 30, 2021 -18.46 Mn
Jun 30, 2021 -18.93 Mn
Mar 31, 2021 -15.45 Bn
Dec 31, 2020 28.40 Bn
Sep 30, 2020 -7.92 Bn